BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 29368147)

  • 1. Cytochrome b
    Reed L; Mrizova I; Barta F; Indra R; Moserova M; Kopka K; Schmeiser HH; Wolf CR; Henderson CJ; Stiborova M; Phillips DH; Arlt VM
    Arch Toxicol; 2018 Apr; 92(4):1625-1638. PubMed ID: 29368147
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Application of hepatic cytochrome b
    Reed L; Indra R; Mrizova I; Moserova M; Schmeiser HH; Wolf CR; Henderson CJ; Stiborova M; Phillips DH; Arlt VM
    Toxicol Appl Pharmacol; 2019 Mar; 366():64-74. PubMed ID: 30685480
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Exposure to benzo[a]pyrene of Hepatic Cytochrome P450 Reductase Null (HRN) and P450 Reductase Conditional Null (RCN) mice: Detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and 32P-postlabelling.
    Arlt VM; Poirier MC; Sykes SE; John K; Moserova M; Stiborova M; Wolf CR; Henderson CJ; Phillips DH
    Toxicol Lett; 2012 Sep; 213(2):160-6. PubMed ID: 22759596
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice.
    Arlt VM; Stiborová M; Henderson CJ; Thiemann M; Frei E; Aimová D; Singh R; Gamboa da Costa G; Schmitz OJ; Farmer PB; Wolf CR; Phillips DH
    Carcinogenesis; 2008 Mar; 29(3):656-65. PubMed ID: 18204078
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions.
    Stiborová M; Moserová M; Černá V; Indra R; Dračínský M; Šulc M; Henderson CJ; Wolf CR; Schmeiser HH; Phillips DH; Frei E; Arlt VM
    Toxicology; 2014 Apr; 318():1-12. PubMed ID: 24530354
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase.
    Reed L; Jarvis IWH; Phillips DH; Arlt VM
    Mutat Res Genet Toxicol Environ Mutagen; 2020 Apr; 852():503162. PubMed ID: 32265041
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene.
    Stiborová M; Indra R; Moserová M; Frei E; Schmeiser HH; Kopka K; Phillips DH; Arlt VM
    Chem Res Toxicol; 2016 Aug; 29(8):1325-34. PubMed ID: 27404282
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deletion of cytochrome P450 oxidoreductase enhances metabolism and DNA adduct formation of benzo[a]pyrene in Hepa1c1c7 cells.
    Reed L; Jarvis IWH; Phillips DH; Arlt VM
    Mutagenesis; 2019 Dec; 34(5-6):413-420. PubMed ID: 31612222
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA adduct formation in P450 reductase conditional null mice.
    Arlt VM; Singh R; Stiborová M; Gamboa da Costa G; Frei E; Evans JD; Farmer PB; Wolf CR; Henderson CJ; Phillips DH
    Drug Metab Dispos; 2011 Dec; 39(12):2169-73. PubMed ID: 21940903
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: studies with the hepatic NADPH:cytochrome P450 reductase null mouse.
    Stiborová M; Arlt VM; Henderson CJ; Wolf CR; Kotrbová V; Moserová M; Hudecek J; Phillips DH; Frei E
    Toxicol Appl Pharmacol; 2008 Feb; 226(3):318-27. PubMed ID: 17976674
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evidence that cytochrome b5 and cytochrome b5 reductase can act as sole electron donors to the hepatic cytochrome P450 system.
    Henderson CJ; McLaughlin LA; Wolf CR
    Mol Pharmacol; 2013 Jun; 83(6):1209-17. PubMed ID: 23530090
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation and detoxification metabolism of urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone by rat and mouse hepatic microsomes.
    Stiborova M; Cechova T; Borek-Dohalska L; Moserova M; Frei E; Schmeiser HH; Paca J; Arlt VM
    Neuro Endocrinol Lett; 2012; 33 Suppl 3():8-15. PubMed ID: 23353838
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[
    Stiborová M; Indra R; Moserová M; Šulc M; Hodek P; Frei E; Schmeiser HH; Arlt VM
    Monatsh Chem; 2016; 147():847-855. PubMed ID: 27110038
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The relationship between DNA adduct formation by benzo[a]pyrene and expression of its activation enzyme cytochrome P450 1A1 in rat.
    Hodek P; Koblihová J; Kizek R; Frei E; Arlt VM; Stiborová M
    Environ Toxicol Pharmacol; 2013 Nov; 36(3):989-96. PubMed ID: 24095716
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model.
    Levová K; Moserová M; Kotrbová V; Sulc M; Henderson CJ; Wolf CR; Phillips DH; Frei E; Schmeiser HH; Mares J; Arlt VM; Stiborová M
    Toxicol Sci; 2011 May; 121(1):43-56. PubMed ID: 21362632
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Detoxification of benzo[a]pyrene primarily depends on cytochrome P450, while bioactivation involves additional oxidoreductases including 5-lipoxygenase, cyclooxygenase, and aldo-keto reductase in the liver.
    Wang L; Xu W; Ma L; Zhang S; Zhang K; Ye P; Xing G; Zhang X; Cao Y; Xi J; Gu J; Luan Y
    J Biochem Mol Toxicol; 2017 Jul; 31(7):. PubMed ID: 28111842
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The effect of benzo[a]pyrene on metabolic activation of anticancer drug ellipticine in mice.
    Stiborova M; Cerna V; Moserova M; Arlt VM; Frei E
    Neuro Endocrinol Lett; 2013; 34 Suppl 2():43-54. PubMed ID: 24362092
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice.
    Krais AM; Speksnijder EN; Melis JP; Indra R; Moserova M; Godschalk RW; van Schooten FJ; Seidel A; Kopka K; Schmeiser HH; Stiborova M; Phillips DH; Luijten M; Arlt VM
    Arch Toxicol; 2016 Apr; 90(4):839-51. PubMed ID: 25995008
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase.
    Arlt VM; Stiborova M; Hewer A; Schmeiser HH; Phillips DH
    Cancer Res; 2003 Jun; 63(11):2752-61. PubMed ID: 12782579
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolism of and DNA adduct formation by benzo[alpha]pyrene in human skin epithelial cells in vitro pretreated with cytochrome P450 modulators.
    Lehman TA; Kurian P; Milo GE
    Cancer Biochem Biophys; 1989 Oct; 10(4):345-52. PubMed ID: 2515917
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.