135 related articles for article (PubMed ID: 29316330)
21. Reduction of ammonia and lactate through the coupling of glutamine synthetase selection and downregulation of lactate dehydrogenase-A in CHO cells.
Noh SM; Park JH; Lim MS; Kim JW; Lee GM
Appl Microbiol Biotechnol; 2017 Feb; 101(3):1035-1045. PubMed ID: 27704181
[TBL] [Abstract][Full Text] [Related]
22. Heat shock protein 27 overexpression in CHO cells modulates apoptosis pathways and delays activation of caspases to improve recombinant monoclonal antibody titre in fed-batch bioreactors.
Tan JG; Lee YY; Wang T; Yap MG; Tan TW; Ng SK
Biotechnol J; 2015 May; 10(5):790-800. PubMed ID: 25740626
[TBL] [Abstract][Full Text] [Related]
23. Proteomic analysis of CHO cell lines producing high and low quantities of a recombinant antibody before and after selection with methotrexate.
Hausmann R; Chudobová I; Spiegel H; Schillberg S
J Biotechnol; 2018 Jan; 265():65-69. PubMed ID: 29137976
[TBL] [Abstract][Full Text] [Related]
24. Tracing production instability in a clonally derived CHO cell line using single-cell transcriptomics.
Tzani I; Herrmann N; Carillo S; Spargo CA; Hagan R; Barron N; Bones J; Shannon Dillmore W; Clarke C
Biotechnol Bioeng; 2021 May; 118(5):2016-2030. PubMed ID: 33586781
[TBL] [Abstract][Full Text] [Related]
25. Auditioning of CHO host cell lines using the artificial chromosome expression (ACE) technology.
Kennard ML; Goosney DL; Monteith D; Roe S; Fischer D; Mott J
Biotechnol Bioeng; 2009 Oct; 104(3):526-39. PubMed ID: 19544304
[TBL] [Abstract][Full Text] [Related]
26. miRNA profiling of high, low and non-producing CHO cells during biphasic fed-batch cultivation reveals process relevant targets for host cell engineering.
Stiefel F; Fischer S; Sczyrba A; Otte K; Hesse F
J Biotechnol; 2016 May; 225():31-43. PubMed ID: 27002234
[TBL] [Abstract][Full Text] [Related]
27. Carboxypeptidase D is the only enzyme responsible for antibody C-terminal lysine cleavage in Chinese hamster ovary (CHO) cells.
Hu Z; Zhang H; Haley B; Macchi F; Yang F; Misaghi S; Elich J; Yang R; Tang Y; Joly JC; Snedecor BR; Shen A
Biotechnol Bioeng; 2016 Oct; 113(10):2100-6. PubMed ID: 26989081
[TBL] [Abstract][Full Text] [Related]
28. Changes in Chromosome Counts and Patterns in CHO Cell Lines upon Generation of Recombinant Cell Lines and Subcloning.
Vcelar S; Melcher M; Auer N; Hrdina A; Puklowski A; Leisch F; Jadhav V; Wenger T; Baumann M; Borth N
Biotechnol J; 2018 Mar; 13(3):e1700495. PubMed ID: 29328552
[TBL] [Abstract][Full Text] [Related]
29. Identifying low-level sequence variants via next generation sequencing to aid stable CHO cell line screening.
Zhang S; Bartkowiak L; Nabiswa B; Mishra P; Fann J; Ouellette D; Correia I; Regier D; Liu J
Biotechnol Prog; 2015; 31(4):1077-85. PubMed ID: 26033952
[TBL] [Abstract][Full Text] [Related]
30. Characterization of cellular states of CHO-K1 suspension cell culture through cell cycle and RNA-sequencing profiling.
Tossolini I; López-Díaz FJ; Kratje R; Prieto CC
J Biotechnol; 2018 Nov; 286():56-67. PubMed ID: 30243609
[TBL] [Abstract][Full Text] [Related]
31. Applications of low-intensity pulsed ultrasound to increase monoclonal antibody production in CHO cells using shake flasks or wavebags.
Zhao Y; Xing J; Xing JZ; Ang WT; Chen J
Ultrasonics; 2014 Aug; 54(6):1439-47. PubMed ID: 24841953
[TBL] [Abstract][Full Text] [Related]
32. A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies.
Kim M; O'Callaghan PM; Droms KA; James DC
Biotechnol Bioeng; 2011 Oct; 108(10):2434-46. PubMed ID: 21538334
[TBL] [Abstract][Full Text] [Related]
33. Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells.
Figueroa B; Ailor E; Osborne D; Hardwick JM; Reff M; Betenbaugh MJ
Biotechnol Bioeng; 2007 Jul; 97(4):877-92. PubMed ID: 17099908
[TBL] [Abstract][Full Text] [Related]
34. Production of monoclonal antibodies in COS and CHO cells.
Trill JJ; Shatzman AR; Ganguly S
Curr Opin Biotechnol; 1995 Oct; 6(5):553-60. PubMed ID: 7579667
[TBL] [Abstract][Full Text] [Related]
35. Development of a highly-efficient CHO cell line generation system with engineered SV40E promoter.
Fan L; Kadura I; Krebs LE; Larson JL; Bowden DM; Frye CC
J Biotechnol; 2013 Dec; 168(4):652-8. PubMed ID: 23994266
[TBL] [Abstract][Full Text] [Related]
36. An automated RNA-Seq analysis pipeline to identify and visualize differentially expressed genes and pathways in CHO cells.
Chen C; Le H; Goudar CT
Biotechnol Prog; 2015; 31(5):1150-62. PubMed ID: 26150012
[TBL] [Abstract][Full Text] [Related]
37. Optimized Selection Marker and CHO Host Cell Combinations for Generating High Monoclonal Antibody Producing Cell Lines.
Yeo JHM; Ho SCL; Mariati M; Koh E; Tay SJ; Woen S; Zhang P; Yang Y
Biotechnol J; 2017 Dec; 12(12):. PubMed ID: 29090854
[TBL] [Abstract][Full Text] [Related]
38. ATF6β-based fine-tuning of the unfolded protein response enhances therapeutic antibody productivity of Chinese hamster ovary cells.
Pieper LA; Strotbek M; Wenger T; Olayioye MA; Hausser A
Biotechnol Bioeng; 2017 Jun; 114(6):1310-1318. PubMed ID: 28165157
[TBL] [Abstract][Full Text] [Related]
39. Functional heterogeneity and heritability in CHO cell populations.
Davies SL; Lovelady CS; Grainger RK; Racher AJ; Young RJ; James DC
Biotechnol Bioeng; 2013 Jan; 110(1):260-74. PubMed ID: 22833427
[TBL] [Abstract][Full Text] [Related]
40. Deletion of a telomeric region on chromosome 8 correlates with higher productivity and stability of CHO cell lines.
Ritter A; Voedisch B; Wienberg J; Wilms B; Geisse S; Jostock T; Laux H
Biotechnol Bioeng; 2016 May; 113(5):1084-93. PubMed ID: 26523402
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
