189 related articles for article (PubMed ID: 29368982)
1. RAS-related GTPases DIRAS1 and DIRAS2 induce autophagic cancer cell death and are required for autophagy in murine ovarian cancer cells.
Sutton MN; Yang H; Huang GY; Fu C; Pontikos M; Wang Y; Mao W; Pang L; Yang M; Liu J; Parker-Thornburg J; Lu Z; Bast RC
Autophagy; 2018; 14(4):637-653. PubMed ID: 29368982
[TBL] [Abstract][Full Text] [Related]
2. The role of vascular endothelial growth factor, interleukin 8, and insulinlike growth factor in sustaining autophagic DIRAS3-induced dormant ovarian cancer xenografts.
Mao W; Peters HL; Sutton MN; Orozco AF; Pang L; Yang H; Lu Z; Bast RC
Cancer; 2019 Apr; 125(8):1267-1280. PubMed ID: 30620384
[TBL] [Abstract][Full Text] [Related]
3. ARHI (DIRAS3) induces autophagy in ovarian cancer cells by downregulating the epidermal growth factor receptor, inhibiting PI3K and Ras/MAP signaling and activating the FOXo3a-mediated induction of Rab7.
Lu Z; Yang H; Sutton MN; Yang M; Clarke CH; Liao WS; Bast RC
Cell Death Differ; 2014 Aug; 21(8):1275-89. PubMed ID: 24769729
[TBL] [Abstract][Full Text] [Related]
4. The Tumor-suppressive Small GTPase DiRas1 Binds the Noncanonical Guanine Nucleotide Exchange Factor SmgGDS and Antagonizes SmgGDS Interactions with Oncogenic Small GTPases.
Bergom C; Hauser AD; Rymaszewski A; Gonyo P; Prokop JW; Jennings BC; Lawton AJ; Frei A; Lorimer EL; Aguilera-Barrantes I; Mackinnon AC; Noon K; Fierke CA; Williams CL
J Biol Chem; 2016 Mar; 291(12):6534-45. PubMed ID: 26814130
[TBL] [Abstract][Full Text] [Related]
5. The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells.
Lu Z; Luo RZ; Lu Y; Zhang X; Yu Q; Khare S; Kondo S; Kondo Y; Yu Y; Mills GB; Liao WS; Bast RC
J Clin Invest; 2008 Dec; 118(12):3917-29. PubMed ID: 19033662
[TBL] [Abstract][Full Text] [Related]
6. DIRAS3 regulates the autophagosome initiation complex in dormant ovarian cancer cells.
Lu Z; Baquero MT; Yang H; Yang M; Reger AS; Kim C; Levine DA; Clarke CH; Liao WS; Bast RC
Autophagy; 2014 Jun; 10(6):1071-92. PubMed ID: 24879154
[TBL] [Abstract][Full Text] [Related]
7. DIRAS3: An Imprinted Tumor Suppressor Gene that Regulates RAS and PI3K-driven Cancer Growth, Motility, Autophagy, and Tumor Dormancy.
Bildik G; Liang X; Sutton MN; Bast RC; Lu Z
Mol Cancer Ther; 2022 Jan; 21(1):25-37. PubMed ID: 34667114
[TBL] [Abstract][Full Text] [Related]
8. ARHI (DIRAS3)-mediated autophagy-associated cell death enhances chemosensitivity to cisplatin in ovarian cancer cell lines and xenografts.
Washington MN; Suh G; Orozco AF; Sutton MN; Yang H; Wang Y; Mao W; Millward S; Ornelas A; Atkinson N; Liao W; Bast RC; Lu Z
Cell Death Dis; 2015 Aug; 6(8):e1836. PubMed ID: 26247722
[TBL] [Abstract][Full Text] [Related]
9. DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1.
Sutton MN; Huang GY; Liang X; Sharma R; Reger AS; Mao W; Pang L; Rask PJ; Lee K; Gray JP; Hurwitz AM; Palzkill T; Millward SW; Kim C; Lu Z; Bast RC
Cancers (Basel); 2019 Apr; 11(4):. PubMed ID: 31003488
[TBL] [Abstract][Full Text] [Related]
10. Biochemistry and biology of ARHI (DIRAS3), an imprinted tumor suppressor gene whose expression is lost in ovarian and breast cancers.
Yu Y; Luo R; Lu Z; Wei Feng W; Badgwell D; Issa JP; Rosen DG; Liu J; Bast RC
Methods Enzymol; 2006; 407():455-68. PubMed ID: 16757345
[TBL] [Abstract][Full Text] [Related]
11. Induction of autophagy by ARHI (DIRAS3) alters fundamental metabolic pathways in ovarian cancer models.
Ornelas A; McCullough CR; Lu Z; Zacharias NM; Kelderhouse LE; Gray J; Yang H; Engel BJ; Wang Y; Mao W; Sutton MN; Bhattacharya PK; Bast RC; Millward SW
BMC Cancer; 2016 Oct; 16(1):824. PubMed ID: 27784287
[TBL] [Abstract][Full Text] [Related]
12. The tumor suppressor gene ARHI (DIRAS3) inhibits ovarian cancer cell migration through multiple mechanisms.
Lu Z; Bast RC
Cell Adh Migr; 2013; 7(2):232-6. PubMed ID: 23357870
[TBL] [Abstract][Full Text] [Related]
13. The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways.
Badgwell DB; Lu Z; Le K; Gao F; Yang M; Suh GK; Bao JJ; Das P; Andreeff M; Chen W; Yu Y; Ahmed AA; S-L Liao W; Bast RC
Oncogene; 2012 Jan; 31(1):68-79. PubMed ID: 21643014
[TBL] [Abstract][Full Text] [Related]
14. DIRAS3 induces autophagy and enhances sensitivity to anti-autophagic therapy in KRAS-driven pancreatic and ovarian carcinomas.
Bildik G; Gray JP; Mao W; Yang H; Ozyurt R; Orellana VR; De Wever O; Carey MS; Bast RC; Lu Z
Autophagy; 2024 Mar; 20(3):675-691. PubMed ID: 38169324
[TBL] [Abstract][Full Text] [Related]
15. Amino Acid Deprivation-Induced Autophagy Requires Upregulation of DIRAS3 through Reduction of E2F1 and E2F4 Transcriptional Repression.
Sutton MN; Huang GY; Zhou J; Mao W; Langley R; Lu Z; Bast RC
Cancers (Basel); 2019 Apr; 11(5):. PubMed ID: 31052266
[TBL] [Abstract][Full Text] [Related]
16. Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel.
Zou CF; Jia L; Jin H; Yao M; Zhao N; Huan J; Lu Z; Bast RC; Feng Y; Yu Y
BMC Cancer; 2011 Jan; 11():22. PubMed ID: 21244707
[TBL] [Abstract][Full Text] [Related]
17. Expression and epigenetic regulation of angiogenesis-related factors during dormancy and recurrent growth of ovarian carcinoma.
Lyu T; Jia N; Wang J; Yan X; Yu Y; Lu Z; Bast RC; Hua K; Feng W
Epigenetics; 2013 Dec; 8(12):1330-46. PubMed ID: 24135786
[TBL] [Abstract][Full Text] [Related]
18. The tumour suppressor DiRas3 interacts with C-RAF and downregulates MEK activity to restrict cell migration.
Klingauf M; Beck M; Berge U; Turgay Y; Heinzer S; Horvath P; Kroschewski R
Biol Cell; 2013 Feb; 105(2):91-107. PubMed ID: 23157514
[TBL] [Abstract][Full Text] [Related]
19. ARHI is a Ras-related small G-protein with a novel N-terminal extension that inhibits growth of ovarian and breast cancers.
Luo RZ; Fang X; Marquez R; Liu SY; Mills GB; Liao WS; Yu Y; Bast RC
Oncogene; 2003 May; 22(19):2897-909. PubMed ID: 12771940
[TBL] [Abstract][Full Text] [Related]
20. Diverse Ras-related GTPase DIRAS2, downregulated by PSMD2 in a proteasome-mediated way, inhibits colorectal cancer proliferation by blocking NF-κB signaling.
Ying K; Wang C; Liu S; Kuang Y; Tao Q; Hu X
Int J Biol Sci; 2022; 18(3):1039-1050. PubMed ID: 35173535
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]