These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 29358310)

  • 1. 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio) hexanol: a promising new anticancer compound.
    Sha HH; Wang Z; Dong SC; Hu TM; Liu SW; Zhang JY; Wu Y; Ma R; Wu JZ; Chen D; Feng JF
    Biosci Rep; 2018 Feb; 38(1):. PubMed ID: 29358310
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for the binding of the anticancer compound 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol to human glutathione s-transferases.
    Federici L; Lo Sterzo C; Pezzola S; Di Matteo A; Scaloni F; Federici G; Caccuri AM
    Cancer Res; 2009 Oct; 69(20):8025-34. PubMed ID: 19808963
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro and in vivo efficacy of 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) on human melanoma.
    Pellizzari Tregno F; Sau A; Pezzola S; Geroni C; Lapenta C; Spada M; Filomeni G; Bonanno E; Federici G; Caccuri AM
    Eur J Cancer; 2009 Sep; 45(14):2606-17. PubMed ID: 19665369
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol, a specific glutathione S-transferase inhibitor, overcomes the multidrug resistance (MDR)-associated protein 1-mediated MDR in small cell lung cancer.
    Filomeni G; Turella P; Dupuis ML; Forini O; Ciriolo MR; Cianfriglia M; Pezzola S; Federici G; Caccuri AM
    Mol Cancer Ther; 2008 Feb; 7(2):371-9. PubMed ID: 18281520
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 7-Nitro-2,1,3-benzoxadiazole derivatives, a new class of suicide inhibitors for glutathione S-transferases. Mechanism of action of potential anticancer drugs.
    Ricci G; De Maria F; Antonini G; Turella P; Bullo A; Stella L; Filomeni G; Federici G; Caccuri AM
    J Biol Chem; 2005 Jul; 280(28):26397-405. PubMed ID: 15888444
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A strong glutathione S-transferase inhibitor overcomes the P-glycoprotein-mediated resistance in tumor cells. 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) triggers a caspase-dependent apoptosis in MDR1-expressing leukemia cells.
    Turella P; Filomeni G; Dupuis ML; Ciriolo MR; Molinari A; De Maria F; Tombesi M; Cianfriglia M; Federici G; Ricci G; Caccuri AM
    J Biol Chem; 2006 Aug; 281(33):23725-32. PubMed ID: 16769721
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overcoming glutathione S-transferase P1-related cisplatin resistance in osteosarcoma.
    Pasello M; Michelacci F; Scionti I; Hattinger CM; Zuntini M; Caccuri AM; Scotlandi K; Picci P; Serra M
    Cancer Res; 2008 Aug; 68(16):6661-8. PubMed ID: 18701490
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines.
    Sau A; Filomeni G; Pezzola S; D'Aguanno S; Tregno FP; Urbani A; Serra M; Pasello M; Picci P; Federici G; Caccuri AM
    Mol Biosyst; 2012 Apr; 8(4):994-1006. PubMed ID: 22068640
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proapoptotic activity of new glutathione S-transferase inhibitors.
    Turella P; Cerella C; Filomeni G; Bullo A; De Maria F; Ghibelli L; Ciriolo MR; Cianfriglia M; Mattei M; Federici G; Ricci G; Caccuri AM
    Cancer Res; 2005 May; 65(9):3751-61. PubMed ID: 15867371
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The glutathione S-transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol overcomes the MDR1-P-glycoprotein and MRP1-mediated multidrug resistance in acute myeloid leukemia cells.
    Ascione A; Cianfriglia M; Dupuis ML; Mallano A; Sau A; Pellizzari Tregno F; Pezzola S; Caccuri AM
    Cancer Chemother Pharmacol; 2009 Jul; 64(2):419-24. PubMed ID: 19288261
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.
    Tentori L; Dorio AS; Mazzon E; Muzi A; Sau A; Cuzzocrea S; Vernole P; Federici G; Caccuri AM; Graziani G
    Eur J Cancer; 2011 May; 47(8):1219-30. PubMed ID: 21269821
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol Derivatives as Glutathione Transferase Inhibitors with Favorable Selectivity and Tolerated Toxicity.
    Liu Q; Liu Z; Hua W; Gou S
    J Med Chem; 2021 Feb; 64(3):1701-1712. PubMed ID: 33529017
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A cisplatin-based platinum(IV) prodrug containing a glutathione s-transferase inhibitor to reverse cisplatin-resistance in non-small cell lung cancer.
    Chen H; Wang X; Gou S
    J Inorg Biochem; 2019 Apr; 193():133-142. PubMed ID: 30731264
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NBDHEX re-sensitizes adriamycin-resistant breast cancer by inhibiting glutathione S-transferase pi.
    Sha H; Zou R; Lu Y; Gan Y; Ma R; Feng J; Chen D
    Cancer Med; 2023 Mar; 12(5):5833-5845. PubMed ID: 36266920
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overcoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcome.
    Scotlandi K; Remondini D; Castellani G; Manara MC; Nardi F; Cantiani L; Francesconi M; Mercuri M; Caccuri AM; Serra M; Knuutila S; Picci P
    J Clin Oncol; 2009 May; 27(13):2209-16. PubMed ID: 19307502
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio) Hexanol Inhibits Proliferation and Induces Apoptosis of Endometriosis by Regulating Glutathione S-Transferase Mu Class 4.
    Liu W; Cheng L; Du Y; Liu X; Ma J; Yan L
    Reprod Sci; 2023 Oct; 30(10):2945-2961. PubMed ID: 36928896
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts.
    De Luca A; Rotili D; Carpanese D; Lenoci A; Calderan L; Scimeca M; Mai A; Bonanno E; Rosato A; Geroni C; Quintieri L; Caccuri AM
    Oncotarget; 2015 Feb; 6(6):4126-43. PubMed ID: 25595904
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: a promising therapeutic strategy.
    Pasello M; Manara MC; Michelacci F; Fanelli M; Hattinger CM; Nicoletti G; Landuzzi L; Lollini PL; Caccuri A; Picci P; Scotlandi K; Serra M
    Anal Cell Pathol (Amst); 2011; 34(3):131-45. PubMed ID: 21673434
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of Glutathione Transferase-Targeting Nitrobenzoxadiazole Compounds in Relation to PD-L1 Status in Human Melanoma Cells.
    Sciarretta F; Fulci C; Palumbo C; Rotili D; Tentori L; Graziani G; Caccuri AM
    Chemotherapy; 2019; 64(3):138-145. PubMed ID: 31639786
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective inhibitors of glutathione transferase P1 with trioxane structure as anticancer agents.
    Bräutigam M; Teusch N; Schenk T; Sheikh M; Aricioglu RZ; Borowski SH; Neudörfl JM; Baumann U; Griesbeck AG; Pietsch M
    ChemMedChem; 2015 Apr; 10(4):629-39. PubMed ID: 25694385
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.