BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 29316361)

  • 1. Effects of serum, enzyme, thiol, and forced degradation on the stabilities of αO-Conotoxin GeXIVA[1,2] and GeXIVA [1,4].
    Yu S; Wu Y; Xu P; Wang S; Zhangsun D; Luo S
    Chem Biol Drug Des; 2018 May; 91(5):1030-1041. PubMed ID: 29316361
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure and Activity Studies of Disulfide-Deficient Analogues of αO-Conotoxin GeXIVA.
    Xu P; Kaas Q; Wu Y; Zhu X; Li X; Harvey PJ; Zhangsun D; Craik DJ; Luo S
    J Med Chem; 2020 Feb; 63(4):1564-1575. PubMed ID: 31986036
    [TBL] [Abstract][Full Text] [Related]  

  • 3. αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype.
    Zhangsun D; Zhu X; Kaas Q; Wu Y; Craik DJ; McIntosh JM; Luo S
    Neuropharmacology; 2017 Dec; 127():243-252. PubMed ID: 28416445
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.
    Luo S; Zhangsun D; Harvey PJ; Kaas Q; Wu Y; Zhu X; Hu Y; Li X; Tsetlin VI; Christensen S; Romero HK; McIntyre M; Dowell C; Baxter JC; Elmslie KS; Craik DJ; McIntosh JM
    Proc Natl Acad Sci U S A; 2015 Jul; 112(30):E4026-35. PubMed ID: 26170295
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-Activity Relationships of Alanine Scan Mutants αO-Conotoxins GeXIVA[1,2] and GeXIVA[1,4].
    Xu P; Zhang P; Zhu X; Wu Y; Harvey PJ; Kaas Q; Zhangsun D; Craik DJ; Luo S
    J Med Chem; 2023 Jul; 66(14):10092-10107. PubMed ID: 37464764
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models.
    Kryukova EV; Ivanov IA; Lebedev DS; Spirova EN; Egorova NS; Zouridakis M; Kasheverov IE; Tzartos SJ; Tsetlin VI
    Mar Drugs; 2018 Nov; 16(12):. PubMed ID: 30469507
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aspartic acid mutagenesis of αO-Conotoxin GeXIVA isomers reveals arginine residues crucial for inhibition of the α9α10 nicotinic acetylcholine receptor.
    Luo A; He J; Yu J; Wu Y; Harvey PJ; Kasheverov IE; Kudryavtsev DS; McIntosh JM; Tsetlin VI; Craik DJ; Zhangsun D; Luo S
    Int J Biol Macromol; 2024 May; ():132472. PubMed ID: 38772455
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-hypersensitive effect of intramuscular administration of αO-conotoxin GeXIVA[1,2] and GeXIVA[1,4] in rats of neuropathic pain.
    Li X; Hu Y; Wu Y; Huang Y; Yu S; Ding Q; Zhangsun D; Luo S
    Prog Neuropsychopharmacol Biol Psychiatry; 2016 Apr; 66():112-119. PubMed ID: 26706456
    [TBL] [Abstract][Full Text] [Related]  

  • 9. αO-Conotoxin GeXIVA Inhibits the Growth of Breast Cancer Cells via Interaction with α9 Nicotine Acetylcholine Receptors.
    Sun Z; Bao J; Zhangsun M; Dong S; Zhangsun D; Luo S
    Mar Drugs; 2020 Apr; 18(4):. PubMed ID: 32272701
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The α9α10 Nicotinic Acetylcholine Receptor Antagonist αO-Conotoxin GeXIVA[1,2] Alleviates and Reverses Chemotherapy-Induced Neuropathic Pain.
    Wang H; Li X; Zhangsun D; Yu G; Su R; Luo S
    Mar Drugs; 2019 May; 17(5):. PubMed ID: 31060282
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer.
    Wu X; Huang YH; Kaas Q; Harvey PJ; Wang CK; Tae HS; Adams DJ; Craik DJ
    J Biol Chem; 2017 Oct; 292(41):17101-17112. PubMed ID: 28851841
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ɑO-Conotoxin GeXIVA isomers modulate N-type calcium (Ca
    Yousuf A; Wu X; Bony AR; Sadeghi M; Huang YH; Craik DJ; Adams DJ
    J Neurochem; 2022 Jan; 160(2):154-171. PubMed ID: 34738241
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential Expression of Nicotine Acetylcholine Receptors Associates with Human Breast Cancer and Mediates Antitumor Activity of αO-Conotoxin GeXIVA.
    Sun Z; Zhangsun M; Dong S; Liu Y; Qian J; Zhangsun D; Luo S
    Mar Drugs; 2020 Jan; 18(1):. PubMed ID: 31963558
    [TBL] [Abstract][Full Text] [Related]  

  • 14. αO-Conotoxin GeXIVA[1,2] Reduced Neuropathic Pain and Changed Gene Expression in Chronic Oxaliplatin-Induced Neuropathy Mice Model.
    Wang H; Li X; Qiao Y; Wang M; Wang W; McIntosh JM; Zhangsun D; Luo S
    Mar Drugs; 2024 Jan; 22(1):. PubMed ID: 38276651
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lyophilization Serves as an Effective Strategy for Drug Development of the α9α10 Nicotinic Acetylcholine Receptor Antagonist α-Conotoxin GeXIVA[1,2].
    Li Z; Han X; Hong X; Li X; Gao J; Zhang H; Zheng A
    Mar Drugs; 2021 Feb; 19(3):. PubMed ID: 33668830
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel αO-conotoxin GeXIVA[1,2] Nonaddictive Analgesic with Pharmacokinetic Modelling-Based Mechanistic Assessment.
    Zhu X; Yuan M; Wang H; Zhangsun D; Yu G; Che J; Luo S
    Pharmaceutics; 2022 Aug; 14(9):. PubMed ID: 36145535
    [TBL] [Abstract][Full Text] [Related]  

  • 17. d-Amino Acid Substitution of α-Conotoxin RgIA Identifies its Critical Residues and Improves the Enzymatic Stability.
    Ren J; Zhu X; Xu P; Li R; Fu Y; Dong S; Zhangsun D; Wu Y; Luo S
    Mar Drugs; 2019 Feb; 17(3):. PubMed ID: 30823399
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human α9α10 Nicotinic Acetylcholine Receptor.
    Jiang S; Tae HS; Xu S; Shao X; Adams DJ; Wang C
    Mar Drugs; 2017 Jun; 15(6):. PubMed ID: 28598389
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dual Antagonism of α9α10 nAChR and GABA
    Li X; Tae HS; Chen S; Yousuf A; Huang L; Zhang J; Jiang T; Adams DJ; Yu R
    J Med Chem; 2024 Jan; 67(2):971-987. PubMed ID: 38217860
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?
    Mohammadi SA; Christie MJ
    Toxins (Basel); 2015 Sep; 7(10):3916-32. PubMed ID: 26426047
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.