BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

432 related articles for article (PubMed ID: 29367077)

  • 1. Synthesis, anticancer assessment on human breast, liver and colon carcinoma cell lines and molecular modeling study using novel pyrazolo[4,3-c]pyridine derivatives.
    Metwally NH; Deeb EA
    Bioorg Chem; 2018 Apr; 77():203-214. PubMed ID: 29367077
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tyrosine kinase inhibition effects of novel Pyrazolo[1,5-a]pyrimidines and Pyrido[2,3-d]pyrimidines ligand: Synthesis, biological screening and molecular modeling studies.
    El Sayed MT; Hussein HAR; Elebiary NM; Hassan GS; Elmessery SM; Elsheakh AR; Nayel M; Abdel-Aziz HA
    Bioorg Chem; 2018 Aug; 78():312-323. PubMed ID: 29625271
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, molecular modeling and biological evaluation of novel 1H-pyrazolo[3,4-b]pyridine derivatives as potential anticancer agents.
    Eissa IH; El-Naggar AM; El-Hashash MA
    Bioorg Chem; 2016 Aug; 67():43-56. PubMed ID: 27253830
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3-Aminopyrazolo[3,4-b]pyridine: Effective Precursor for Barium Hydroxide-Mediated Three Components Synthesis of New Mono- and Bis(pyrimidines) with Potential Cytotoxic Activity.
    Sanad SMH; Mekky AEM
    Chem Biodivers; 2022 Jan; 19(1):e202100500. PubMed ID: 34784450
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel Pyrazolo[3,4-d]pyrimidines as Potential Cytotoxic Agents: Design, Synthesis, Molecular Docking and CDK2 Inhibition.
    Maher M; Kassab AE; Zaher AF; Mahmoud Z
    Anticancer Agents Med Chem; 2019; 19(11):1368-1381. PubMed ID: 31038080
    [TBL] [Abstract][Full Text] [Related]  

  • 6. One-pot three-component synthesis of novel pyrazolo[3,4-b]pyridines as potent antileukemic agents.
    Barghash RF; Eldehna WM; Kovalová M; Vojáčková V; Kryštof V; Abdel-Aziz HA
    Eur J Med Chem; 2022 Jan; 227():113952. PubMed ID: 34731763
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives.
    Bakr RB; Mehany ABM; Abdellatif KRA
    Anticancer Agents Med Chem; 2017; 17(10):1389-1400. PubMed ID: 28270084
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of New Pyrazolopyridine, Furopyridine, and Pyridine Derivatives as CDK2 Inhibitors: Design, Synthesis, Docking Studies, and Anti-Proliferative Activity.
    Abdel-Rahman AA; Shaban AKF; Nassar IF; El-Kady DS; Ismail NSM; Mahmoud SF; Awad HM; El-Sayed WA
    Molecules; 2021 Jun; 26(13):. PubMed ID: 34206976
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation.
    Zhai M; Liu S; Gao M; Wang L; Sun J; Du J; Guan Q; Bao K; Zuo D; Wu Y; Zhang W
    Eur J Med Chem; 2019 Apr; 168():426-435. PubMed ID: 30831410
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of intrinsic apoptosis pathway in colon cancer HCT-116 cells by novel 2-substituted-5,6,7,8-tetrahydronaphthalene derivatives.
    Gamal-Eldeen AM; Hamdy NA; Abdel-Aziz HA; El-Hussieny EA; Fakhr IM
    Eur J Med Chem; 2014 Apr; 77():323-33. PubMed ID: 24657569
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, cytotoxicity, antimicrobial and anti-biofilm activities of novel pyrazolo[3,4-b]pyridine and pyrimidine functionalized 1,2,3-triazole derivatives.
    Nagender P; Malla Reddy G; Naresh Kumar R; Poornachandra Y; Ganesh Kumar C; Narsaiah B
    Bioorg Med Chem Lett; 2014 Jul; 24(13):2905-8. PubMed ID: 24835633
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and anti-tumor activities of some new pyridines and pyrazolo[1,5-a]pyrimidines.
    Ahmed OM; Mohamed MA; Ahmed RR; Ahmed SA
    Eur J Med Chem; 2009 Sep; 44(9):3519-23. PubMed ID: 19398146
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, Characterization, Antimicrobial Activity and Anticancer of Some New Pyrazolo[1,5-a]pyrimidines and Pyrazolo[5,1-c]1,2,4-triazines.
    Hosny MA; Zaki YH; Mokbel WA; Abdelhamid AO
    Med Chem; 2020; 16(6):750-760. PubMed ID: 31218963
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of novel pyrazolo[3,4-b]pyridines as cis-restricted combretastatin A-4 analogues.
    Jian XE; Yang F; Jiang CS; You WW; Zhao PL
    Bioorg Med Chem Lett; 2020 Apr; 30(8):127025. PubMed ID: 32063430
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and in-vitro anti-proliferative evaluation of some pyrazolo[1,5-a]pyrimidines as novel larotrectinib analogs.
    Attia MH; Elrazaz EZ; El-Emam SZ; Taher AT; Abdel-Aziz HA; Abouzid KAM
    Bioorg Chem; 2020 Jan; 94():103458. PubMed ID: 31785854
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of novel 1H-Pyrazolo[3,4-b]pyridine derivatives as DYRK 1A/1B inhibitors.
    Park A; Hwang J; Lee JY; Heo EJ; Na YJ; Kang S; Jeong KS; Kim KY; Shin SJ; Lee H
    Bioorg Med Chem Lett; 2021 Sep; 47():128226. PubMed ID: 34182093
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, antitumor evaluation and microarray study of some new pyrazolo[3,4-d][1,2,3]triazine derivatives.
    Nasr T; Bondock S; Youns M; Fayad W; Zaghary W
    Eur J Med Chem; 2017 Dec; 141():603-614. PubMed ID: 29107422
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanistic selectivity investigation and 2D-QSAR study of some new antiproliferative pyrazoles and pyrazolopyridines as potential CDK2 inhibitors.
    Hassan GS; Georgey HH; Mohammed EZ; George RF; Mahmoud WR; Omar FA
    Eur J Med Chem; 2021 Jun; 218():113389. PubMed ID: 33784602
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A convenient synthesis and molecular modeling study of novel pyrazolo[3,4-d]pyrimidine and pyrazole derivatives as anti-tumor agents.
    Nassar IF; Atta-Allah SR; Elgazwy AS
    J Enzyme Inhib Med Chem; 2015 Jun; 30(3):396-405. PubMed ID: 25068728
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and cytotoxicity studies of novel pyrazolo[1, 5-a]pyridine derivatives.
    Ravi C; Qayum A; Chandra Mohan D; Singh SK; Adimurthy S
    Eur J Med Chem; 2017 Jan; 126():277-285. PubMed ID: 27889631
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.