BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 29331071)

  • 1. Hepatic PPARα function is controlled by polyubiquitination and proteasome-mediated degradation through the coordinated actions of PAQR3 and HUWE1.
    Zhao Z; Xu D; Wang Z; Wang L; Han R; Wang Z; Liao L; Chen Y
    Hepatology; 2018 Jul; 68(1):289-303. PubMed ID: 29331071
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PAQR9 regulates hepatic ketogenesis and fatty acid oxidation during fasting by modulating protein stability of PPARα.
    Lin Y; Chen L; You X; Li Z; Li C; Chen Y
    Mol Metab; 2021 Nov; 53():101331. PubMed ID: 34474167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of hepatic circadian metabolism by the E3 ubiquitin ligase HRD1-controlled CREBH/PPARα transcriptional program.
    Kim H; Wei J; Song Z; Mottillo E; Samavati L; Zhang R; Li L; Chen X; Jena BP; Lin JD; Fang D; Zhang K
    Mol Metab; 2021 Jul; 49():101192. PubMed ID: 33592335
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ATG101 Degradation by HUWE1-Mediated Ubiquitination Impairs Autophagy and Reduces Survival in Cancer Cells.
    Lee J; Kim J; Shin J; Kang Y; Choi J; Cheong H
    Int J Mol Sci; 2021 Aug; 22(17):. PubMed ID: 34502089
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ubiquitin Ligase COP1 Controls Hepatic Fat Metabolism by Targeting ATGL for Degradation.
    Ghosh M; Niyogi S; Bhattacharyya M; Adak M; Nayak DK; Chakrabarti S; Chakrabarti P
    Diabetes; 2016 Dec; 65(12):3561-3572. PubMed ID: 27658392
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DDB2 is involved in ubiquitination and degradation of PAQR3 and regulates tumorigenesis of gastric cancer cells.
    Qiao S; Guo W; Liao L; Wang L; Wang Z; Zhang R; Xu D; Zhang Y; Pan Y; Wang Z; Chen Y
    Biochem J; 2015 Aug; 469(3):469-80. PubMed ID: 26205499
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antiepileptic Drug-Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator-Activated Receptor
    Shizu R; Otsuka Y; Ezaki K; Ishii C; Arakawa S; Amaike Y; Abe T; Hosaka T; Sasaki T; Kanno Y; Miyata M; Yamazoe Y; Yoshinari K
    Mol Pharmacol; 2020 Nov; 98(5):634-647. PubMed ID: 32892155
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PPAR-alpha dependent regulation of vanin-1 mediates hepatic lipid metabolism.
    van Diepen JA; Jansen PA; Ballak DB; Hijmans A; Hooiveld GJ; Rommelaere S; Galland F; Naquet P; Rutjes FP; Mensink RP; Schrauwen P; Tack CJ; Netea MG; Kersten S; Schalkwijk J; Stienstra R
    J Hepatol; 2014 Aug; 61(2):366-72. PubMed ID: 24751833
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CRL4B
    Liu F; Cao L; Zhang T; Chang F; Xu Y; Li Q; Deng J; Li L; Shao G
    Biochem Biophys Res Commun; 2018 Jun; 501(2):440-447. PubMed ID: 29738775
    [TBL] [Abstract][Full Text] [Related]  

  • 10. mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux.
    Wan W; You Z; Zhou L; Xu Y; Peng C; Zhou T; Yi C; Shi Y; Liu W
    Mol Cell; 2018 Oct; 72(2):303-315.e6. PubMed ID: 30340022
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus.
    Xu D; Wang Z; Zhang Y; Jiang W; Pan Y; Song BL; Chen Y
    Nat Commun; 2015 Aug; 6():8100. PubMed ID: 26311497
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HUWE1 interacts with BRCA1 and promotes its degradation in the ubiquitin-proteasome pathway.
    Wang X; Lu G; Li L; Yi J; Yan K; Wang Y; Zhu B; Kuang J; Lin M; Zhang S; Shao G
    Biochem Biophys Res Commun; 2014 Feb; 444(4):549-54. PubMed ID: 24472556
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD.
    Montagner A; Polizzi A; Fouché E; Ducheix S; Lippi Y; Lasserre F; Barquissau V; Régnier M; Lukowicz C; Benhamed F; Iroz A; Bertrand-Michel J; Al Saati T; Cano P; Mselli-Lakhal L; Mithieux G; Rajas F; Lagarrigue S; Pineau T; Loiseau N; Postic C; Langin D; Wahli W; Guillou H
    Gut; 2016 Jul; 65(7):1202-14. PubMed ID: 26838599
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hepatic IRE1α regulates fasting-induced metabolic adaptive programs through the XBP1s-PPARα axis signalling.
    Shao M; Shan B; Liu Y; Deng Y; Yan C; Wu Y; Mao T; Qiu Y; Zhou Y; Jiang S; Jia W; Li J; Li J; Rui L; Yang L; Liu Y
    Nat Commun; 2014 Mar; 5():3528. PubMed ID: 24670948
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.
    Cheng YF; Tong M; Edge AS
    J Biol Chem; 2016 Sep; 291(40):21096-21109. PubMed ID: 27542412
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ubiquitin ligase E3 HUWE1/MULE targets transferrin receptor for degradation and suppresses ferroptosis in acute liver injury.
    Wu Y; Jiao H; Yue Y; He K; Jin Y; Zhang J; Zhang J; Wei Y; Luo H; Hao Z; Zhao X; Xia Q; Zhong Q; Zhang J
    Cell Death Differ; 2022 Sep; 29(9):1705-1718. PubMed ID: 35260822
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PPARalpha activation increases triglyceride mass and adipose differentiation-related protein in hepatocytes.
    Edvardsson U; Ljungberg A; Lindén D; William-Olsson L; Peilot-Sjögren H; Ahnmark A; Oscarsson J
    J Lipid Res; 2006 Feb; 47(2):329-40. PubMed ID: 16282640
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ubiquitin ligase MuRF1 regulates PPARα activity in the heart by enhancing nuclear export via monoubiquitination.
    Rodríguez JE; Liao JY; He J; Schisler JC; Newgard CB; Drujan D; Glass DJ; Frederick CB; Yoder BC; Lalush DS; Patterson C; Willis MS
    Mol Cell Endocrinol; 2015 Sep; 413():36-48. PubMed ID: 26116825
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PPARα induces cell apoptosis by destructing Bcl2.
    Gao J; Liu Q; Xu Y; Gong X; Zhang R; Zhou C; Su Z; Jin J; Shi H; Shi J; Hou Y
    Oncotarget; 2015 Dec; 6(42):44635-42. PubMed ID: 26556865
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhanced Hepatic PPARα Activity Links GLUT8 Deficiency to Augmented Peripheral Fasting Responses in Male Mice.
    Mayer AL; Zhang Y; Feng EH; Higgins CB; Adenekan O; Pietka TA; Beatty WL; DeBosch BJ
    Endocrinology; 2018 May; 159(5):2110-2126. PubMed ID: 29596655
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.