These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 29345921)

  • 1. Molecular Mechanisms in the Selectivity of Nonsteroidal Anti-Inflammatory Drugs.
    Shamsudin Y; Gutiérrez-de-Terán H; Åqvist J
    Biochemistry; 2018 Feb; 57(7):1236-1248. PubMed ID: 29345921
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Probing the Time Dependency of Cyclooxygenase-1 Inhibitors by Computer Simulations.
    Shamsudin Y; Gutiérrez-de-Terán H; Åqvist J
    Biochemistry; 2017 Apr; 56(13):1911-1920. PubMed ID: 28304156
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Toward an optimal docking and free energy calculation scheme in ligand design with application to COX-1 inhibitors.
    Shamsudin Y; Gutiérrez-de-Terán H; Boukharta L; Åqvist J
    J Chem Inf Model; 2014 May; 54(5):1488-99. PubMed ID: 24786949
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deciphering the mechanism behind the varied binding activities of COXIBs through Molecular Dynamic Simulations, MM-PBSA binding energy calculations and per-residue energy decomposition studies.
    Chaudhary N; Aparoy P
    J Biomol Struct Dyn; 2017 Mar; 35(4):868-882. PubMed ID: 26982261
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coxibs interfere with the action of aspirin by binding tightly to one monomer of cyclooxygenase-1.
    Rimon G; Sidhu RS; Lauver DA; Lee JY; Sharma NP; Yuan C; Frieler RA; Trievel RC; Lucchesi BR; Smith WL
    Proc Natl Acad Sci U S A; 2010 Jan; 107(1):28-33. PubMed ID: 19955429
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Perspective assessment of COX-1 and COX-2 selectivity of nonsteroidal anti-inflammatory drugs from clinical practice: use of genetic function approximation.
    Zambre AP; Ganure AL; Shinde DB; Kulkarni VM
    J Chem Inf Model; 2007; 47(2):635-43. PubMed ID: 17256838
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Computer aided drug design approaches to develop cyclooxygenase based novel anti-inflammatory and anti-cancer drugs.
    Reddy RN; Mutyala R; Aparoy P; Reddanna P; Reddy MR
    Curr Pharm Des; 2007; 13(34):3505-17. PubMed ID: 18220787
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Origin of the Enigmatic Stepwise Tight-Binding Inhibition of Cyclooxygenase-1.
    Shamsudin Y; Kazemi M; Gutiérrez-de-Terán H; Åqvist J
    Biochemistry; 2015 Dec; 54(49):7283-91. PubMed ID: 26562384
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Docking Studies, Synthesis and Biological Evaluation of β-aryl-β-hydroxy Propanoic Acids for Anti-inflammatory Activity.
    Savic J; Dilber S; Milenkovic M; Kotur-Stevuljevic J; Markovic B; Vladimirov S; Brboric J
    Med Chem; 2017; 13(2):186-195. PubMed ID: 27605092
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study.
    Abdel-Aziz AA; ElTahir KE; Asiri YA
    Eur J Med Chem; 2011 May; 46(5):1648-55. PubMed ID: 21388719
    [TBL] [Abstract][Full Text] [Related]  

  • 11. COX Inhibition Profile and Molecular Docking Studies of Some 2-(Trimethoxyphenyl)-Thiazoles.
    Oniga SD; Pacureanu L; Stoica CI; Palage MD; Crăciun A; Rusu LR; Crisan EL; Araniciu C
    Molecules; 2017 Sep; 22(9):. PubMed ID: 28891941
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors.
    Kalgutkar AS; Marnett AB; Crews BC; Remmel RP; Marnett LJ
    J Med Chem; 2000 Jul; 43(15):2860-70. PubMed ID: 10956194
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4(3H)-quinazolinones.
    Abdel-Aziz AA; Abou-Zeid LA; ElTahir KEH; Ayyad RR; El-Sayed MA; El-Azab AS
    Eur J Med Chem; 2016 Oct; 121():410-421. PubMed ID: 27318118
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular basis of cyclooxygenase enzymes (COXs) selective inhibition.
    Limongelli V; Bonomi M; Marinelli L; Gervasio FL; Cavalli A; Novellino E; Parrinello M
    Proc Natl Acad Sci U S A; 2010 Mar; 107(12):5411-6. PubMed ID: 20215464
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 2-Substituted Benzoxazoles as Potent Anti-Inflammatory Agents: Synthesis, Molecular Docking and In vivo Anti-Ulcerogenic Studies.
    Hamid I; Nadeem H; Ansari SF; Khiljee S; Abbasi I; Bukhari A; Arif M; Imran M
    Med Chem; 2022; 18(7):791-809. PubMed ID: 34931968
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives.
    Moraes ADTO; Miranda MDS; Jacob ÍTT; Amorim CADC; Moura RO; Silva SÂSD; Soares MBP; Almeida SMV; Souza TRCL; Oliveira JF; Silva TGD; Melo CML; Moreira DRM; Lima MDCA
    Bioorg Med Chem; 2018 Nov; 26(20):5388-5396. PubMed ID: 30293795
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): cyclooxygenase (COX) inhibition and beyond.
    Rao P; Knaus EE
    J Pharm Pharm Sci; 2008 Sep; 11(2):81s-110s. PubMed ID: 19203472
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of cyclooxygenase by blocking the reducing cosubstrate at the peroxidase site: Discovery of galangin as a novel cyclooxygenase inhibitor.
    Bai HW; Yang C; Wang P; Rao S; Zhu BT
    Eur J Pharmacol; 2021 May; 899():174036. PubMed ID: 33737009
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In situ click chemistry generation of cyclooxygenase-2 inhibitors.
    Bhardwaj A; Kaur J; Wuest M; Wuest F
    Nat Commun; 2017 Feb; 8(1):1. PubMed ID: 28232747
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-based QSAR study on differential inhibition of human prostaglandin endoperoxide H synthase-2 (COX-2) by nonsteroidal anti-inflammatory drugs.
    Pouplana R; Lozano JJ; Pérez C; Ruiz J
    J Comput Aided Mol Des; 2002 Oct; 16(10):683-709. PubMed ID: 12650588
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.