462 related articles for article (PubMed ID: 29377149)
1. Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes.
Arunagiri A; Haataja L; Cunningham CN; Shrestha N; Tsai B; Qi L; Liu M; Arvan P
Ann N Y Acad Sci; 2018 Apr; 1418(1):5-19. PubMed ID: 29377149
[TBL] [Abstract][Full Text] [Related]
2. Disulfide Mispairing During Proinsulin Folding in the Endoplasmic Reticulum.
Haataja L; Manickam N; Soliman A; Tsai B; Liu M; Arvan P
Diabetes; 2016 Apr; 65(4):1050-60. PubMed ID: 26822090
[TBL] [Abstract][Full Text] [Related]
3. Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.
Sun J; Cui J; He Q; Chen Z; Arvan P; Liu M
Mol Aspects Med; 2015 Apr; 42():105-18. PubMed ID: 25579745
[TBL] [Abstract][Full Text] [Related]
4. Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress.
Wright J; Birk J; Haataja L; Liu M; Ramming T; Weiss MA; Appenzeller-Herzog C; Arvan P
J Biol Chem; 2013 Oct; 288(43):31010-8. PubMed ID: 24022479
[TBL] [Abstract][Full Text] [Related]
5. Distinct states of proinsulin misfolding in MIDY.
Haataja L; Arunagiri A; Hassan A; Regan K; Tsai B; Dhayalan B; Weiss MA; Liu M; Arvan P
Cell Mol Life Sci; 2021 Aug; 78(16):6017-6031. PubMed ID: 34245311
[TBL] [Abstract][Full Text] [Related]
6. Proinsulin entry and transit through the endoplasmic reticulum in pancreatic beta cells.
Liu M; Wright J; Guo H; Xiong Y; Arvan P
Vitam Horm; 2014; 95():35-62. PubMed ID: 24559913
[TBL] [Abstract][Full Text] [Related]
7. Mutant INS-gene induced diabetes of youth: proinsulin cysteine residues impose dominant-negative inhibition on wild-type proinsulin transport.
Liu M; Haataja L; Wright J; Wickramasinghe NP; Hua QX; Phillips NF; Barbetti F; Weiss MA; Arvan P
PLoS One; 2010 Oct; 5(10):e13333. PubMed ID: 20948967
[TBL] [Abstract][Full Text] [Related]
8. Biological behaviors of mutant proinsulin contribute to the phenotypic spectrum of diabetes associated with insulin gene mutations.
Wang H; Saint-Martin C; Xu J; Ding L; Wang R; Feng W; Liu M; Shu H; Fan Z; Haataja L; Arvan P; Bellanné-Chantelot C; Cui J; Huang Y
Mol Cell Endocrinol; 2020 Dec; 518():111025. PubMed ID: 32916194
[TBL] [Abstract][Full Text] [Related]
9. Biosynthesis, structure, and folding of the insulin precursor protein.
Liu M; Weiss MA; Arunagiri A; Yong J; Rege N; Sun J; Haataja L; Kaufman RJ; Arvan P
Diabetes Obes Metab; 2018 Sep; 20 Suppl 2(Suppl 2):28-50. PubMed ID: 30230185
[TBL] [Abstract][Full Text] [Related]
10. Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth.
Liu M; Hodish I; Haataja L; Lara-Lemus R; Rajpal G; Wright J; Arvan P
Trends Endocrinol Metab; 2010 Nov; 21(11):652-9. PubMed ID: 20724178
[TBL] [Abstract][Full Text] [Related]
11. Defective endoplasmic reticulum export causes proinsulin misfolding in pancreatic β cells.
Zhu R; Li X; Xu J; Barrabi C; Kekulandara D; Woods J; Chen X; Liu M
Mol Cell Endocrinol; 2019 Aug; 493():110470. PubMed ID: 31158417
[TBL] [Abstract][Full Text] [Related]
12. Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
Arunagiri A; Alam M; Haataja L; Draz H; Alasad B; Samy P; Sadique N; Tong Y; Cai Y; Shakeri H; Fantuzzi F; Ibrahim H; Jang I; Sidarala V; Soleimanpour SA; Satin LS; Otonkoski T; Cnop M; Itkin-Ansari P; Kaufman RJ; Liu M; Arvan P
Protein Sci; 2024 Apr; 33(4):e4949. PubMed ID: 38511500
[TBL] [Abstract][Full Text] [Related]
13. Proinsulin misfolding is an early event in the progression to type 2 diabetes.
Arunagiri A; Haataja L; Pottekat A; Pamenan F; Kim S; Zeltser LM; Paton AW; Paton JC; Tsai B; Itkin-Ansari P; Kaufman RJ; Liu M; Arvan P
Elife; 2019 Jun; 8():. PubMed ID: 31184302
[TBL] [Abstract][Full Text] [Related]
14. INS-gene mutations: from genetics and beta cell biology to clinical disease.
Liu M; Sun J; Cui J; Chen W; Guo H; Barbetti F; Arvan P
Mol Aspects Med; 2015 Apr; 42():3-18. PubMed ID: 25542748
[TBL] [Abstract][Full Text] [Related]
15. Chaperone-Driven Degradation of a Misfolded Proinsulin Mutant in Parallel With Restoration of Wild-Type Insulin Secretion.
Cunningham CN; He K; Arunagiri A; Paton AW; Paton JC; Arvan P; Tsai B
Diabetes; 2017 Mar; 66(3):741-753. PubMed ID: 28028074
[TBL] [Abstract][Full Text] [Related]
16. Misfolded proinsulin impairs processing of precursor of insulin receptor and insulin signaling in β cells.
Liu S; Li X; Yang J; Zhu R; Fan Z; Xu X; Feng W; Cui J; Sun J; Liu M
FASEB J; 2019 Oct; 33(10):11338-11348. PubMed ID: 31311313
[TBL] [Abstract][Full Text] [Related]
17. PDI reductase acts on Akita mutant proinsulin to initiate retrotranslocation along the Hrd1/Sel1L-p97 axis.
He K; Cunningham CN; Manickam N; Liu M; Arvan P; Tsai B
Mol Biol Cell; 2015 Oct; 26(19):3413-23. PubMed ID: 26269577
[TBL] [Abstract][Full Text] [Related]
18. Diabetes-Associated Mutations in Proinsulin Provide a "Molecular Rheostat" of Nascent Foldability.
Dhayalan B; Weiss MA
Curr Diab Rep; 2022 Feb; 22(2):85-94. PubMed ID: 35119630
[TBL] [Abstract][Full Text] [Related]
19. SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells.
Tiwari A; Schuiki I; Zhang L; Allister EM; Wheeler MB; Volchuk A
J Cell Sci; 2013 May; 126(Pt 9):1962-8. PubMed ID: 23444373
[TBL] [Abstract][Full Text] [Related]
20. Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes.
Balboa D; Saarimäki-Vire J; Borshagovski D; Survila M; Lindholm P; Galli E; Eurola S; Ustinov J; Grym H; Huopio H; Partanen J; Wartiovaara K; Otonkoski T
Elife; 2018 Nov; 7():. PubMed ID: 30412052
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
