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2. Prevention of tau increase in cerebrospinal fluid of APP transgenic mice suggests downstream effect of BACE1 inhibition. Schelle J; Häsler LM; Göpfert JC; Joos TO; Vanderstichele H; Stoops E; Mandelkow EM; Neumann U; Shimshek DR; Staufenbiel M; Jucker M; Kaeser SA Alzheimers Dement; 2017 Jun; 13(6):701-709. PubMed ID: 27750032 [TBL] [Abstract][Full Text] [Related]
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5. Tau deletion reduces plaque-associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease. Peters F; Salihoglu H; Pratsch K; Herzog E; Pigoni M; Sgobio C; Lichtenthaler SF; Neumann U; Herms J EMBO J; 2019 Dec; 38(23):e102345. PubMed ID: 31701556 [TBL] [Abstract][Full Text] [Related]
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9. Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development. Zhang XM; Cai Y; Xiong K; Cai H; Luo XG; Feng JC; Clough RW; Struble RG; Patrylo PR; Yan XX Eur J Neurosci; 2009 Dec; 30(12):2271-83. PubMed ID: 20092570 [TBL] [Abstract][Full Text] [Related]
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13. Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer's disease transgenic mice. Kimura R; Devi L; Ohno M J Neurochem; 2010 Apr; 113(1):248-61. PubMed ID: 20089133 [TBL] [Abstract][Full Text] [Related]
14. Centrally Delivered BACE1 Inhibitor Activates Microglia, and Reverses Amyloid Pathology and Cognitive Deficit in Aged Tg2576 Mice. Thakker DR; Sankaranarayanan S; Weatherspoon MR; Harrison J; Pierdomenico M; Heisel JM; Thompson LA; Haskell R; Grace JE; Taylor SJ; Albright CF; Shafer LL J Neurosci; 2015 Apr; 35(17):6931-6. PubMed ID: 25926467 [TBL] [Abstract][Full Text] [Related]
15. Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. O'Connor T; Sadleir KR; Maus E; Velliquette RA; Zhao J; Cole SL; Eimer WA; Hitt B; Bembinster LA; Lammich S; Lichtenthaler SF; Hébert SS; De Strooper B; Haass C; Bennett DA; Vassar R Neuron; 2008 Dec; 60(6):988-1009. PubMed ID: 19109907 [TBL] [Abstract][Full Text] [Related]
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17. Astragaloside IV, a Natural PPARγ Agonist, Reduces Aβ Production in Alzheimer's Disease Through Inhibition of BACE1. Wang X; Wang Y; Hu JP; Yu S; Li BK; Cui Y; Ren L; Zhang LD Mol Neurobiol; 2017 May; 54(4):2939-2949. PubMed ID: 27023226 [TBL] [Abstract][Full Text] [Related]
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20. The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity. Hook G; Hook V; Kindy M J Alzheimers Dis; 2011; 26(2):387-408. PubMed ID: 21613740 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]