BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 29355491)

  • 1. Restoration of mutant hERG stability by inhibition of HDAC6.
    Li P; Kurata Y; Endang M; Ninomiya H; Higaki K; Taufiq F; Morikawa K; Shirayoshi Y; Horie M; Hisatome I
    J Mol Cell Cardiol; 2018 Feb; 115():158-169. PubMed ID: 29355491
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins.
    Iwai C; Li P; Kurata Y; Hoshikawa Y; Morikawa K; Maharani N; Higaki K; Sasano T; Notsu T; Ishido Y; Miake J; Yamamoto Y; Shirayoshi Y; Ninomiya H; Nakai A; Murata S; Yoshida A; Yamamoto K; Hiraoka M; Hisatome I
    Cardiovasc Res; 2013 Dec; 100(3):520-8. PubMed ID: 23963841
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG.
    Ficker E; Dennis AT; Wang L; Brown AM
    Circ Res; 2003 Jun; 92(12):e87-100. PubMed ID: 12775586
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential Regulation of Human Ether-à-Go-Go-Related Gene (hERG) Current and Expression by Activation of Protein Kinase C.
    Sutherland-Deveen ME; Wang T; Lamothe SM; Tschirhart JN; Guo J; Li W; Yang T; Du Y; Zhang S
    Mol Pharmacol; 2019 Jul; 96(1):1-12. PubMed ID: 31015282
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacologic Approach to Defective Protein Trafficking in the E637K-hERG Mutant with PD-118057 and Thapsigargin.
    Mao H; Lu X; Karush JM; Huang X; Yang X; Ba Y; Wang Y; Liu N; Zhou J; Lian J
    PLoS One; 2013; 8(6):e65481. PubMed ID: 23840331
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel.
    Furutani M; Trudeau MC; Hagiwara N; Seki A; Gong Q; Zhou Z; Imamura S; Nagashima H; Kasanuki H; Takao A; Momma K; January CT; Robertson GA; Matsuoka R
    Circulation; 1999 May; 99(17):2290-4. PubMed ID: 10226095
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential Effects of Remdesivir and Lumacaftor on Homomeric and Heteromeric hERG Channels.
    Campagna N; Wall E; Lee K; Guo J; Li W; Yang T; Baranchuk A; El-Diasty M; Zhang S
    Mol Pharmacol; 2023 Oct; 104(4):164-173. PubMed ID: 37419691
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Histone deacetylase 6 inhibitor tubastatin A attenuates angiotensin II-induced hypertension by preventing cystathionine γ-lyase protein degradation.
    Chi Z; Byeon HE; Seo E; Nguyen QT; Lee W; Jeong Y; Choi J; Pandey D; Berkowitz DE; Kim JH; Lee SY
    Pharmacol Res; 2019 Aug; 146():104281. PubMed ID: 31125601
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Trafficking-deficient G572R-hERG and E637K-hERG activate stress and clearance pathways in endoplasmic reticulum.
    Wang Y; Huang X; Zhou J; Yang X; Li D; Mao H; Sun HH; Liu N; Lian J
    PLoS One; 2012; 7(1):e29885. PubMed ID: 22242185
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anti-Ro52 antibody acts on the S5-pore linker of hERG to chronically reduce channel expression.
    Szendrey J; Lamothe SM; Vanner S; Guo J; Yang T; Li W; Davis J; Joneja M; Baranchuk A; Zhang S
    Cardiovasc Res; 2019 Aug; 115(10):1500-1511. PubMed ID: 30544220
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Properties of WT and mutant hERG K(+) channels expressed in neonatal mouse cardiomyocytes.
    Lin EC; Holzem KM; Anson BD; Moungey BM; Balijepalli SY; Tester DJ; Ackerman MJ; Delisle BP; Balijepalli RC; January CT
    Am J Physiol Heart Circ Physiol; 2010 Jun; 298(6):H1842-9. PubMed ID: 20363883
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Serine mutation of a conserved threonine in the hERG K
    Al-Moubarak E; Zhang Y; Dempsey CE; Zhang H; Harmer SC; Hancox JC
    Biochem Biophys Res Commun; 2020 Jun; 526(4):1085-1091. PubMed ID: 32321643
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER.
    Smith JL; McBride CM; Nataraj PS; Bartos DC; January CT; Delisle BP
    Am J Physiol Cell Physiol; 2011 Jul; 301(1):C75-85. PubMed ID: 21490315
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intracellular Mechanism of Rosuvastatin-Induced Decrease in Mature hERG Protein Expression on Membrane.
    Feng PF; Zhang B; Zhao L; Fang Q; Liu Y; Wang JN; Xu XQ; Xue H; Li Y; Yan CC; Zhao X; Li BX
    Mol Pharm; 2019 Apr; 16(4):1477-1488. PubMed ID: 30807184
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Trafficking of the human ether-a-go-go-related gene (hERG) potassium channel is regulated by the ubiquitin ligase rififylin (RFFL).
    Roder K; Kabakov A; Moshal KS; Murphy KR; Xie A; Dudley S; Turan NN; Lu Y; MacRae CA; Koren G
    J Biol Chem; 2019 Jan; 294(1):351-360. PubMed ID: 30401747
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological correction of long QT-linked mutations in KCNH2 (hERG) increases the trafficking of Kv11.1 channels stored in the transitional endoplasmic reticulum.
    Smith JL; Reloj AR; Nataraj PS; Bartos DC; Schroder EA; Moss AJ; Ohno S; Horie M; Anderson CL; January CT; Delisle BP
    Am J Physiol Cell Physiol; 2013 Nov; 305(9):C919-30. PubMed ID: 23864605
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypoxia reduces mature hERG channels through calpain up-regulation.
    Lamothe SM; Song W; Guo J; Li W; Yang T; Baranchuk A; Graham CH; Zhang S
    FASEB J; 2017 Nov; 31(11):5068-5077. PubMed ID: 28784631
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PTEN activation through K163 acetylation by inhibiting HDAC6 contributes to tumour inhibition.
    Meng Z; Jia LF; Gan YH
    Oncogene; 2016 May; 35(18):2333-44. PubMed ID: 26279303
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Human Ether-a-go-go-related Gene (hERG) Potassium Channel Represents an Unusual Target for Protease-mediated Damage.
    Lamothe SM; Guo J; Li W; Yang T; Zhang S
    J Biol Chem; 2016 Sep; 291(39):20387-401. PubMed ID: 27502273
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    Sangoi MG; Lamothe SM; Guo J; Yang T; Li W; Avery EG; Fisher JT; Zhang S
    Mol Pharmacol; 2017 Aug; 92(2):162-174. PubMed ID: 28495999
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.