BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

287 related articles for article (PubMed ID: 29335202)

  • 1. 5-Bromo-oxoisoaporphine platinum(II) complexes exhibit tumor cell cytotoxcicity via inhibition of telomerase activity and disruption of c-myc G-quadruplex DNA and mitochondrial functions.
    Wei ZZ; Qin QP; Meng T; Deng CX; Liang H; Chen ZF
    Eur J Med Chem; 2018 Feb; 145():360-369. PubMed ID: 29335202
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stabilization of c-myc G-Quadruplex DNA, inhibition of telomerase activity, disruption of mitochondrial functions and tumor cell apoptosis by platinum(II) complex with 9-amino-oxoisoaporphine.
    Qin JL; Qin QP; Wei ZZ; Yu YC; Meng T; Wu CX; Liang YL; Liang H; Chen ZF
    Eur J Med Chem; 2016 Nov; 124():417-427. PubMed ID: 27597417
    [TBL] [Abstract][Full Text] [Related]  

  • 3. High in vivo antitumor activity of cobalt oxoisoaporphine complexes by targeting G-quadruplex DNA, telomerase and disrupting mitochondrial functions.
    Qin QP; Qin JL; Meng T; Lin WH; Zhang CH; Wei ZZ; Chen JN; Liu YC; Liang H; Chen ZF
    Eur J Med Chem; 2016 Nov; 124():380-392. PubMed ID: 27597414
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stabilization of G-quadruplex DNA, inhibition of telomerase activity, and tumor cell apoptosis by organoplatinum(II) complexes with oxoisoaporphine.
    Chen ZF; Qin QP; Qin JL; Liu YC; Huang KB; Li YL; Meng T; Zhang GH; Peng Y; Luo XJ; Liang H
    J Med Chem; 2015 Mar; 58(5):2159-79. PubMed ID: 25650792
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Preparation of 4-([2,2':6',2″-terpyridin]-4'-yl)-N,N-diethylaniline Ni(II) and Pt(II) complexes and exploration of their in vitro cytotoxic activities.
    Zou HH; Wang L; Long ZX; Qin QP; Song ZK; Xie T; Zhang SH; Liu YC; Lin B; Chen ZF
    Eur J Med Chem; 2016 Jan; 108():1-12. PubMed ID: 26619388
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel tacrine platinum(II) complexes display high anticancer activity via inhibition of telomerase activity, dysfunction of mitochondria, and activation of the p53 signaling pathway.
    Qin QP; Wang SL; Tan MX; Wang ZF; Luo DM; Zou BQ; Liu YC; Yao PF; Liang H
    Eur J Med Chem; 2018 Oct; 158():106-122. PubMed ID: 30205260
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, crystal structure and biological evaluation of a new dasatinib copper(II) complex as telomerase inhibitor.
    Qin QP; Meng T; Tan MX; Liu YC; Luo XJ; Zou BQ; Liang H
    Eur J Med Chem; 2018 Jan; 143():1597-1603. PubMed ID: 29133054
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of a platinum(II) complex with 2-(4-methoxy-phenyl) imidazo [4,5-f]-[1,10] phenanthrolin and study of its antitumor activity.
    Qin QP; Chen ZF; Shen WY; Jiang YH; Cao D; Li YL; Xu QM; Liu YC; Huang KB; Liang H
    Eur J Med Chem; 2015 Jan; 89():77-87. PubMed ID: 25462228
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of two platinum(II) complexes with 2-methyl-8-quinolinol derivatives as ligands and study of their antitumor activities.
    Qin QP; Wang SL; Tan MX; Liu YC; Meng T; Zou BQ; Liang H
    Eur J Med Chem; 2019 Jan; 161():334-342. PubMed ID: 30384040
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and antitumor mechanisms of two novel platinum(ii) complexes with 3-(2'-benzimidazolyl)-7-methoxycoumarin.
    Qin QP; Wang SL; Tan MX; Wang ZF; Huang XL; Wei QM; Shi BB; Zou BQ; Liang H
    Metallomics; 2018 Aug; 10(8):1160-1169. PubMed ID: 30083683
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Studies on antitumor mechanism of two planar platinum(II) complexes with 8-hydroxyquinoline: synthesis, characterization, cytotoxicity, cell cycle and apoptosis.
    Qin QP; Chen ZF; Qin JL; He XJ; Li YL; Liu YC; Huang KB; Liang H
    Eur J Med Chem; 2015 Mar; 92():302-13. PubMed ID: 25575314
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stabilization of human telomeric G-quadruplex and inhibition of telomerase activity by propeller-shaped trinuclear Pt(II) complexes.
    Xu CX; Shen Y; Hu Q; Zheng YX; Cao Q; Qin PZ; Zhao Y; Ji LN; Mao ZW
    Chem Asian J; 2014 Sep; 9(9):2519-26. PubMed ID: 24996049
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A platinum(II) complex of liriodenine from traditional Chinese medicine (TCM): Cell cycle arrest, cell apoptosis induction and telomerase inhibition activity via G-quadruplex DNA stabilization.
    Li YL; Qin QP; Liu YC; Chen ZF; Liang H
    J Inorg Biochem; 2014 Aug; 137():12-21. PubMed ID: 24798373
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of substituted 3-(2'-benzimidazolyl)coumarin platinum(II) complexes as new telomerase inhibitors.
    Meng T; Qin QP; Wang ZR; Peng LT; Zou HH; Gan ZY; Tan MX; Wang K; Liang FP
    J Inorg Biochem; 2018 Dec; 189():143-150. PubMed ID: 30265997
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-based design of platinum(II) complexes as c-myc oncogene down-regulators and luminescent probes for G-quadruplex DNA.
    Wang P; Leung CH; Ma DL; Yan SC; Che CM
    Chemistry; 2010 Jun; 16(23):6900-11. PubMed ID: 20437426
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Homo- and heteroleptic Pt(II) complexes of ONN donor hydrazone and 4-picoline: A synthetic, structural and detailed mechanistic anticancer investigation.
    Rahman FU; Bhatti MZ; Ali A; Duong HQ; Zhang Y; Yang B; Koppireddi S; Lin Y; Wang H; Li ZT; Zhang DW
    Eur J Med Chem; 2018 Jan; 143():1039-1052. PubMed ID: 29232581
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Water-Soluble Ruthenium(II) Complexes with Chiral 4-(2,3-Dihydroxypropyl)-formamide Oxoaporphine (FOA): In Vitro and in Vivo Anticancer Activity by Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Induction of Tumor Cell Apoptosis.
    Chen ZF; Qin QP; Qin JL; Zhou J; Li YL; Li N; Liu YC; Liang H
    J Med Chem; 2015 Jun; 58(11):4771-89. PubMed ID: 25988535
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and in vitro antitumor activity evaluation of copper(II) complexes with 5-pyridin-2-yl-[1,3]dioxolo[4,5-g]isoquinoline derivatives.
    Zhang YL; Deng CX; Zhou WF; Zhou LY; Cao QQ; Shen WY; Liang H; Chen ZF
    J Inorg Biochem; 2019 Dec; 201():110820. PubMed ID: 31518871
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Morpholine or methylpiperazine and salicylaldimine based heteroleptic square planner platinum (II) complexes: In vitro anticancer study and growth retardation effect on E. coli.
    Rahman FU; Ali A; Khan IU; Duong HQ; Yu SB; Lin YJ; Wang H; Li ZT; Zhang DW
    Eur J Med Chem; 2017 May; 131():263-274. PubMed ID: 28334655
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Strong in vitro and vivo cytotoxicity of novel organoplatinum(II) complexes with quinoline-coumarin derivatives.
    Qin QP; Wang ZF; Huang XL; Tan MX; Zou BQ; Liang H
    Eur J Med Chem; 2019 Dec; 184():111751. PubMed ID: 31593828
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.