314 related articles for article (PubMed ID: 29369823)
1. iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.
Qing X; Chinenov Y; Redecha P; Madaio M; Roelofs JJ; Farber G; Issuree PD; Donlin L; Mcllwain DR; Mak TW; Blobel CP; Salmon JE
J Clin Invest; 2018 Apr; 128(4):1397-1412. PubMed ID: 29369823
[TBL] [Abstract][Full Text] [Related]
2. The xenoestrogens biphenol-A and nonylphenol differentially regulate metalloprotease-mediated shedding of EGFR ligands.
Urriola-Muñoz P; Li X; Maretzky T; McIlwain DR; Mak TW; Reyes JG; Blobel CP; Moreno RD
J Cell Physiol; 2018 Mar; 233(3):2247-2256. PubMed ID: 28703301
[TBL] [Abstract][Full Text] [Related]
3. Activated iRhom2 drives prolonged PM
Xu MX; Qin YT; Ge CX; Gu TT; Lou DS; Li Q; Hu LF; Li YY; Yang WW; Tan J
Nanotoxicology; 2018 Nov; 12(9):1045-1067. PubMed ID: 30257117
[TBL] [Abstract][Full Text] [Related]
4. ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).
Weskamp G; Tüshaus J; Li D; Feederle R; Maretzky T; Swendemann S; Falck-Pedersen E; McIlwain DR; Mak TW; Salmon JE; Lichtenthaler SF; Blobel CP
J Biol Chem; 2020 Mar; 295(13):4350-4358. PubMed ID: 32060096
[TBL] [Abstract][Full Text] [Related]
5. Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.
Haxaire C; Hakobyan N; Pannellini T; Carballo C; McIlwain D; Mak TW; Rodeo S; Acharya S; Li D; Szymonifka J; Song X; Monette S; Srivastava A; Salmon JE; Blobel CP
Blood; 2018 Sep; 132(10):1064-1074. PubMed ID: 29776906
[TBL] [Abstract][Full Text] [Related]
6. iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Li X; Maretzky T; Weskamp G; Monette S; Qing X; Issuree PD; Crawford HC; McIlwain DR; Mak TW; Salmon JE; Blobel CP
Proc Natl Acad Sci U S A; 2015 May; 112(19):6080-5. PubMed ID: 25918388
[TBL] [Abstract][Full Text] [Related]
7. iRhom2: An Emerging Adaptor Regulating Immunity and Disease.
Al-Salihi MA; Lang PA
Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32911849
[TBL] [Abstract][Full Text] [Related]
8. iRhom2 loss alleviates renal injury in long-term PM2.5-exposed mice by suppression of inflammation and oxidative stress.
Chenxu G; Minxuan X; Yuting Q; Tingting G; Jinxiao L; Mingxing W; Sujun W; Yongjie M; Deshuai L; Qiang L; Linfeng H; Jun T
Redox Biol; 2018 Oct; 19():147-157. PubMed ID: 30165303
[TBL] [Abstract][Full Text] [Related]
9. iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.
Maretzky T; McIlwain DR; Issuree PD; Li X; Malapeira J; Amin S; Lang PA; Mak TW; Blobel CP
Proc Natl Acad Sci U S A; 2013 Jul; 110(28):11433-8. PubMed ID: 23801765
[TBL] [Abstract][Full Text] [Related]
10. The Role of iRhom2 in Metabolic and Cardiovascular-Related Disorders.
Geesala R; Issuree PD; Maretzky T
Front Cardiovasc Med; 2020; 7():612808. PubMed ID: 33330676
[TBL] [Abstract][Full Text] [Related]
11. Specific endothelial heparin-binding EGF-like growth factor deletion ameliorates renal injury induced by chronic angiotensin II infusion.
Zeng F; Kloepfer LA; Finney C; Diedrich A; Harris RC
Am J Physiol Renal Physiol; 2016 Oct; 311(4):F695-F707. PubMed ID: 27226110
[TBL] [Abstract][Full Text] [Related]
12. Arsenic Attenuates Heparin-Binding EGF-Like Growth Factor/EGFR Signaling That Promotes Matrix Metalloprotease 9-Dependent Astrocyte Damage in the Developing Rat Brain.
Kushwaha R; Mishra J; Tripathi S; Raza W; Mandrah K; Roy SK; Bandyopadhyay S
Toxicol Sci; 2018 Apr; 162(2):406-428. PubMed ID: 29228391
[TBL] [Abstract][Full Text] [Related]
13. iRhom2 deficiency relieves TNF-α associated hepatic dyslipidemia in long-term PM2.5-exposed mice.
Ge CX; Qin YT; Lou DS; Li Q; Li YY; Wang ZM; Yang WW; Wang M; Liu N; Wang Z; Zhang PX; Tu YY; Tan J; Xu MX
Biochem Biophys Res Commun; 2017 Dec; 493(4):1402-1409. PubMed ID: 28965953
[TBL] [Abstract][Full Text] [Related]
14. iRhom2 inhibits bile duct obstruction-induced liver fibrosis.
Sundaram B; Behnke K; Belancic A; Al-Salihi MA; Thabet Y; Polz R; Pellegrino R; Zhuang Y; Shinde PV; Xu HC; Vasilevska J; Longerich T; Herebian D; Mayatepek E; Bock HH; May P; Kordes C; Aghaeepour N; Mak TW; Keitel V; Häussinger D; Scheller J; Pandyra AA; Lang KS; Lang PA
Sci Signal; 2019 Oct; 12(605):. PubMed ID: 31662486
[TBL] [Abstract][Full Text] [Related]
15. Mechanistic insight on the role of iRhom2-TNF-α-BAFF signaling pathway in various autoimmune disorders.
Dwivedi SD; Shukla R; Yadav K; Rathor LS; Singh D; Singh MR
Adv Biol Regul; 2024 May; 92():101011. PubMed ID: 38151421
[TBL] [Abstract][Full Text] [Related]
16. Both Autocrine Signaling and Paracrine Signaling of HB-EGF Enhance Ocular Neovascularization.
Inoue Y; Shimazawa M; Nakamura S; Takata S; Hashimoto Y; Izawa H; Masuda T; Tsuruma K; Sakaue T; Nakayama H; Higashiyama S; Hara H
Arterioscler Thromb Vasc Biol; 2018 Jan; 38(1):174-185. PubMed ID: 29191924
[TBL] [Abstract][Full Text] [Related]
17. Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.
Hosur V; Johnson KR; Burzenski LM; Stearns TM; Maser RS; Shultz LD
Proc Natl Acad Sci U S A; 2014 May; 111(21):E2200-9. PubMed ID: 24825892
[TBL] [Abstract][Full Text] [Related]
18. Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.
Tang B; Li X; Maretzky T; Perez-Aguilar JM; McIlwain D; Xie Y; Zheng Y; Mak TW; Weinstein H; Blobel CP
FASEB J; 2020 Apr; 34(4):4956-4969. PubMed ID: 32103528
[TBL] [Abstract][Full Text] [Related]
19. Inactive Rhomboid Protein 2 Mediates Intestinal Inflammation by Releasing Tumor Necrosis Factor-α.
Kim JH; Hwang SW; Koh J; Chun J; Lee C; Im JP; Kim JS
Inflamm Bowel Dis; 2020 Jan; 26(2):242-253. PubMed ID: 31586441
[TBL] [Abstract][Full Text] [Related]
20. Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE.
Adrain C; Zettl M; Christova Y; Taylor N; Freeman M
Science; 2012 Jan; 335(6065):225-8. PubMed ID: 22246777
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]