BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 29316330)

  • 1. RNA-Seq Highlights High Clonal Variation in Monoclonal Antibody Producing CHO Cells.
    Orellana CA; Marcellin E; Palfreyman RW; Munro TP; Gray PP; Nielsen LK
    Biotechnol J; 2018 Mar; 13(3):e1700231. PubMed ID: 29316330
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutation Detection in an Antibody-Producing Chinese Hamster Ovary Cell Line by Targeted RNA Sequencing.
    Zhang S; Hughes JD; Murgolo N; Levitan D; Chen J; Liu Z; Shi S
    Biomed Res Int; 2016; 2016():8356435. PubMed ID: 27088091
    [TBL] [Abstract][Full Text] [Related]  

  • 3. High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis.
    Orellana CA; Marcellin E; Schulz BL; Nouwens AS; Gray PP; Nielsen LK
    J Proteome Res; 2015 Feb; 14(2):609-18. PubMed ID: 25495469
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetic analysis of the clonal stability of Chinese hamster ovary cells for recombinant protein production.
    Li H; Chen K; Wang Z; Li D; Lin J; Yu C; Yu F; Wang X; Huang L; Jiang C; Gu H; Fang J
    Mol Biosyst; 2016 Jan; 12(1):102-9. PubMed ID: 26563441
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hyperosmotic stimulus study discloses benefits in ATP supply and reveals miRNA/mRNA targets to improve recombinant protein production of CHO cells.
    Pfizenmaier J; Junghans L; Teleki A; Takors R
    Biotechnol J; 2016 Aug; 11(8):1037-47. PubMed ID: 27214792
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Growth Rate Changes in CHO Host Cells Are Associated with Karyotypic Heterogeneity.
    Baik JY; Lee KH
    Biotechnol J; 2018 Mar; 13(3):e1700230. PubMed ID: 28865132
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Optimization of cell line development in the GS-CHO expression system using a high-throughput, single cell-based clone selection system.
    Nakamura T; Omasa T
    J Biosci Bioeng; 2015 Sep; 120(3):323-9. PubMed ID: 25792187
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?
    Chusainow J; Yang YS; Yeo JH; Toh PC; Asvadi P; Wong NS; Yap MG
    Biotechnol Bioeng; 2009 Mar; 102(4):1182-96. PubMed ID: 18979540
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells.
    Fan L; Kadura I; Krebs LE; Hatfield CC; Shaw MM; Frye CC
    Biotechnol Bioeng; 2012 Apr; 109(4):1007-15. PubMed ID: 22068567
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genetic analysis of heterogeneous sub-clones in recombinant Chinese hamster ovary cells.
    Chen K; Li D; Li H; Li B; Li J; Huang L; Li R; Xu X; Jiang L; Jiang C; Gu H; Fang J
    Appl Microbiol Biotechnol; 2017 Jul; 101(14):5785-5797. PubMed ID: 28540426
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Early prediction of instability of Chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins.
    Dorai H; Corisdeo S; Ellis D; Kinney C; Chomo M; Hawley-Nelson P; Moore G; Betenbaugh MJ; Ganguly S
    Biotechnol Bioeng; 2012 Apr; 109(4):1016-30. PubMed ID: 22068683
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Bioinformatics Pipeline for the Identification of CHO Cell Differential Gene Expression from RNA-Seq Data.
    Monger C; Motheramgari K; McSharry J; Barron N; Clarke C
    Methods Mol Biol; 2017; 1603():169-186. PubMed ID: 28493130
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Highly efficient deletion of FUT8 in CHO cell lines using zinc-finger nucleases yields cells that produce completely nonfucosylated antibodies.
    Malphettes L; Freyvert Y; Chang J; Liu PQ; Chan E; Miller JC; Zhou Z; Nguyen T; Tsai C; Snowden AW; Collingwood TN; Gregory PD; Cost GJ
    Biotechnol Bioeng; 2010 Aug; 106(5):774-83. PubMed ID: 20564614
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bioreactor scale up and protein product quality characterization of piggyBac transposon derived CHO pools.
    Rajendra Y; Balasubramanian S; Peery RB; Swartling JR; McCracken NA; Norris DL; Frye CC; Barnard GC
    Biotechnol Prog; 2017 Mar; 33(2):534-540. PubMed ID: 28188692
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An RNA-seq based transcriptomic investigation into the productivity and growth variants with Chinese hamster ovary cells.
    Sha S; Bhatia H; Yoon S
    J Biotechnol; 2018 Apr; 271():37-46. PubMed ID: 29476805
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Towards next generation CHO cell biology: Bioinformatics methods for RNA-Seq-based expression profiling.
    Monger C; Kelly PS; Gallagher C; Clynes M; Barron N; Clarke C
    Biotechnol J; 2015 Jul; 10(7):950-66. PubMed ID: 26058739
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells.
    Loh WP; Loo B; Zhou L; Zhang P; Lee DY; Yang Y; Lam KP
    Biotechnol J; 2014 Sep; 9(9):1140-51. PubMed ID: 24819042
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A global RNA-seq-driven analysis of CHO host and production cell lines reveals distinct differential expression patterns of genes contributing to recombinant antibody glycosylation.
    Könitzer JD; Müller MM; Leparc G; Pauers M; Bechmann J; Schulz P; Schaub J; Enenkel B; Hildebrandt T; Hampel M; Tolstrup AB
    Biotechnol J; 2015 Sep; 10(9):1412-23. PubMed ID: 26212696
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chinese hamster ovary K1 host cell enables stable cell line development for antibody molecules which are difficult to express in DUXB11-derived dihydrofolate reductase deficient host cell.
    Hu Z; Guo D; Yip SS; Zhan D; Misaghi S; Joly JC; Snedecor BR; Shen AY
    Biotechnol Prog; 2013; 29(4):980-5. PubMed ID: 23606666
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells.
    Kelly PS; Clarke C; Costello A; Monger C; Meiller J; Dhiman H; Borth N; Betenbaugh MJ; Clynes M; Barron N
    Metab Eng; 2017 May; 41():11-22. PubMed ID: 28188893
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.