BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

372 related articles for article (PubMed ID: 29327083)

  • 1. R-loops: targets for nuclease cleavage and repeat instability.
    Freudenreich CH
    Curr Genet; 2018 Aug; 64(4):789-794. PubMed ID: 29327083
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytosine deamination and base excision repair cause R-loop-induced CAG repeat fragility and instability in
    Su XA; Freudenreich CH
    Proc Natl Acad Sci U S A; 2017 Oct; 114(40):E8392-E8401. PubMed ID: 28923949
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Processing of double-R-loops in (CAG)·(CTG) and C9orf72 (GGGGCC)·(GGCCCC) repeats causes instability.
    Reddy K; Schmidt MH; Geist JM; Thakkar NP; Panigrahi GB; Wang YH; Pearson CE
    Nucleic Acids Res; 2014; 42(16):10473-87. PubMed ID: 25147206
    [TBL] [Abstract][Full Text] [Related]  

  • 4. R loops stimulate genetic instability of CTG.CAG repeats.
    Lin Y; Dent SY; Wilson JH; Wells RD; Napierala M
    Proc Natl Acad Sci U S A; 2010 Jan; 107(2):692-7. PubMed ID: 20080737
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Double-strand break repair pathways protect against CAG/CTG repeat expansions, contractions and repeat-mediated chromosomal fragility in Saccharomyces cerevisiae.
    Sundararajan R; Gellon L; Zunder RM; Freudenreich CH
    Genetics; 2010 Jan; 184(1):65-77. PubMed ID: 19901069
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RNA-DNA hybrids promote the expansion of Friedreich's ataxia (GAA)n repeats via break-induced replication.
    Neil AJ; Liang MU; Khristich AN; Shah KA; Mirkin SM
    Nucleic Acids Res; 2018 Apr; 46(7):3487-3497. PubMed ID: 29447396
    [TBL] [Abstract][Full Text] [Related]  

  • 7. R-loops promote trinucleotide repeat deletion through DNA base excision repair enzymatic activities.
    Laverde EE; Lai Y; Leng F; Balakrishnan L; Freudenreich CH; Liu Y
    J Biol Chem; 2020 Oct; 295(40):13902-13913. PubMed ID: 32763971
    [TBL] [Abstract][Full Text] [Related]  

  • 8. R-loops as Janus-faced modulators of DNA repair.
    Marnef A; Legube G
    Nat Cell Biol; 2021 Apr; 23(4):305-313. PubMed ID: 33837288
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Disease-associated repeat instability and mismatch repair.
    Schmidt MHM; Pearson CE
    DNA Repair (Amst); 2016 Feb; 38():117-126. PubMed ID: 26774442
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-forming CAG/CTG repeat sequences are sensitive to breakage in the absence of Mrc1 checkpoint function and S-phase checkpoint signaling: implications for trinucleotide repeat expansion diseases.
    Freudenreich CH; Lahiri M
    Cell Cycle; 2004 Nov; 3(11):1370-4. PubMed ID: 15483399
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner.
    Yang J; Freudenreich CH
    Gene; 2007 May; 393(1-2):110-5. PubMed ID: 17383831
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Flap Endonuclease 1 Endonucleolytically Processes RNA to Resolve R-Loops through DNA Base Excision Repair.
    Laverde EE; Polyzos AA; Tsegay PP; Shaver M; Hutcheson JD; Balakrishnan L; McMurray CT; Liu Y
    Genes (Basel); 2022 Dec; 14(1):. PubMed ID: 36672839
    [TBL] [Abstract][Full Text] [Related]  

  • 13. On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability.
    Khristich AN; Mirkin SM
    J Biol Chem; 2020 Mar; 295(13):4134-4170. PubMed ID: 32060097
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Restarted replication forks are error-prone and cause CAG repeat expansions and contractions.
    Gold MA; Whalen JM; Freon K; Hong Z; Iraqui I; Lambert SAE; Freudenreich CH
    PLoS Genet; 2021 Oct; 17(10):e1009863. PubMed ID: 34673780
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice.
    Goula AV; Berquist BR; Wilson DM; Wheeler VC; Trottier Y; Merienne K
    PLoS Genet; 2009 Dec; 5(12):e1000749. PubMed ID: 19997493
    [TBL] [Abstract][Full Text] [Related]  

  • 16. R-Loop Physiology and Pathology: A Brief Review.
    Mackay RP; Xu Q; Weinberger PM
    DNA Cell Biol; 2020 Nov; 39(11):1914-1925. PubMed ID: 33052725
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Replication stress at microsatellites causes DNA double-strand breaks and break-induced replication.
    Gadgil RY; Romer EJ; Goodman CC; Rider SD; Damewood FJ; Barthelemy JR; Shin-Ya K; Hanenberg H; Leffak M
    J Biol Chem; 2020 Nov; 295(45):15378-15397. PubMed ID: 32873711
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tracking Expansions of Stable and Threshold Length Trinucleotide Repeat Tracts In Vivo and In Vitro Using Saccharomyces cerevisiae.
    Williams GM; Petrides AK; Balakrishnan L; Surtees JA
    Methods Mol Biol; 2020; 2056():25-68. PubMed ID: 31586340
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nucleotide excision repair, mismatch repair, and R-loops modulate convergent transcription-induced cell death and repeat instability.
    Lin Y; Wilson JH
    PLoS One; 2012; 7(10):e46807. PubMed ID: 23056461
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New insights into repeat instability: role of RNA•DNA hybrids.
    McIvor EI; Polak U; Napierala M
    RNA Biol; 2010; 7(5):551-8. PubMed ID: 20729633
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.