These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 29362425)

  • 1. Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination.
    Acosta MI; Urbach S; Doye A; Ng YW; Boudeau J; Mettouchi A; Debant A; Manser E; Visvikis O; Lemichez E
    Sci Rep; 2018 Jan; 8(1):1410. PubMed ID: 29362425
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The E3 ubiquitin-ligase HACE1 catalyzes the ubiquitylation of active Rac1.
    Torrino S; Visvikis O; Doye A; Boyer L; Stefani C; Munro P; Bertoglio J; Gacon G; Mettouchi A; Lemichez E
    Dev Cell; 2011 Nov; 21(5):959-65. PubMed ID: 22036506
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oxygen sensor FIH inhibits HACE1-dependent ubiquitination of Rac1 to enhance metastatic potential in breast cancer cells.
    Kim I; Shin SH; Lee JE; Park JW
    Oncogene; 2019 May; 38(19):3651-3666. PubMed ID: 30659265
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.
    Andrio E; Lotte R; Hamaoui D; Cherfils J; Doye A; Daugaard M; Sorensen PH; Bost F; Ruimy R; Mettouchi A; Lemichez E
    Sci Rep; 2017 Mar; 7():44779. PubMed ID: 28317937
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ubiquitylation of active Rac1 by the E3 ubiquitin-ligase HACE1.
    Mettouchi A; Lemichez E
    Small GTPases; 2012; 3(2):102-6. PubMed ID: 22790197
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HACE1 negatively regulates neuroinflammation through ubiquitylating and degrading Rac1 in Parkinson's disease models.
    Zang CX; Wang L; Yang HY; Shang JM; Liu H; Zhang ZH; Ju C; Yuan FY; Li FY; Bao XQ; Zhang D
    Acta Pharmacol Sin; 2022 Feb; 43(2):285-294. PubMed ID: 34593974
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The tumour suppressor HACE1 controls cell migration by regulating Rac1 degradation.
    Castillo-Lluva S; Tan CT; Daugaard M; Sorensen PH; Malliri A
    Oncogene; 2013 Mar; 32(13):1735-42. PubMed ID: 22614015
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes.
    Turgu B; El-Naggar A; Kogler M; Tortola L; Zhang HF; Hassan M; Lizardo MM; Kung SH; Lam W; Penninger JM; Sorensen PH
    EMBO Rep; 2023 Dec; 24(12):e56815. PubMed ID: 37846480
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [The tumor suppressor HACE1 targets Rac1 to ubiquitin-mediated proteasomal degradation].
    Gacon G; Mettouchi A; Lemichez E
    Med Sci (Paris); 2012 Jan; 28(1):39-41. PubMed ID: 22289828
    [No Abstract]   [Full Text] [Related]  

  • 10. p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase.
    Barrows D; Schoenfeld SM; Hodakoski C; Silkov A; Honig B; Couvillon A; Shymanets A; Nürnberg B; Asara JM; Parsons R
    J Biol Chem; 2015 Nov; 290(48):28915-31. PubMed ID: 26438819
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.
    Turgu B; Zhang F; El-Naggar A; Negri GL; Kogler M; Tortola L; Johnson F; Ng T; Li A; Yapp D; Lockwood W; Martinez D; Maris JM; Daugaard M; Penninger JM; Hughes CS; Sorensen PH
    Oncogene; 2021 Mar; 40(11):1988-2001. PubMed ID: 33603169
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.
    Kogler M; Tortola L; Negri GL; Leopoldi A; El-Naggar AM; Mereiter S; Gomez-Diaz C; Nitsch R; Tortora D; Kavirayani AM; Gapp BV; Rao S; Uribesalgo I; Hoffmann D; Cikes D; Novatchkova M; Williams DA; Trent JM; Ikeda F; Daugaard M; Hagelkruys A; Sorensen PH; Penninger JM
    Cancer Res; 2020 Jul; 80(14):3009-3022. PubMed ID: 32366477
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Uncovering and deciphering the pro-invasive role of HACE1 in melanoma cells.
    El-Hachem N; Habel N; Naiken T; Bzioueche H; Cheli Y; Beranger GE; Jaune E; Rouaud F; Nottet N; Reinier F; Gaudel C; Colosetti P; Bertolotto C; Ballotti R
    Cell Death Differ; 2018 Nov; 25(11):2010-2022. PubMed ID: 29515254
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 14-3-3beta-Rac1-p21 activated kinase signaling regulates Akt1-mediated cytoskeletal organization, lamellipodia formation and fibronectin matrix assembly.
    Somanath PR; Byzova TV
    J Cell Physiol; 2009 Feb; 218(2):394-404. PubMed ID: 18853424
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation of Threonine 794 on Tie1 by Rac1/PAK1 Reveals a Novel Angiogenesis Regulatory Pathway.
    Reinardy JL; Corey DM; Golzio C; Mueller SB; Katsanis N; Kontos CD
    PLoS One; 2015; 10(10):e0139614. PubMed ID: 26436659
    [TBL] [Abstract][Full Text] [Related]  

  • 16. IAPs as E3 ligases of Rac1: shaping the move.
    Oberoi-Khanuja TK; Rajalingam K
    Small GTPases; 2012; 3(2):131-6. PubMed ID: 22790203
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HACE1 is a potential tumor suppressor in osteosarcoma.
    El-Naggar AM; Clarkson PW; Negri GL; Turgu B; Zhang F; Anglesio MS; Sorensen PH
    Cell Death Dis; 2019 Jan; 10(1):21. PubMed ID: 30622235
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1.
    Düring J; Wolter M; Toplak JJ; Torres C; Dybkov O; Fokkens TJ; Bohnsack KE; Urlaub H; Steinchen W; Dienemann C; Lorenz S
    Nat Struct Mol Biol; 2024 Feb; 31(2):364-377. PubMed ID: 38332367
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of esophageal cancer progression through HACE1-TRIP12 interaction and associated RAC1 ubiquitination and degradation.
    Hu Y; Zhu Z; Xu Y; Zaman MF; Ge Y; Hu J; Tang X
    J Cancer; 2024; 15(10):3114-3127. PubMed ID: 38706891
    [No Abstract]   [Full Text] [Related]  

  • 20. Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
    Daugaard M; Nitsch R; Razaghi B; McDonald L; Jarrar A; Torrino S; Castillo-Lluva S; Rotblat B; Li L; Malliri A; Lemichez E; Mettouchi A; Berman JN; Penninger JM; Sorensen PH
    Nat Commun; 2013; 4():2180. PubMed ID: 23864022
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.