BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 29329650)

  • 1. Synthesis and anti-hepatocellular carcinoma activity of novel O
    Zou Y; Yan C; Liu JC; Huang ZJ; Xu JY; Zhou JP; Zhang HB; Zhang YH
    Chin J Nat Med; 2017 Dec; 15(12):928-937. PubMed ID: 29329650
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hybrid molecule from O2-(2,4-dinitrophenyl)diazeniumdiolate and oleanolic acid: a glutathione S-transferase π-activated nitric oxide prodrug with selective anti-human hepatocellular carcinoma activity and improved stability.
    Fu J; Liu L; Huang Z; Lai Y; Ji H; Peng S; Tian J; Zhang Y
    J Med Chem; 2013 Jun; 56(11):4641-55. PubMed ID: 23617697
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glycosylated diazeniumdiolate-based oleanolic acid derivatives: synthesis, in vitro and in vivo biological evaluation as anti-human hepatocellular carcinoma agents.
    Huang Z; Fu J; Liu L; Sun Y; Lai Y; Ji H; Knaus EE; Tian J; Zhang Y
    Org Biomol Chem; 2012 May; 10(19):3882-91. PubMed ID: 22473516
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and anti-human hepatocellular carcinoma activity of new nitric oxide-releasing glycosyl derivatives of oleanolic acid.
    Huang Z; Zhang Y; Zhao L; Jing Y; Lai Y; Zhang L; Guo Q; Yuan S; Zhang J; Chen L; Peng S; Tian J
    Org Biomol Chem; 2010 Feb; 8(3):632-9. PubMed ID: 20090981
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oleanolic acid-NO donor-platinum(II) trihybrid molecules: Targeting cytotoxicity on hepatoma cells with combined action mode and good safety.
    Fang L; Feng M; Chen F; Liu X; Shen H; Zhao J; Gou S
    Bioorg Med Chem; 2016 Oct; 24(19):4611-4619. PubMed ID: 27501909
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NG, a novel PABA/NO-based oleanolic acid derivative, induces human hepatoma cell apoptosis via a ROS/MAPK-dependent mitochondrial pathway.
    Liu L; Fu J; Li T; Cui R; Ling J; Yu X; Ji H; Zhang Y
    Eur J Pharmacol; 2012 Sep; 691(1-3):61-8. PubMed ID: 22824464
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis, and antihepatocellular carcinoma activity of nitric oxide releasing derivatives of oleanolic acid.
    Chen L; Zhang Y; Kong X; Lan E; Huang Z; Peng S; Kaufman DL; Tian J
    J Med Chem; 2008 Aug; 51(15):4834-8. PubMed ID: 18598019
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of nitric oxide-releasing derivatives of oleanolic acid as inhibitors of HepG2 cell apoptosis.
    Chen L; Zhang Y; Kong X; Peng S; Tian J
    Bioorg Med Chem Lett; 2007 Jun; 17(11):2979-82. PubMed ID: 17446070
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and synthesis of pyrazolo[3,4-d]pyrimidines: Nitric oxide releasing compounds targeting hepatocellular carcinoma.
    Elshaier YAMM; Shaaban MA; Abd El Hamid MK; Abdelrahman MH; Abou-Salim MA; Elgazwi SM; Halaweish F
    Bioorg Med Chem; 2017 Jun; 25(12):2956-2970. PubMed ID: 28487127
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and biological study of hybrid drug candidates of nitric oxide releasing cucurbitacin-inspired estrone analogs for treatment of hepatocellular carcinoma.
    Abou-Salim MA; Shaaban MA; Abd El Hameid MK; Elshaier YAMM; Halaweish F
    Bioorg Chem; 2019 Apr; 85():515-533. PubMed ID: 30807895
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel nitric oxide-releasing derivatives of farnesylthiosalicylic acid: synthesis and evaluation of antihepatocellular carcinoma activity.
    Ling Y; Ye X; Zhang Z; Zhang Y; Lai Y; Ji H; Peng S; Tian J
    J Med Chem; 2011 May; 54(9):3251-9. PubMed ID: 21504204
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, Characterization and Anti-hepatoma Activity of New Hederagenin Derivatives.
    Liu X; Sun L; Liu QH; Chen BQ; Liu YM
    Mini Rev Med Chem; 2020; 20(3):252-257. PubMed ID: 32134368
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Synthesis and anti-tumor activity of oleanolic acid derivatives].
    Meng YQ; Nie HH; Wang XC; Li D; Ge CX; Zhao N; Chen H; Cao B
    Yao Xue Xue Bao; 2011 Oct; 46(10):1215-20. PubMed ID: 22242453
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of a controlled-release drug delivery system made of oleanolic acid formulated into multivesicular liposomes on hepatocellular carcinoma in vitro and in vivo.
    Luo Y; Liu Z; Zhang X; Huang J; Yu X; Li J; Xiong D; Sun X; Zhong Z
    Int J Nanomedicine; 2016; 11():3111-29. PubMed ID: 27471381
    [TBL] [Abstract][Full Text] [Related]  

  • 15. JS-K, a nitric oxide prodrug, induces DNA damage and apoptosis in HBV-positive hepatocellular carcinoma HepG2.2.15 cell.
    Liu Z; Li G; Gou Y; Xiao D; Luo G; Saavedra JE; Liu J; Wang H
    Biomed Pharmacother; 2017 Aug; 92():989-997. PubMed ID: 28605880
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Combination of amino acid/dipeptide with nitric oxide donating oleanolic acid derivatives as PepT1 targeting antitumor prodrugs.
    Fang L; Wang M; Gou S; Liu X; Zhang H; Cao F
    J Med Chem; 2014 Feb; 57(3):1116-20. PubMed ID: 24422538
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Synthesis and biological evaluation of nitrate-oleanolic acid hybrids as inhibitors of HepG2 cell apoptosis].
    Chen L; Shang J; Wang ZF; Zhang YH; Tian JD
    Yao Xue Xue Bao; 2010 Dec; 45(12):1516-22. PubMed ID: 21351491
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis.
    Wang X; Bai H; Zhang X; Liu J; Cao P; Liao N; Zhang W; Wang Z; Hai C
    Carcinogenesis; 2013 Jun; 34(6):1323-30. PubMed ID: 23404993
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of phenyl substituted polyoxygenated xanthone derivatives as anti-hepatoma agents.
    Dai M; Yuan X; Kang J; Zhu ZJ; Yue RC; Yuan H; Chen BY; Zhang WD; Liu RH; Sun QY
    Eur J Med Chem; 2013 Nov; 69():159-66. PubMed ID: 24013415
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and synthesis of new hybrids from 2-cyano-3,12-dioxooleana- 9-dien-28-oic acid and O
    Kang F; Ai Y; Zhang Y; Huang Z
    Eur J Med Chem; 2018 Apr; 149():269-280. PubMed ID: 29501947
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.