246 related articles for article (PubMed ID: 29333458)
1. SOX6 Downregulation Induces
Li J; Lai Y; Luo J; Luo L; Liu R; Liu Z; Zhao W
Biomed Res Int; 2017; 2017():9496058. PubMed ID: 29333458
[TBL] [Abstract][Full Text] [Related]
2. BCL11A Down-Regulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells.
Li J; Lai Y; Shi L
Hemoglobin; 2018 Jul; 42(4):225-230. PubMed ID: 30821197
[TBL] [Abstract][Full Text] [Related]
3. Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.
Fornari TA; Lanaro C; Albuquerque DM; Ferreira R; Costa FF
Exp Biol Med (Maywood); 2017 Feb; 242(3):267-274. PubMed ID: 27591578
[TBL] [Abstract][Full Text] [Related]
4. Acyclovir induces fetal hemoglobin via downregulation of γ-globin repressors, BCL11A and SOX6 trans-acting factors.
Ali H; Khan F; Ghulam Musharraf S
Biochem Pharmacol; 2021 Aug; 190():114612. PubMed ID: 34010599
[TBL] [Abstract][Full Text] [Related]
5. Inducing indel mutation in the SOX6 gene by zinc finger nuclease for gamma reactivation: An approach towards gene therapy of beta thalassemia.
Modares Sadeghi M; Shariati L; Hejazi Z; Shahbazi M; Tabatabaiefar MA; Khanahmad H
J Cell Biochem; 2018 Mar; 119(3):2512-2519. PubMed ID: 28941328
[TBL] [Abstract][Full Text] [Related]
6. Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia.
Bao X; Zhang X; Wang L; Wang Z; Huang J; Zhang Q; Ye Y; Liu Y; Chen D; Zuo Y; Liu Q; Xu P; Huang B; Fang J; Lao J; Feng X; Li Y; Kurita R; Nakamura Y; Yu W; Ju C; Huang C; Mohandas N; Li D; Zhao C; Xu X
Am J Hum Genet; 2021 Apr; 108(4):709-721. PubMed ID: 33735615
[TBL] [Abstract][Full Text] [Related]
7. Disruption of SOX6 gene using CRISPR/Cas9 technology for gamma-globin reactivation: An approach towards gene therapy of β-thalassemia.
Shariati L; Rohani F; Heidari Hafshejani N; Kouhpayeh S; Boshtam M; Mirian M; Rahimmanesh I; Hejazi Z; Modarres M; Pieper IL; Khanahmad H
J Cell Biochem; 2018 Nov; 119(11):9357-9363. PubMed ID: 30010219
[TBL] [Abstract][Full Text] [Related]
8. Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients.
Fibach E; Prus E; Bianchi N; Zuccato C; Breveglieri G; Salvatori F; Finotti A; Lipucci di Paola M; Brognara E; Lampronti I; Borgatti M; Gambari R
Int J Mol Med; 2012 Jun; 29(6):974-82. PubMed ID: 22378234
[TBL] [Abstract][Full Text] [Related]
9. Monoterpenes as therapeutic candidates to induce fetal hemoglobin synthesis and up-regulation of gamma-globin gene: An in vitro and in vivo investigation.
Iftikhar F; Khan MBN; Musharraf SG
Eur J Pharmacol; 2021 Jan; 891():173700. PubMed ID: 33137331
[TBL] [Abstract][Full Text] [Related]
10. A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts.
Wilber A; Tschulena U; Hargrove PW; Kim YS; Persons DA; Barbas CF; Nienhuis AW
Blood; 2010 Apr; 115(15):3033-41. PubMed ID: 20190190
[TBL] [Abstract][Full Text] [Related]
11. Plastrum testudinis induces γ-globin gene expression through epigenetic histone modifications within the γ-globin gene promoter via activation of the p38 MAPK signaling pathway.
Qian X; Chen J; Zhao D; Guo L; Qian X
Int J Mol Med; 2013 Jun; 31(6):1418-28. PubMed ID: 23588991
[TBL] [Abstract][Full Text] [Related]
12. Quantification of HBG mRNA in primary erythroid cultures: prediction of the response to hydroxyurea in sickle cell and beta-thalassemia.
Pecoraro A; Rigano P; Troia A; Calzolari R; Scazzone C; Maggio A; Steinberg MH; Di Marzo R
Eur J Haematol; 2014 Jan; 92(1):66-72. PubMed ID: 24112139
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping.
Krivega I; Byrnes C; de Vasconcellos JF; Lee YT; Kaushal M; Dean A; Miller JL
Blood; 2015 Jul; 126(5):665-72. PubMed ID: 25979948
[TBL] [Abstract][Full Text] [Related]
14. Tenofovir disoproxil fumarate induces fetal hemoglobin production in K562 cells and β-YAC transgenic mice: A therapeutic approach for γ-globin induction.
Khan F; Ali H; Musharraf SG
Exp Cell Res; 2020 Sep; 394(2):112168. PubMed ID: 32653411
[TBL] [Abstract][Full Text] [Related]
15. Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.
Wilber A; Hargrove PW; Kim YS; Riberdy JM; Sankaran VG; Papanikolaou E; Georgomanoli M; Anagnou NP; Orkin SH; Nienhuis AW; Persons DA
Blood; 2011 Mar; 117(10):2817-26. PubMed ID: 21156846
[TBL] [Abstract][Full Text] [Related]
16. BCL11A-targeted γ-globin gene induction by triterpenoid glycosides of Fagonia indica: A preclinical scientific validation of indigenous herb for the treatment of β-hemoglobinopathies.
Iftikhar F; Khan MBN; Tehreem S; Kanwal N; Musharraf SG
Bioorg Chem; 2023 Nov; 140():106768. PubMed ID: 37586133
[TBL] [Abstract][Full Text] [Related]
17. Cilostazol-mediated reversion of γ-globin silencing is associated with a high level of HbF production: A potential therapeutic candidate for β-globin disorders.
Ali H; Khan F; Musharraf SG
Biomed Pharmacother; 2021 Oct; 142():112058. PubMed ID: 34426256
[TBL] [Abstract][Full Text] [Related]
18. Pomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors.
Dulmovits BM; Appiah-Kubi AO; Papoin J; Hale J; He M; Al-Abed Y; Didier S; Gould M; Husain-Krautter S; Singh SA; Chan KW; Vlachos A; Allen SL; Taylor N; Marambaud P; An X; Gallagher PG; Mohandas N; Lipton JM; Liu JM; Blanc L
Blood; 2016 Mar; 127(11):1481-92. PubMed ID: 26679864
[TBL] [Abstract][Full Text] [Related]
19. Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells.
Chou YC; Chen RL; Lai ZS; Song JS; Chao YS; Shen CK
Mol Cell Biol; 2015 Jul; 35(14):2541-53. PubMed ID: 25986606
[TBL] [Abstract][Full Text] [Related]
20. When basic science reaches into rational therapeutic design: from historical to novel leads for the treatment of β-globinopathies.
Andrieu-Soler C; Soler E
Curr Opin Hematol; 2020 May; 27(3):141-148. PubMed ID: 32167946
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]