BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

386 related articles for article (PubMed ID: 29359764)

  • 1. Structure-based inhibitors of tau aggregation.
    Seidler PM; Boyer DR; Rodriguez JA; Sawaya MR; Cascio D; Murray K; Gonen T; Eisenberg DS
    Nat Chem; 2018 Feb; 10(2):170-176. PubMed ID: 29359764
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples.
    Seidler PM; Boyer DR; Murray KA; Yang TP; Bentzel M; Sawaya MR; Rosenberg G; Cascio D; Williams CK; Newell KL; Ghetti B; DeTure MA; Dickson DW; Vinters HV; Eisenberg DS
    J Biol Chem; 2019 Nov; 294(44):16451-16464. PubMed ID: 31537646
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.
    Stöhr J; Wu H; Nick M; Wu Y; Bhate M; Condello C; Johnson N; Rodgers J; Lemmin T; Acharya S; Becker J; Robinson K; Kelly MJS; Gai F; Stubbs G; Prusiner SB; DeGrado WF
    Nat Chem; 2017 Sep; 9(9):874-881. PubMed ID: 28837163
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conformation determines the seeding potencies of native and recombinant Tau aggregates.
    Falcon B; Cavallini A; Angers R; Glover S; Murray TK; Barnham L; Jackson S; O'Neill MJ; Isaacs AM; Hutton ML; Szekeres PG; Goedert M; Bose S
    J Biol Chem; 2015 Jan; 290(2):1049-65. PubMed ID: 25406315
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural study of the recognition mechanism of tau antibody Tau2r3 with the key sequence (VQIINK) in tau aggregation.
    Tsuchida T; Susa K; Kibiki T; Tsuchiya T; Miyamoto K; In Y; Minoura K; Taniguchi T; Ishida T; Tomoo K
    Biochem Biophys Res Commun; 2021 Dec; 585():36-41. PubMed ID: 34784549
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of tau amyloid formation and disruption of its preformed fibrils by Naphthoquinone-Dopamine hybrid.
    Paul A; Viswanathan GK; Huber A; Arad E; Engel H; Jelinek R; Gazit E; Segal D
    FEBS J; 2021 Jul; 288(14):4267-4290. PubMed ID: 33523571
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Integrating in vitro and in silico approaches to evaluate the "dual functionality" of palmatine chloride in inhibiting and disassembling Tau-derived VQIVYK peptide fibrils.
    Haj E; Losev Y; Guru KrishnaKumar V; Pichinuk E; Engel H; Raveh A; Gazit E; Segal D
    Biochim Biophys Acta Gen Subj; 2018 Jul; 1862(7):1565-1575. PubMed ID: 29634991
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tau R2 and R3 are essential regions for tau aggregation, seeding and propagation.
    Annadurai N; Malina L; Malohlava J; Hajdúch M; Das V
    Biochimie; 2022 Sep; 200():79-86. PubMed ID: 35623497
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of tau domain-specific antibodies and intravenous immunoglobulin on tau aggregation and aggregate degradation.
    Esteves-Villanueva JO; Trzeciakiewicz H; Loeffler DA; Martić S
    Biochemistry; 2015 Jan; 54(2):293-302. PubMed ID: 25545358
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanistic insights into remodeled Tau-derived PHF6 peptide fibrils by Naphthoquinone-Tryptophan hybrids.
    KrishnaKumar VG; Paul A; Gazit E; Segal D
    Sci Rep; 2018 Jan; 8(1):71. PubMed ID: 29311706
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of cellular polyanion mimetics on tau peptide aggregation.
    Ismail T; Kanapathipillai M
    J Pept Sci; 2018 Nov; 24(11):e3125. PubMed ID: 30251388
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparison of size distribution and (Pro249-Ser258) epitope exposure in in vitro and in vivo derived Tau fibrils.
    Marreiro A; Van Kolen K; Sousa C; Temmerman L; Vasconcelos B; Crespo-Rodriguez R; van Weering JRT; Van Dam D; De Deyn PP; Apetri A; Schoofs L; Mercken MH
    BMC Mol Cell Biol; 2020 Nov; 21(1):81. PubMed ID: 33183222
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tau peptides and tau mutant protein aggregation inhibition by cationic polyethyleneimine and polyarginine.
    Nadimidla K; Ismail T; Kanapathipillai M
    Biopolymers; 2017 Sep; 107(9):. PubMed ID: 28456996
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Potent Tau Aggregation Inhibitor D-Peptides Selected against Tau-Repeat 2 Using Mirror Image Phage Display.
    Malhis M; Kaniyappan S; Aillaud I; Chandupatla RR; Ramirez LM; Zweckstetter M; Horn AHC; Mandelkow E; Sticht H; Funke SA
    Chembiochem; 2021 Nov; 22(21):3049-3059. PubMed ID: 34375027
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of tau aggregation using a naturally-occurring cyclic peptide scaffold.
    Wang CK; Northfield SE; Huang YH; Ramos MC; Craik DJ
    Eur J Med Chem; 2016 Feb; 109():342-9. PubMed ID: 26807864
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inert and seed-competent tau monomers suggest structural origins of aggregation.
    Mirbaha H; Chen D; Morazova OA; Ruff KM; Sharma AM; Liu X; Goodarzi M; Pappu RV; Colby DW; Mirzaei H; Joachimiak LA; Diamond MI
    Elife; 2018 Jul; 7():. PubMed ID: 29988016
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Can any "non-specific charge modification within microtubule binding domains of Tau" be a prerequisite of the protein amyloid aggregation? An in vitro study on the 1N4R isoform.
    Jangholi A; Ashrafi-Kooshk MR; Arab SS; Karima S; Poorebrahim M; Ghadami SA; Moosavi-Movahedi AA; Khodarahmi R
    Int J Biol Macromol; 2018 Apr; 109():188-204. PubMed ID: 29248553
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Understanding the disrupting mechanism of the Tau aggregation motif "
    Moreno-Castillo E; Álvarez-Ginarte YM; Valdés-Tresanco ME; Montero-Cabrera LA; Moreno E; Valiente PA
    J Mol Recognit; 2020 Sep; 33(9):e2848. PubMed ID: 32227525
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cellular Models of Aggregation-dependent Template-directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer Disease.
    Harrington CR; Storey JM; Clunas S; Harrington KA; Horsley D; Ishaq A; Kemp SJ; Larch CP; Marshall C; Nicoll SL; Rickard JE; Simpson M; Sinclair JP; Storey LJ; Wischik CM
    J Biol Chem; 2015 Apr; 290(17):10862-75. PubMed ID: 25759392
    [TBL] [Abstract][Full Text] [Related]  

  • 20. De novo designed protein inhibitors of amyloid aggregation and seeding.
    Murray KA; Hu CJ; Griner SL; Pan H; Bowler JT; Abskharon R; Rosenberg GM; Cheng X; Seidler PM; Eisenberg DS
    Proc Natl Acad Sci U S A; 2022 Aug; 119(34):e2206240119. PubMed ID: 35969734
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.