BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

368 related articles for article (PubMed ID: 29366807)

  • 1. Bioactivity and gene expression profiles of hiPSC-generated retinal ganglion cells in MT-ND4 mutated Leber's hereditary optic neuropathy.
    Wu YR; Wang AG; Chen YT; Yarmishyn AA; Buddhakosai W; Yang TC; Hwang DK; Yang YP; Shen CN; Lee HC; Chiou SH; Peng CH; Chen SJ
    Exp Cell Res; 2018 Feb; 363(2):299-309. PubMed ID: 29366807
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitochondrial transport mediates survival of retinal ganglion cells in affected LHON patients.
    Yang TC; Yarmishyn AA; Yang YP; Lu PC; Chou SJ; Wang ML; Lin TC; Hwang DK; Chou YB; Chen SJ; Yu WK; Wang AG; Hsu CC; Chiou SH
    Hum Mol Genet; 2020 Jun; 29(9):1454-1464. PubMed ID: 32277753
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glutamate Stimulation Dysregulates AMPA Receptors-Induced Signal Transduction Pathway in Leber's Inherited Optic Neuropathy Patient-Specific hiPSC-Derived Retinal Ganglion Cells.
    Yang YP; Nguyen PNN; Lin TC; Yarmishyn AA; Chen WS; Hwang DK; Chiou GY; Lin TW; Chien CS; Tsai CY; Chiou SH; Chen SJ; Peng CH; Hsu CC
    Cells; 2019 Jun; 8(6):. PubMed ID: 31234430
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Generation of a human iPSC line, FINCBi001-A, carrying a homoplasmic m.G3460A mutation in MT-ND1 associated with Leber's Hereditary optic Neuropathy (LHON).
    Peron C; Mauceri R; Cabassi T; Segnali A; Maresca A; Iannielli A; Rizzo A; Sciacca FL; Broccoli V; Carelli V; Tiranti V
    Stem Cell Res; 2020 Oct; 48():101939. PubMed ID: 32771908
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Generation of an induced pluripotent stem cell line from a patient with leber's hereditary optic neuropathy carrying a homoplasmic m.3635G > A mutation in the mitochondrial ND1 gene.
    Ji D; Su X; Hu C; Zhang Z; Wang M; Zou W; Shen L; Liu Y; Liang C; Du Y; Liang D; Cao Y
    Stem Cell Res; 2022 Aug; 63():102858. PubMed ID: 35905669
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Leber's Hereditary Optic Neuropathy as a Promising Disease for Gene Therapy Development.
    Karaarslan C
    Adv Ther; 2019 Dec; 36(12):3299-3307. PubMed ID: 31605306
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitochondrial replacement in an iPSC model of Leber's hereditary optic neuropathy.
    Wong RCB; Lim SY; Hung SSC; Jackson S; Khan S; Van Bergen NJ; De Smit E; Liang HH; Kearns LS; Clarke L; Mackey DA; Hewitt AW; Trounce IA; Pébay A
    Aging (Albany NY); 2017 Apr; 9(4):1341-1350. PubMed ID: 28455970
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Emerging model systems and treatment approaches for Leber's hereditary optic neuropathy: Challenges and opportunities.
    Bahr T; Welburn K; Donnelly J; Bai Y
    Biochim Biophys Acta Mol Basis Dis; 2020 Jun; 1866(6):165743. PubMed ID: 32105823
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Abnormal morphology and function in retinal ganglion cells derived from patients-specific iPSCs generated from individuals with Leber's hereditary optic neuropathy.
    Nie Z; Wang C; Chen J; Ji Y; Zhang H; Zhao F; Zhou X; Guan MX
    Hum Mol Genet; 2023 Jan; 32(2):231-243. PubMed ID: 35947995
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nuclear modifier YARS2 allele correction restored retinal ganglion cells-specific deficiencies in Leber's hereditary optic neuropathy.
    Chen JR; Chen C; Chen J; Ji Y; Lian Y; Zhang J; Yu J; Li XY; Qu J; Guan MX
    Hum Mol Genet; 2023 Apr; 32(9):1539-1551. PubMed ID: 36611011
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LHON gene therapy vector prevents visual loss and optic neuropathy induced by G11778A mutant mitochondrial DNA: biodistribution and toxicology profile.
    Koilkonda R; Yu H; Talla V; Porciatti V; Feuer WJ; Hauswirth WW; Chiodo V; Erger KE; Boye SL; Lewin AS; Conlon TJ; Renner L; Neuringer M; Detrisac C; Guy J
    Invest Ophthalmol Vis Sci; 2014 Oct; 55(12):7739-53. PubMed ID: 25342621
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Efficient mitochondrial biogenesis drives incomplete penetrance in Leber's hereditary optic neuropathy.
    Giordano C; Iommarini L; Giordano L; Maresca A; Pisano A; Valentino ML; Caporali L; Liguori R; Deceglie S; Roberti M; Fanelli F; Fracasso F; Ross-Cisneros FN; D'Adamo P; Hudson G; Pyle A; Yu-Wai-Man P; Chinnery PF; Zeviani M; Salomao SR; Berezovsky A; Belfort R; Ventura DF; Moraes M; Moraes Filho M; Barboni P; Sadun F; De Negri A; Sadun AA; Tancredi A; Mancini M; d'Amati G; Loguercio Polosa P; Cantatore P; Carelli V
    Brain; 2014 Feb; 137(Pt 2):335-53. PubMed ID: 24369379
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting estrogen receptor β as preventive therapeutic strategy for Leber's hereditary optic neuropathy.
    Pisano A; Preziuso C; Iommarini L; Perli E; Grazioli P; Campese AF; Maresca A; Montopoli M; Masuelli L; Sadun AA; d'Amati G; Carelli V; Ghelli A; Giordano C
    Hum Mol Genet; 2015 Dec; 24(24):6921-31. PubMed ID: 26410888
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells.
    Hung SS; Van Bergen NJ; Jackson S; Liang H; Mackey DA; Hernández D; Lim SY; Hewitt AW; Trounce I; Pébay A; Wong RC
    Aging (Albany NY); 2016 May; 8(5):945-57. PubMed ID: 27127184
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The metabolomic signature of Leber's hereditary optic neuropathy reveals endoplasmic reticulum stress.
    Chao de la Barca JM; Simard G; Amati-Bonneau P; Safiedeen Z; Prunier-Mirebeau D; Chupin S; Gadras C; Tessier L; Gueguen N; Chevrollier A; Desquiret-Dumas V; Ferré M; Bris C; Kouassi Nzoughet J; Bocca C; Leruez S; Verny C; Miléa D; Bonneau D; Lenaers G; Martinez MC; Procaccio V; Reynier P
    Brain; 2016 Nov; 139(11):2864-2876. PubMed ID: 27633772
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Generation of patient-specific induced pluripotent stem cells from Leber's hereditary optic neuropathy.
    Lu HE; Yang YP; Chen YT; Wu YR; Wang CL; Tsai FT; Hwang DK; Lin TC; Chen SJ; Wang AG; Hsieh PCH; Chiou SH
    Stem Cell Res; 2018 Apr; 28():56-60. PubMed ID: 29427840
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oestrogens ameliorate mitochondrial dysfunction in Leber's hereditary optic neuropathy.
    Giordano C; Montopoli M; Perli E; Orlandi M; Fantin M; Ross-Cisneros FN; Caparrotta L; Martinuzzi A; Ragazzi E; Ghelli A; Sadun AA; d'Amati G; Carelli V
    Brain; 2011 Jan; 134(Pt 1):220-34. PubMed ID: 20943885
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Retinal Circular RNA hsa_circ_0087207 Expression Promotes Apoptotic Cell Death in Induced Pluripotent Stem Cell-Derived Leber's Hereditary Optic Neuropathy-like Models.
    Yang YP; Chang YL; Lai YH; Tsai PH; Hsiao YJ; Nguyen LH; Lim XZ; Weng CC; Ko YL; Yang CH; Hwang DK; Chen SJ; Chiou SH; Chiou GY; Wang AG; Chien Y
    Biomedicines; 2022 Mar; 10(4):. PubMed ID: 35453537
    [No Abstract]   [Full Text] [Related]  

  • 19. Pathological mitophagy disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy.
    Danese A; Patergnani S; Maresca A; Peron C; Raimondi A; Caporali L; Marchi S; La Morgia C; Del Dotto V; Zanna C; Iannielli A; Segnali A; Di Meo I; Cavaliere A; Lebiedzinska-Arciszewska M; Wieckowski MR; Martinuzzi A; Moraes-Filho MN; Salomao SR; Berezovsky A; Belfort R; Buser C; Ross-Cisneros FN; Sadun AA; Tacchetti C; Broccoli V; Giorgi C; Tiranti V; Carelli V; Pinton P
    Cell Rep; 2022 Jul; 40(3):111124. PubMed ID: 35858578
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Contribution of mitochondrial ND1 3394T>C mutation to the phenotypic manifestation of Leber's hereditary optic neuropathy.
    Ji Y; Zhang J; Yu J; Wang Y; Lu Y; Liang M; Li Q; Jin X; Wei Y; Meng F; Gao Y; Cang X; Tong Y; Liu X; Zhang M; Jiang P; Zhu T; Mo JQ; Huang T; Jiang P; Guan MX
    Hum Mol Genet; 2019 May; 28(9):1515-1529. PubMed ID: 30597069
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.