These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

502 related articles for article (PubMed ID: 29329228)

  • 21. Fragment-Based Drug Discovery: Advancing Fragments in the Absence of Crystal Structures.
    Erlanson DA; Davis BJ; Jahnke W
    Cell Chem Biol; 2019 Jan; 26(1):9-15. PubMed ID: 30482678
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hot-Spotting with Thermal Scanning: A Ligand- and Structure-Independent Assessment of Target Ligandability.
    Chilton M; Clennell B; Edfeldt F; Geschwindner S
    J Med Chem; 2017 Jun; 60(12):4923-4931. PubMed ID: 28537726
    [TBL] [Abstract][Full Text] [Related]  

  • 23. NMR in drug discovery.
    Pellecchia M; Sem DS; Wüthrich K
    Nat Rev Drug Discov; 2002 Mar; 1(3):211-9. PubMed ID: 12120505
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Design of small molecule libraries for NMR screening and other applications in drug discovery.
    Jacoby E; Davies J; Blommers MJ
    Curr Top Med Chem; 2003; 3(1):11-23. PubMed ID: 12570776
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Applications of In-Cell NMR in Structural Biology and Drug Discovery.
    Kang C
    Int J Mol Sci; 2019 Jan; 20(1):. PubMed ID: 30609728
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Fragment-Linking Approach Using (19)F NMR Spectroscopy To Obtain Highly Potent and Selective Inhibitors of β-Secretase.
    Jordan JB; Whittington DA; Bartberger MD; Sickmier EA; Chen K; Cheng Y; Judd T
    J Med Chem; 2016 Apr; 59(8):3732-49. PubMed ID: 26978477
    [TBL] [Abstract][Full Text] [Related]  

  • 27. NMR screening and hit validation in fragment based drug discovery.
    Campos-Olivas R
    Curr Top Med Chem; 2011; 11(1):43-67. PubMed ID: 20809889
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A drug discovery toolbox for Nuclear Magnetic Resonance (NMR) characterization of ligands and their targets.
    LeBlanc RM; Mesleh MF
    Drug Discov Today Technol; 2020 Dec; 37():51-60. PubMed ID: 34895655
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Efficient affinity ranking of fluorinated ligands by
    Rüdisser SH; Goldberg N; Ebert MO; Kovacs H; Gossert AD
    J Biomol NMR; 2020 Nov; 74(10-11):579-594. PubMed ID: 32556806
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Technological advances in high-throughput screening.
    Liu B; Li S; Hu J
    Am J Pharmacogenomics; 2004; 4(4):263-76. PubMed ID: 15287820
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Alternate strategies to obtain mass balance without the use of radiolabeled compounds: application of quantitative fluorine (19F) nuclear magnetic resonance (NMR) spectroscopy in metabolism studies.
    Mutlib A; Espina R; Atherton J; Wang J; Talaat R; Scatina J; Chandrasekaran A
    Chem Res Toxicol; 2012 Mar; 25(3):572-83. PubMed ID: 22292524
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Advancing fragment binders to lead-like compounds using ligand and protein-based NMR spectroscopy.
    Maurer T
    Methods Enzymol; 2011; 493():469-85. PubMed ID: 21371602
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Paramagnetic NMR in drug discovery.
    Softley CA; Bostock MJ; Popowicz GM; Sattler M
    J Biomol NMR; 2020 Jul; 74(6-7):287-309. PubMed ID: 32524233
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Nuclear magnetic resonance in target profiling and compound file enhancement.
    Sun C; Hajduk PJ
    Curr Opin Drug Discov Devel; 2006 Jul; 9(4):463-70. PubMed ID: 16889229
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A Practical Perspective on the Roles of Solution NMR Spectroscopy in Drug Discovery.
    Li Q; Kang C
    Molecules; 2020 Jun; 25(13):. PubMed ID: 32605297
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Application of NMR screening in drug discovery.
    Fejzo J; Lepre C; Xie X
    Curr Top Med Chem; 2003; 3(1):81-97. PubMed ID: 12570779
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The application of absolute quantitative (1)H NMR spectroscopy in drug discovery and development.
    Singh S; Roy R
    Expert Opin Drug Discov; 2016 Jul; 11(7):695-706. PubMed ID: 27187052
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Fragment-based activity space: smaller is better.
    Hesterkamp T; Whittaker M
    Curr Opin Chem Biol; 2008 Jun; 12(3):260-8. PubMed ID: 18316043
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Utilizing 19F NMR to investigate drug disposition early in drug discovery.
    Hu H; Huang N; Yi P; Hui YH; Dally RD; Ehlhardt WJ; Kulanthaivel P
    Xenobiotica; 2015; 45(12):1081-91. PubMed ID: 25946562
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Discovery of ligands for Nurr1 by combined use of NMR screening with different isotopic and spin-labeling strategies.
    Poppe L; Harvey TS; Mohr C; Zondlo J; Tegley CM; Nuanmanee O; Cheetham J
    J Biomol Screen; 2007 Apr; 12(3):301-11. PubMed ID: 17438066
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 26.