BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

270 related articles for article (PubMed ID: 29342136)

  • 1. Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia.
    Tzoneva G; Dieck CL; Oshima K; Ambesi-Impiombato A; Sánchez-Martín M; Madubata CJ; Khiabanian H; Yu J; Waanders E; Iacobucci I; Sulis ML; Kato M; Koh K; Paganin M; Basso G; Gastier-Foster JM; Loh ML; Kirschner-Schwabe R; Mullighan CG; Rabadan R; Ferrando AA
    Nature; 2018 Jan; 553(7689):511-514. PubMed ID: 29342136
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.
    Dieck CL; Tzoneva G; Forouhar F; Carpenter Z; Ambesi-Impiombato A; Sánchez-Martín M; Kirschner-Schwabe R; Lew S; Seetharaman J; Tong L; Ferrando AA
    Cancer Cell; 2018 Jul; 34(1):136-147.e6. PubMed ID: 29990496
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.
    Tzoneva G; Perez-Garcia A; Carpenter Z; Khiabanian H; Tosello V; Allegretta M; Paietta E; Racevskis J; Rowe JM; Tallman MS; Paganin M; Basso G; Hof J; Kirschner-Schwabe R; Palomero T; Rabadan R; Ferrando A
    Nat Med; 2013 Mar; 19(3):368-71. PubMed ID: 23377281
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetics and mechanisms of NT5C2-driven chemotherapy resistance in relapsed ALL.
    Dieck CL; Ferrando A
    Blood; 2019 May; 133(21):2263-2268. PubMed ID: 30910786
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of
    Moriyama T; Liu S; Li J; Meyer J; Zhao X; Yang W; Shao Y; Heath R; Hnízda A; Carroll WL; Yang JJ
    Mol Cancer Ther; 2019 Oct; 18(10):1887-1895. PubMed ID: 31358663
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CRISPR/Cas9-Mediated Induction of Relapse-Specific
    Nguyen TTT; Tanaka Y; Sanada M; Hosaka M; Tamai M; Kagami K; Komatsu C; Somazu S; Harama D; Kasai S; Watanabe A; Akahane K; Goi K; Inukai T
    Mol Pharmacol; 2023 Apr; 103(4):199-210. PubMed ID: 36669880
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmacologic Inhibition of NT5C2 Reverses Genetic and Nongenetic Drivers of 6-MP Resistance in Acute Lymphoblastic Leukemia.
    Reglero C; Dieck CL; Zask A; Forouhar F; Laurent AP; Lin WW; Albero R; Miller HI; Ma C; Gastier-Foster JM; Loh ML; Tong L; Stockwell BR; Palomero T; Ferrando AA
    Cancer Discov; 2022 Nov; 12(11):2646-2665. PubMed ID: 35984649
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NUDT15 polymorphism and NT5C2 and PRPS1 mutations influence thiopurine sensitivity in acute lymphoblastic leukaemia cells.
    Somazu S; Tanaka Y; Tamai M; Watanabe A; Kagami K; Abe M; Harama D; Shinohara T; Akahane K; Goi K; Sugita K; Moriyama T; Yang J; Goto H; Minegishi M; Iwamoto S; Takita J; Inukai T
    J Cell Mol Med; 2021 Nov; 25(22):10521-10533. PubMed ID: 34636169
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Subclonal NT5C2 mutations are associated with poor outcomes after relapse of pediatric acute lymphoblastic leukemia.
    Barz MJ; Hof J; Groeneveld-Krentz S; Loh JW; Szymansky A; Astrahantseff K; von Stackelberg A; Khiabanian H; Ferrando AA; Eckert C; Kirschner-Schwabe R
    Blood; 2020 Mar; 135(12):921-933. PubMed ID: 31971569
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia.
    Tulstrup M; Grosjean M; Nielsen SN; Grell K; Wolthers BO; Wegener PS; Jonsson OG; Lund B; Harila-Saari A; Abrahamsson J; Vaitkeviciene G; Pruunsild K; Toft N; Holm M; Hulegårdh E; Liestøl S; Griskevicius L; Punab M; Wang J; Carroll WL; Zhang Z; Dalgaard MD; Gupta R; Nersting J; Schmiegelow K
    Leukemia; 2018 Dec; 32(12):2527-2535. PubMed ID: 30201983
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia.
    Meyer JA; Wang J; Hogan LE; Yang JJ; Dandekar S; Patel JP; Tang Z; Zumbo P; Li S; Zavadil J; Levine RL; Cardozo T; Hunger SP; Raetz EA; Evans WE; Morrison DJ; Mason CE; Carroll WL
    Nat Genet; 2013 Mar; 45(3):290-4. PubMed ID: 23377183
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Screening for gene mutations: will identification of NT5C2 mutations help predict the chance of relapse in acute lymphoblastic leukemia?
    Meyer JA; Carroll WL; Bhatla T
    Expert Rev Hematol; 2013 Jun; 6(3):223-4. PubMed ID: 23782074
    [No Abstract]   [Full Text] [Related]  

  • 13. Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
    Hnízda A; Fábry M; Moriyama T; Pachl P; Kugler M; Brinsa V; Ascher DB; Carroll WL; Novák P; Žaliová M; Trka J; Řezáčová P; Yang JJ; Veverka V
    Leukemia; 2018 Jun; 32(6):1393-1403. PubMed ID: 29535428
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Resistance revealed in acute lymphoblastic leukemia.
    Aster JC; DeAngelo DJ
    Nat Med; 2013 Mar; 19(3):264-5. PubMed ID: 23467232
    [No Abstract]   [Full Text] [Related]  

  • 15. Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia.
    Hnízda A; Škerlová J; Fábry M; Pachl P; Šinalová M; Vrzal L; Man P; Novák P; Řezáčová P; Veverka V
    BMC Biol; 2016 Oct; 14(1):91. PubMed ID: 27756303
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia.
    Li B; Brady SW; Ma X; Shen S; Zhang Y; Li Y; Szlachta K; Dong L; Liu Y; Yang F; Wang N; Flasch DA; Myers MA; Mulder HL; Ding L; Liu Y; Tian L; Hagiwara K; Xu K; Zhou X; Sioson E; Wang T; Yang L; Zhao J; Zhang H; Shao Y; Sun H; Sun L; Cai J; Sun HY; Lin TN; Du L; Li H; Rusch M; Edmonson MN; Easton J; Zhu X; Zhang J; Cheng C; Raphael BJ; Tang J; Downing JR; Alexandrov LB; Zhou BS; Pui CH; Yang JJ; Zhang J
    Blood; 2020 Jan; 135(1):41-55. PubMed ID: 31697823
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia.
    Oshima K; Khiabanian H; da Silva-Almeida AC; Tzoneva G; Abate F; Ambesi-Impiombato A; Sanchez-Martin M; Carpenter Z; Penson A; Perez-Garcia A; Eckert C; Nicolas C; Balbin M; Sulis ML; Kato M; Koh K; Paganin M; Basso G; Gastier-Foster JM; Devidas M; Loh ML; Kirschner-Schwabe R; Palomero T; Rabadan R; Ferrando AA
    Proc Natl Acad Sci U S A; 2016 Oct; 113(40):11306-11311. PubMed ID: 27655895
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic drivers of vulnerability and resistance in relapsed acute lymphoblastic leukemia.
    Lu SX; Abdel-Wahab O
    Proc Natl Acad Sci U S A; 2016 Oct; 113(40):11071-11073. PubMed ID: 27663730
    [No Abstract]   [Full Text] [Related]  

  • 19. NT5C2 novel splicing variant expands the phenotypic spectrum of Spastic Paraplegia (SPG45): case report of a new member of thin corpus callosum SPG-Subgroup.
    Elsaid MF; Ibrahim K; Chalhoub N; Elsotouhy A; El Mudehki N; Abdel Aleem A
    BMC Med Genet; 2017 Mar; 18(1):33. PubMed ID: 28327087
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [NT5C2 expression in children with acute leukemia and its clinical significance].
    Wang Y; An X; Liu J; Zhang N; Liu Z; Liang S; Yu J
    Zhonghua Xue Ye Xue Za Zhi; 2015 Sep; 36(9):748-53. PubMed ID: 26462774
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.