BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 29346025)

  • 1. Linkage of Metabolic Defects to Activated PIK3CA Alleles in Endothelial Cells Derived from Lymphatic Malformation.
    Glaser K; Dickie P; Neilson D; Osborn A; Dickie BH
    Lymphat Res Biol; 2018 Feb; 16(1):43-55. PubMed ID: 29346025
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activating PIK3CA alleles and lymphangiogenic phenotype of lymphatic endothelial cells isolated from lymphatic malformations.
    Osborn AJ; Dickie P; Neilson DE; Glaser K; Lynch KA; Gupta A; Dickie BH
    Hum Mol Genet; 2015 Feb; 24(4):926-38. PubMed ID: 25292196
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel method for isolating lymphatic endothelial cells from lymphatic malformations and detecting PIK3CA somatic mutation in these isolated cells.
    Usui H; Tsurusaki Y; Shimbo H; Saitsu H; Harada N; Kitagawa N; Mochizuki K; Masuda M; Kurosawa K; Shinkai M
    Surg Today; 2021 Mar; 51(3):439-446. PubMed ID: 32876734
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PIK3CA mutations are specifically localized to lymphatic endothelial cells of lymphatic malformations.
    Blesinger H; Kaulfuß S; Aung T; Schwoch S; Prantl L; Rößler J; Wilting J; Becker J
    PLoS One; 2018; 13(7):e0200343. PubMed ID: 29985963
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PIK3CA mutation sensitizes breast cancer cells to synergistic therapy of PI3K inhibition and AMPK activation.
    Liu S; Tang Y; Yan M; Jiang W
    Invest New Drugs; 2018 Oct; 36(5):763-772. PubMed ID: 29504069
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AICAR induces cyclooxygenase-2 expression through AMP-activated protein kinase-transforming growth factor-beta-activated kinase 1-p38 mitogen-activated protein kinase signaling pathway.
    Chang MY; Ho FM; Wang JS; Kang HC; Chang Y; Ye ZX; Lin WW
    Biochem Pharmacol; 2010 Oct; 80(8):1210-20. PubMed ID: 20615388
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The YAP signaling pathway promotes the progression of lymphatic malformations through the activation of lymphatic endothelial cells.
    Zhong W; Jiang H; Zou Y; Ren J; Li Z; He K; Zhao J; Zhou X; Mou D; Cai Y
    Pediatr Res; 2021 Jan; 89(1):110-117. PubMed ID: 32279070
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation.
    Martinez-Corral I; Zhang Y; Petkova M; Ortsäter H; Sjöberg S; Castillo SD; Brouillard P; Libbrecht L; Saur D; Graupera M; Alitalo K; Boon L; Vikkula M; Mäkinen T
    Nat Commun; 2020 Jun; 11(1):2869. PubMed ID: 32513927
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Non-hotspot PIK3CA mutations are more frequent in CLOVES than in common or combined lymphatic malformations.
    Brouillard P; Schlögel MJ; Homayun Sepehr N; Helaers R; Queisser A; Fastré E; Boutry S; Schmitz S; Clapuyt P; Hammer F; Dompmartin A; Weitz-Tuoretmaa A; Laranne J; Pasquesoone L; Vilain C; Boon LM; Vikkula M
    Orphanet J Rare Dis; 2021 Jun; 16(1):267. PubMed ID: 34112235
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lymphatic and other vascular malformative/overgrowth disorders are caused by somatic mutations in PIK3CA.
    Luks VL; Kamitaki N; Vivero MP; Uller W; Rab R; Bovée JV; Rialon KL; Guevara CJ; Alomari AI; Greene AK; Fishman SJ; Kozakewich HP; Maclellan RA; Mulliken JB; Rahbar R; Spencer SA; Trenor CC; Upton J; Zurakowski D; Perkins JA; Kirsh A; Bennett JT; Dobyns WB; Kurek KC; Warman ML; McCarroll SA; Murillo R
    J Pediatr; 2015 Apr; 166(4):1048-54.e1-5. PubMed ID: 25681199
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A somatic mutation in PIK3CD unravels a novel candidate gene for lymphatic malformation.
    Wang S; Wang W; Zhang X; Gui J; Zhang J; Guo Y; Liu Y; Han L; Liu Q; Li Y; Sun N; Liu Z; Du J; Tai J; Ni X
    Orphanet J Rare Dis; 2021 May; 16(1):208. PubMed ID: 33964933
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genomic landscape of lymphatic malformations: a case series and response to the PI3Kα inhibitor alpelisib in an
    Shaheen MF; Tse JY; Sokol ES; Masterson M; Bansal P; Rabinowitz I; Tarleton CA; Dobroff AS; Smith TL; Bocklage TJ; Mannakee BK; Gutenkunst RN; Bischoff J; Ness SA; Riedlinger GM; Groisberg R; Pasqualini R; Ganesan S; Arap W
    Elife; 2022 Jul; 11():. PubMed ID: 35787784
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The anti-diabetic AMPK activator AICAR reduces IL-6 and IL-8 in human adipose tissue and skeletal muscle cells.
    Lihn AS; Pedersen SB; Lund S; Richelsen B
    Mol Cell Endocrinol; 2008 Sep; 292(1-2):36-41. PubMed ID: 18606210
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of the metabolic sensor-AMP activated protein kinase reverses impairment of angiogenesis in aging myocardial microvascular endothelial cells. Implications for the aging heart.
    Ahluwalia A; Tarnawski AS
    J Physiol Pharmacol; 2011 Oct; 62(5):583-7. PubMed ID: 22204807
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Constitutively active PIK3CA mutations are expressed by lymphatic and vascular endothelial cells in capillary lymphatic venous malformation.
    Le Cras TD; Goines J; Lakes N; Pastura P; Hammill AM; Adams DM; Boscolo E
    Angiogenesis; 2020 Aug; 23(3):425-442. PubMed ID: 32350708
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells.
    Hattori Y; Suzuki K; Hattori S; Kasai K
    Hypertension; 2006 Jun; 47(6):1183-8. PubMed ID: 16636195
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of HDAC-Mediated Repression and Gain of NF-κB Activation Underlie Cytokine Induction in ARID1A- and PIK3CA-Mutation-Driven Ovarian Cancer.
    Kim M; Lu F; Zhang Y
    Cell Rep; 2016 Sep; 17(1):275-288. PubMed ID: 27681437
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Implication of S-adenosylhomocysteine hydrolase in inhibition of TNF-alpha- and IL-1beta-induced expression of inflammatory mediators by AICAR in RPE cells.
    Qin S; Ni M; De Vries GW
    Invest Ophthalmol Vis Sci; 2008 Mar; 49(3):1274-81. PubMed ID: 18326758
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytoprotective effect of β-lapachone by inducing heme oxygenase-1 expression and AMP-activated protein kinase activation in human endothelial cells.
    Byun SJ; Son Y; Pae HO
    Eur Rev Med Pharmacol Sci; 2014; 18(7):949-58. PubMed ID: 24763872
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase.
    Kuo CL; Ho FM; Chang MY; Prakash E; Lin WW
    J Cell Biochem; 2008 Feb; 103(3):931-40. PubMed ID: 17615555
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.