365 related articles for article (PubMed ID: 29329425)
1. Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study.
Bell CC; Dankers ACA; Lauschke VM; Sison-Young R; Jenkins R; Rowe C; Goldring CE; Park K; Regan SL; Walker T; Schofield C; Baze A; Foster AJ; Williams DP; van de Ven AWM; Jacobs F; Houdt JV; Lähteenmäki T; Snoeys J; Juhila S; Richert L; Ingelman-Sundberg M
Toxicol Sci; 2018 Apr; 162(2):655-666. PubMed ID: 29329425
[TBL] [Abstract][Full Text] [Related]
2. Inter-individual differences in the susceptibility of primary human hepatocytes towards drug-induced cholestasis are compound and time dependent.
Parmentier C; Hendriks DFG; Heyd B; Bachellier P; Ingelman-Sundberg M; Richert L
Toxicol Lett; 2018 Oct; 295():187-194. PubMed ID: 29913214
[TBL] [Abstract][Full Text] [Related]
3. Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions.
Vorrink SU; Zhou Y; Ingelman-Sundberg M; Lauschke VM
Toxicol Sci; 2018 Jun; 163(2):655-665. PubMed ID: 29590495
[TBL] [Abstract][Full Text] [Related]
4. Three-Dimensional Spheroid Primary Human Hepatocytes in Monoculture and Coculture with Nonparenchymal Cells.
Baze A; Parmentier C; Hendriks DFG; Hurrell T; Heyd B; Bachellier P; Schuster C; Ingelman-Sundberg M; Richert L
Tissue Eng Part C Methods; 2018 Sep; 24(9):534-545. PubMed ID: 30101670
[TBL] [Abstract][Full Text] [Related]
5. Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease.
Bell CC; Hendriks DF; Moro SM; Ellis E; Walsh J; Renblom A; Fredriksson Puigvert L; Dankers AC; Jacobs F; Snoeys J; Sison-Young RL; Jenkins RE; Nordling Å; Mkrtchian S; Park BK; Kitteringham NR; Goldring CE; Lauschke VM; Ingelman-Sundberg M
Sci Rep; 2016 May; 6():25187. PubMed ID: 27143246
[TBL] [Abstract][Full Text] [Related]
6. Chemical-based primary human hepatocyte monolayer culture for the study of drug metabolism and hepatotoxicity: Comparison with the spheroid model.
Zhong Y; Yu JS; Wang X; Binas B; Yoo HH
FASEB J; 2021 Mar; 35(3):e21379. PubMed ID: 33566373
[TBL] [Abstract][Full Text] [Related]
7. Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation.
Rubiano A; Indapurkar A; Yokosawa R; Miedzik A; Rosenzweig B; Arefin A; Moulin CM; Dame K; Hartman N; Volpe DA; Matta MK; Hughes DJ; Strauss DG; Kostrzewski T; Ribeiro AJS
Clin Transl Sci; 2021 May; 14(3):1049-1061. PubMed ID: 33382907
[TBL] [Abstract][Full Text] [Related]
8. HepaRG culture in tethered spheroids as an in vitro three-dimensional model for drug safety screening.
Wang Z; Luo X; Anene-Nzelu C; Yu Y; Hong X; Singh NH; Xia L; Liu S; Yu H
J Appl Toxicol; 2015 Aug; 35(8):909-17. PubMed ID: 25512232
[TBL] [Abstract][Full Text] [Related]
9. Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury.
Bell CC; Lauschke VM; Vorrink SU; Palmgren H; Duffin R; Andersson TB; Ingelman-Sundberg M
Drug Metab Dispos; 2017 Apr; 45(4):419-429. PubMed ID: 28137721
[TBL] [Abstract][Full Text] [Related]
10. Evaluation of a Three-Dimensional Primary Human Hepatocyte Spheroid Model: Adoption and Industrialization for the Enhanced Detection of Drug-Induced Liver Injury.
Schofield CA; Walker TM; Taylor MA; Patel M; Vlachou DF; Macina JM; Vidgeon-Hart MP; Williams A; McGill PJ; Newman CF; Sakatis MZ
Chem Res Toxicol; 2021 Dec; 34(12):2485-2499. PubMed ID: 34797640
[TBL] [Abstract][Full Text] [Related]
11. Prediction of Drug-Induced Liver Injury in Micropatterned Co-cultures Containing iPSC-Derived Human Hepatocytes.
Ware BR; Berger DR; Khetani SR
Toxicol Sci; 2015 Jun; 145(2):252-62. PubMed ID: 25716675
[TBL] [Abstract][Full Text] [Related]
12. A novel evaluation method for determining drug-induced hepatotoxicity using 3D bio-printed human liver tissue.
Ide I; Nagao E; Kajiyama S; Mizoguchi N
Toxicol Mech Methods; 2020 Mar; 30(3):189-196. PubMed ID: 31736396
[TBL] [Abstract][Full Text] [Related]
13. Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid.
Foster AJ; Chouhan B; Regan SL; Rollison H; Amberntsson S; Andersson LC; Srivastava A; Darnell M; Cairns J; Lazic SE; Jang KJ; Petropolis DB; Kodella K; Rubins JE; Williams D; Hamilton GA; Ewart L; Morgan P
Arch Toxicol; 2019 Apr; 93(4):1021-1037. PubMed ID: 30915487
[TBL] [Abstract][Full Text] [Related]
14. Generation of hepatic spheroids using human hepatocyte-derived liver progenitor-like cells for hepatotoxicity screening.
Wang Z; Li W; Jing H; Ding M; Fu G; Yuan T; Huang W; Dai M; Tang D; Zeng M; Chen Y; Zhang H; Zhu X; Peng Y; Li Q; Yu WF; Yan HX; Zhai B
Theranostics; 2019; 9(22):6690-6705. PubMed ID: 31588244
[No Abstract] [Full Text] [Related]
15. Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing.
Tolosa L; Gómez-Lechón MJ; López S; Guzmán C; Castell JV; Donato MT; Jover R
Toxicol Sci; 2016 Jul; 152(1):214-29. PubMed ID: 27208088
[TBL] [Abstract][Full Text] [Related]
16. Bile canaliculi formation and biliary transport in 3D sandwich-cultured hepatocytes in dependence of the extracellular matrix composition.
Deharde D; Schneider C; Hiller T; Fischer N; Kegel V; Lübberstedt M; Freyer N; Hengstler JG; Andersson TB; Seehofer D; Pratschke J; Zeilinger K; Damm G
Arch Toxicol; 2016 Oct; 90(10):2497-511. PubMed ID: 27325308
[TBL] [Abstract][Full Text] [Related]
17. A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction.
Sun B; Liang Z; Wang Y; Yu Y; Zhou X; Geng X; Li B
Toxicology; 2024 Jun; 505():153829. PubMed ID: 38740170
[TBL] [Abstract][Full Text] [Related]
18. Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins.
Gerets HH; Tilmant K; Gerin B; Chanteux H; Depelchin BO; Dhalluin S; Atienzar FA
Cell Biol Toxicol; 2012 Apr; 28(2):69-87. PubMed ID: 22258563
[TBL] [Abstract][Full Text] [Related]
19. High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability.
Hiemstra S; Ramaiahgari SC; Wink S; Callegaro G; Coonen M; Meerman J; Jennen D; van den Nieuwendijk K; Dankers A; Snoeys J; de Bont H; Price L; van de Water B
Arch Toxicol; 2019 Oct; 93(10):2895-2911. PubMed ID: 31552476
[TBL] [Abstract][Full Text] [Related]
20. Proteomic responses of HepG2 cell monolayers and 3D spheroids to selected hepatotoxins.
Hurrell T; Lilley KS; Cromarty AD
Toxicol Lett; 2019 Jan; 300():40-50. PubMed ID: 30381255
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
