These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 29352227)

  • 1. LY2087101 and dFBr share transmembrane binding sites in the (α4)3(β2)2 Nicotinic Acetylcholine Receptor.
    Deba F; Ali HI; Tairu A; Ramos K; Ali J; Hamouda AK
    Sci Rep; 2018 Jan; 8(1):1249. PubMed ID: 29352227
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Unraveling amino acid residues critical for allosteric potentiation of (α4)3(β2)2-type nicotinic acetylcholine receptor responses.
    Wang ZJ; Deba F; Mohamed TS; Chiara DC; Ramos K; Hamouda AK
    J Biol Chem; 2017 Jun; 292(24):9988-10001. PubMed ID: 28446611
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of an intrasubunit nicotinic acetylcholine receptor-binding site for the positive allosteric modulator Br-PBTC.
    Norleans J; Wang J; Kuryatov A; Leffler A; Doebelin C; Kamenecka TM; Lindstrom J
    J Biol Chem; 2019 Aug; 294(32):12132-12145. PubMed ID: 31221718
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Desformylflustrabromine Modulates α4β2 Neuronal Nicotinic Acetylcholine Receptor High- and Low-Sensitivity Isoforms at Allosteric Clefts Containing the β2 Subunit.
    Weltzin MM; Schulte MK
    J Pharmacol Exp Ther; 2015 Aug; 354(2):184-94. PubMed ID: 26025967
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potentiation of (α4)2(β2)3, but not (α4)3(β2)2, nicotinic acetylcholine receptors reduces nicotine self-administration and withdrawal symptoms.
    Hamouda AK; Bautista MR; Akinola LS; Alkhlaif Y; Jackson A; Carper M; Toma WB; Garai S; Chen YC; Thakur GA; Fowler CD; Damaj MI
    Neuropharmacology; 2021 Jun; 190():108568. PubMed ID: 33878302
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Desformylflustrabromine (dFBr) and [3H]dFBr-Labeled Binding Sites in a Nicotinic Acetylcholine Receptor.
    Hamouda AK; Wang ZJ; Stewart DS; Jain AD; Glennon RA; Cohen JB
    Mol Pharmacol; 2015 Jul; 88(1):1-11. PubMed ID: 25870334
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Desformylflustrabromine (dFBr), a positive allosteric modulator of the α
    DeCristofano L; Decker S; Schulte MK; Suryanarayanan A
    Alcohol; 2021 Jun; 93():35-44. PubMed ID: 33652092
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Photolabeling a Nicotinic Acetylcholine Receptor (nAChR) with an (α4)3(β2)2 nAChR-Selective Positive Allosteric Modulator.
    Hamouda AK; Deba F; Wang ZJ; Cohen JB
    Mol Pharmacol; 2016 May; 89(5):575-84. PubMed ID: 26976945
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacological characterization of the allosteric modulator desformylflustrabromine and its interaction with alpha4beta2 neuronal nicotinic acetylcholine receptor orthosteric ligands.
    Weltzin MM; Schulte MK
    J Pharmacol Exp Ther; 2010 Sep; 334(3):917-26. PubMed ID: 20516140
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Orthosteric and allosteric potentiation of heteromeric neuronal nicotinic acetylcholine receptors.
    Wang J; Lindstrom J
    Br J Pharmacol; 2018 Jun; 175(11):1805-1821. PubMed ID: 28199738
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Examining the Effects of (α4)3(β2)2 Nicotinic Acetylcholine Receptor-Selective Positive Allosteric Modulator on Acute Thermal Nociception in Rats.
    Deba F; Ramos K; Vannoy M; Munoz K; Akinola LS; Damaj MI; Hamouda AK
    Molecules; 2020 Jun; 25(12):. PubMed ID: 32630476
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Desformylflustrabromine, a positive allosteric modulator of α4β2-containing nicotinic acetylcholine receptors, enhances cognition in rats.
    Nikiforuk A; Litwa E; Krawczyk M; Popik P; Arias H
    Pharmacol Rep; 2020 Jun; 72(3):589-599. PubMed ID: 32207091
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular interactions between mecamylamine enantiomers and the transmembrane domain of the human α4β2 nicotinic receptor.
    Bondarenko V; Targowska-Duda KM; Jozwiak K; Tang P; Arias HR
    Biochemistry; 2014 Feb; 53(5):908-18. PubMed ID: 24437521
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Allosteric modulation of α4β2* nicotinic acetylcholine receptors: Desformylflustrabromine potentiates antiallodynic response of nicotine in a mouse model of neuropathic pain.
    Bagdas D; Ergun D; Jackson A; Toma W; Schulte MK; Damaj MI
    Eur J Pain; 2018 Jan; 22(1):84-93. PubMed ID: 28809075
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Allosteric modulator Desformylflustrabromine relieves the inhibition of α2β2 and α4β2 nicotinic acetylcholine receptors by β-amyloid(1-42) peptide.
    Pandya A; Yakel JL
    J Mol Neurosci; 2011 Sep; 45(1):42-7. PubMed ID: 21424792
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assessing potentiation of the (α4)3(β2)2 nicotinic acetylcholine receptor by the allosteric agonist CMPI.
    Deba F; Munoz K; Peredia E; Akk G; Hamouda AK
    J Biol Chem; 2022 Jan; 298(1):101455. PubMed ID: 34861241
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Desformylflustrabromine: A Novel Positive Allosteric Modulator for beta2 Subunit Containing Nicotinic Receptor Sub-Types.
    Pandya AA
    Curr Pharm Des; 2016; 22(14):2057-63. PubMed ID: 26818864
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Non-agonist-binding subunit interfaces confer distinct functional signatures to the alternate stoichiometries of the alpha4beta2 nicotinic receptor: an alpha4-alpha4 interface is required for Zn2+ potentiation.
    Moroni M; Vijayan R; Carbone A; Zwart R; Biggin PC; Bermudez I
    J Neurosci; 2008 Jul; 28(27):6884-94. PubMed ID: 18596163
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Unorthodox Acetylcholine Binding Sites Formed by α5 and β3 Accessory Subunits in α4β2* Nicotinic Acetylcholine Receptors.
    Jain A; Kuryatov A; Wang J; Kamenecka TM; Lindstrom J
    J Biol Chem; 2016 Nov; 291(45):23452-23463. PubMed ID: 27645992
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors.
    Olsen JA; Ahring PK; Kastrup JS; Gajhede M; Balle T
    J Biol Chem; 2014 Sep; 289(36):24911-21. PubMed ID: 24982426
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.