These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 29381062)

  • 1. Improved Total Synthesis of Tubulysins and Design, Synthesis, and Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for Antibody-Drug Conjugates.
    Nicolaou KC; Erande RD; Yin J; Vourloumis D; Aujay M; Sandoval J; Munneke S; Gavrilyuk J
    J Am Chem Soc; 2018 Mar; 140(10):3690-3711. PubMed ID: 29381062
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Total Synthesis and Biological Evaluation of Natural and Designed Tubulysins.
    Nicolaou KC; Yin J; Mandal D; Erande RD; Klahn P; Jin M; Aujay M; Sandoval J; Gavrilyuk J; Vourloumis D
    J Am Chem Soc; 2016 Feb; 138(5):1698-708. PubMed ID: 26829208
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Total synthesis of tubulysin U and its C-4 epimer.
    Yang XD; Dong CM; Chen J; Ding YH; Liu Q; Ma XY; Zhang Q; Chen Y
    Chem Asian J; 2013 Jun; 8(6):1213-22. PubMed ID: 23576385
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Total synthesis and biological evaluation of tubulysin U, tubulysin V, and their analogues.
    Balasubramanian R; Raghavan B; Begaye A; Sackett DL; Fecik RA
    J Med Chem; 2009 Jan; 52(2):238-40. PubMed ID: 19102699
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Total syntheses of tubulysins.
    Shibue T; Hirai T; Okamoto I; Morita N; Masu H; Azumaya I; Tamura O
    Chemistry; 2010 Oct; 16(38):11678-88. PubMed ID: 20734394
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural recognition of tubulysin B derivatives by multidrug resistance efflux transporters in human cancer cells.
    Stark M; Assaraf YG
    Oncotarget; 2017 Jul; 8(30):49973-49987. PubMed ID: 28637003
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationships of tubulysin analogues.
    Courter JR; Hamilton JZ; Hendrick NR; Zaval M; Waight AB; Lyon RP; Senter PD; Jeffrey SC; Burke PJ
    Bioorg Med Chem Lett; 2020 Jul; 30(14):127241. PubMed ID: 32527543
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Improved Access to Potent Anticancer Tubulysins and Linker-Functionalized Payloads Via an All-On-Resin Strategy.
    Ricardo MG; Llanes D; Rennert R; Jänicke P; Rivera DG; Wessjohann LA
    Chemistry; 2024 Jul; 30(42):e202401943. PubMed ID: 38771268
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and structure-activity relationship studies of novel tubulysin U analogues--effect on cytotoxicity of structural variations in the tubuvaline fragment.
    Shankar SP; Jagodzinska M; Malpezzi L; Lazzari P; Manca I; Greig IR; Sani M; Zanda M
    Org Biomol Chem; 2013 Apr; 11(14):2273-87. PubMed ID: 23411563
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anticancer effects of a specific mixture of nutrients in the multidrug-resistant human uterine sarcoma MES-SA/Dx5 and the drug-sensitive MES-SA cell lines.
    Roomi MW; Kalinovsky T; Roomi NW; Rath M; Niedzwiecki A
    Oncol Rep; 2012 Jan; 27(1):17-27. PubMed ID: 21947138
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Introducing Glycolinkers for the Functionalization of Cytotoxic Drugs and Applications in Antibody-Drug Conjugation Chemistry.
    Ekholm FS; Pynnönen H; Vilkman A; Pitkänen V; Helin J; Saarinen J; Satomaa T
    ChemMedChem; 2016 Nov; 11(22):2501-2505. PubMed ID: 27786414
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Recent Developments of ADCs with the Tubulysins as the Payloads.
    Xiangrong X; Yao L; Yao A
    Mini Rev Med Chem; 2023; 23(18):1797-1805. PubMed ID: 36825713
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and antitumor activity evaluation of pretubulysin analogs.
    Xu X; Fan M; Qi J; Yao L
    Chem Biol Drug Des; 2021 Sep; 98(3):341-351. PubMed ID: 33930251
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-Cytotoxicity Relationships of Analogues of N
    Toader D; Wang F; Gingipalli L; Vasbinder M; Roth M; Mao S; Block M; Harper J; Thota S; Su M; Ma J; Bedian V; Kamal A
    J Med Chem; 2016 Dec; 59(23):10781-10787. PubMed ID: 27809515
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of novel amino-substituted xanthenones and benzo[b]xanthenones: evaluation of their antiproliferative activity and their ability to overcome multidrug resistance toward MES-SA/D x 5 cells.
    Kostakis IK; Pouli N; Marakos P; Skaltsounis AL; Pratsinis H; Kletsas D
    Bioorg Med Chem; 2006 May; 14(9):2910-34. PubMed ID: 16376546
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and Biological Evaluation of a Carbamate-Containing Tubulysin Antibody-Drug Conjugate.
    Cheng H; Cong Q; Dervin D; Stevens A; Vemuri K; Huber M; Juliano J; Cuison S; Sung J; Passmore D; Chong C; Greenbaum M; Kwok E; Jiang J; Pan C; Rao-Naik C; Rangan V; Kempe T; Tatum A; Deshpande S; Cardarelli P; Vite G; Gangwar S
    Bioconjug Chem; 2020 Oct; 31(10):2350-2361. PubMed ID: 32881482
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pretubulysin, a potent and chemically accessible tubulysin precursor from Angiococcus disciformis.
    Ullrich A; Chai Y; Pistorius D; Elnakady YA; Herrmann JE; Weissman KJ; Kazmaier U; Müller R
    Angew Chem Int Ed Engl; 2009; 48(24):4422-5. PubMed ID: 19431172
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Total Synthesis in Search of Potent Antibody-Drug Conjugate Payloads. From the Fundamentals to the Translational.
    Nicolaou KC; Rigol S
    Acc Chem Res; 2019 Jan; 52(1):127-139. PubMed ID: 30575399
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Simplified pretubulysin derivatives and their biological effects on cancer cells.
    Kubisch R; von Gamm M; Braig S; Ullrich A; Burkhart JL; Colling L; Hermann J; Scherer O; Müller R; Werz O; Kazmaier U; Vollmar AM
    J Nat Prod; 2014 Mar; 77(3):536-42. PubMed ID: 24437936
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads.
    Leverett CA; Sukuru SC; Vetelino BC; Musto S; Parris K; Pandit J; Loganzo F; Varghese AH; Bai G; Liu B; Liu D; Hudson S; Doppalapudi VR; Stock J; O'Donnell CJ; Subramanyam C
    ACS Med Chem Lett; 2016 Nov; 7(11):999-1004. PubMed ID: 27882198
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.