BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 29319363)

  • 1. Expression of serglycin in human disc is increased in degenerated discs and up-regulated in vitro by exposure to IL-1ß or TNF-α.
    Gruber HE; Hanley EN
    Biotech Histochem; 2018; 93(2):109-117. PubMed ID: 29319363
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Increased IL-17 expression in degenerated human discs and increased production in cultured annulus cells exposed to IL-1ß and TNF-α.
    Gruber HE; Hoelscher GL; Ingram JA; Norton HJ; Hanley EN
    Biotech Histochem; 2013 Aug; 88(6):302-10. PubMed ID: 23627571
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mucin 1, a signal transduction membrane-bound mucin, is present in human disc tissue and is downregulated in vitro by exposure to IL-1ß or TNF-α.
    Gruber HE; Ingram JA; Hoelscher GL; Marrero E; Hanley EN
    BMC Musculoskelet Disord; 2017 May; 18(1):182. PubMed ID: 28482827
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interleukin-23 is constitutively expressed in the human annulus in vivo and in vitro, and is up-regulated in vitro by TNF-α.
    Gruber HE; Marrero E; Cox M; Hanley E
    Biotech Histochem; 2019 Oct; 94(7):540-545. PubMed ID: 31537133
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Autophagy in the Degenerating Human Intervertebral Disc: In Vivo Molecular and Morphological Evidence, and Induction of Autophagy in Cultured Annulus Cells Exposed to Proinflammatory Cytokines-Implications for Disc Degeneration.
    Gruber HE; Hoelscher GL; Ingram JA; Bethea S; Hanley EN
    Spine (Phila Pa 1976); 2015 Jun; 40(11):773-82. PubMed ID: 26091153
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High-mobility group box-1 gene, a potent proinflammatory mediators, is upregulated in more degenerated human discs in vivo and its receptor upregulated by TNF-α exposure in vitro.
    Gruber HE; Hoelscher GL; Bethea S; Ingram J; Cox M; Hanley EN
    Exp Mol Pathol; 2015 Jun; 98(3):427-30. PubMed ID: 25746662
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The chemokine, CXCL16, and its receptor, CXCR6, are constitutively expressed in human annulus fibrosus and expression of CXCL16 is up-regulated by exposure to IL-1ß in vitro.
    Gruber HE; Marrero E; Ingram JA; Hoelscher GL; Hanley EN
    Biotech Histochem; 2017; 92(1):7-14. PubMed ID: 27869573
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Growth and differentiation factor-5 (GDF-5) in the human intervertebral annulus cells and its modulation by IL-1ß and TNF-α in vitro.
    Gruber HE; Hoelscher GL; Ingram JA; Bethea S; Hanley EN
    Exp Mol Pathol; 2014 Apr; 96(2):225-9. PubMed ID: 24582800
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The anabolic effect of plasma-mediated ablation on the intervertebral disc: stimulation of proteoglycan and interleukin-8 production.
    Kuelling FA; Foley KT; Liu JJ; Liebenberg E; Sin AH; Matsukawa A; Lotz JC
    Spine J; 2014 Oct; 14(10):2479-87. PubMed ID: 24747799
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Constitutive expression of IL-22 in the human intervertebral disc and its reduction by exposure to pro-inflammatory cytokines in vitro.
    Gruber HE; Marrero E; Ingram JA; Hoelscher GL; Hanley EN
    Biotech Histochem; 2017; 92(3):222-229. PubMed ID: 28409653
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Proinflammatory Cytokines IL-1β and TNF-α Influence Human Annulus Cell Signaling Cues for Neurite Growth: In Vitro Coculture Studies.
    Gruber HE; Jones B; Marrero E; Hanley EN
    Spine (Phila Pa 1976); 2017 Oct; 42(20):1529-1537. PubMed ID: 28306638
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proinflammatory cytokines modulate the chemokine CCL2 (MCP-1) in human annulus cells in vitro: CCL2 expression and production.
    Gruber HE; Hoelscher GL; Ingram JA; Bethea S; Cox M; Hanley EN
    Exp Mol Pathol; 2015 Feb; 98(1):102-5. PubMed ID: 25527176
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Production and expression of RANTES (CCL5) by human disc cells and modulation by IL-1-β and TNF-α in 3D culture.
    Gruber HE; Hoelscher GL; Ingram JA; Bethea S; Norton HJ; Hanley EN
    Exp Mol Pathol; 2014 Apr; 96(2):133-8. PubMed ID: 24468005
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparative expression of matrix-associated genes and inflammatory cytokines-associated genes according to disc degeneration: analysis of living human nucleus pulposus.
    Park JY; Kuh SU; Park HS; Kim KS
    J Spinal Disord Tech; 2011 Aug; 24(6):352-7. PubMed ID: 21150669
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression and relationship of proinflammatory chemokine RANTES/CCL5 and cytokine IL-1β in painful human intervertebral discs.
    Kepler CK; Markova DZ; Dibra F; Yadla S; Vaccaro AR; Risbud MV; Albert TJ; Anderson DG
    Spine (Phila Pa 1976); 2013 May; 38(11):873-80. PubMed ID: 23660804
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of kartogenin on the attenuated nucleus pulposus cell degeneration of intervertebral discs induced by interleukin-1β and tumor necrosis factor-α.
    Huang Y; Jiang T; Chen J; Yin GY; Fan J
    Int J Mol Med; 2018 Feb; 41(2):749-756. PubMed ID: 29207013
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human nucleus pulposus cells react to IL-6: independent actions and amplification of response to IL-1 and TNF-α.
    Studer RK; Vo N; Sowa G; Ondeck C; Kang J
    Spine (Phila Pa 1976); 2011 Apr; 36(8):593-9. PubMed ID: 21178846
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitochondrial Membrane Potential and Nuclear and Gene Expression Changes During Human Disc Cell Apoptosis: In Vitro and In Vivo Annulus Findings.
    Gruber HE; Hoelscher GL; Bethea S; Hanley EN
    Spine (Phila Pa 1976); 2015 Jun; 40(12):876-82. PubMed ID: 25909354
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Capability of nondegenerated and degenerated discs in producing inflammatory agents with or without macrophage interaction.
    Hamamoto H; Miyamoto H; Doita M; Takada T; Nishida K; Kurosaka M
    Spine (Phila Pa 1976); 2012 Feb; 37(3):161-7. PubMed ID: 21494199
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cortistatin is endogenous to the human intervertebral disc and exerts in vitro mitogenic effects on annulus cells and a downregulatory effect on TNF-α expression.
    Gruber HE; Hoelscher GL; Bethea SF; Menscher EA; Ingram JA; Templin MA; Hanley EN
    Spine J; 2014 Dec; 14(12):2995-3001. PubMed ID: 24912122
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.