238 related articles for article (PubMed ID: 29382728)
1. The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53.
Madan E; Parker TM; Bauer MR; Dhiman A; Pelham CJ; Nagane M; Kuppusamy ML; Holmes M; Holmes TR; Shaik K; Shee K; Kiparoidze S; Smith SD; Park YA; Gomm JJ; Jones LJ; Tomás AR; Cunha AC; Selvendiran K; Hansen LA; Fersht AR; Hideg K; Gogna R; Kuppusamy P
J Biol Chem; 2018 Mar; 293(12):4262-4276. PubMed ID: 29382728
[TBL] [Abstract][Full Text] [Related]
2. HO-3867, a curcumin analog, sensitizes cisplatin-resistant ovarian carcinoma, leading to therapeutic synergy through STAT3 inhibition.
Selvendiran K; Ahmed S; Dayton A; Kuppusamy ML; Rivera BK; Kálai T; Hideg K; Kuppusamy P
Cancer Biol Ther; 2011 Nov; 12(9):837-45. PubMed ID: 21885917
[TBL] [Abstract][Full Text] [Related]
3. A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status.
Garufi A; Baldari S; Pettinari R; Gilardini Montani MS; D'Orazi V; Pistritto G; Crispini A; Giorno E; Toietta G; Marchetti F; Cirone M; D'Orazi G
J Exp Clin Cancer Res; 2020 Jun; 39(1):122. PubMed ID: 32605658
[TBL] [Abstract][Full Text] [Related]
4. Cancer therapeutic approach based on conformational stabilization of mutant p53 protein by small peptides.
Tal P; Eizenberger S; Cohen E; Goldfinger N; Pietrokovski S; Oren M; Rotter V
Oncotarget; 2016 Mar; 7(11):11817-37. PubMed ID: 26943582
[TBL] [Abstract][Full Text] [Related]
5. TAR1, a human anti-p53 single-chain antibody, restores tumor suppressor function to mutant p53 variants.
Orgad S; Dimant H; Dor-On E; Azriel-Rosenfeld R; Benhar I; Solomon B
J Immunother; 2010; 33(2):146-54. PubMed ID: 20139776
[TBL] [Abstract][Full Text] [Related]
6. Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule.
Soares J; Raimundo L; Pereira NA; Monteiro Â; Gomes S; Bessa C; Pereira C; Queiroz G; Bisio A; Fernandes J; Gomes C; Reis F; Gonçalves J; Inga A; Santos MM; Saraiva L
Oncotarget; 2016 Jan; 7(4):4326-43. PubMed ID: 26735173
[TBL] [Abstract][Full Text] [Related]
7. Antiproliferative and Apoptotic Effect of Dendrosomal Curcumin Nanoformulation in P53 Mutant and Wide-Type Cancer Cell Lines.
Montazeri M; Pilehvar-Soltanahmadi Y; Mohaghegh M; Panahi A; Khodi S; Zarghami N; Sadeghizadeh M
Anticancer Agents Med Chem; 2017; 17(5):662-673. PubMed ID: 27604683
[TBL] [Abstract][Full Text] [Related]
8. New orally active DNA minor groove binding small molecule CT-1 acts against breast cancer by targeting tumor DNA damage leading to p53-dependent apoptosis.
Saini KS; Hamidullah ; Ashraf R; Mandalapu D; Das S; Siddiqui MQ; Dwivedi S; Sarkar J; Sharma VL; Konwar R
Mol Carcinog; 2017 Apr; 56(4):1266-1280. PubMed ID: 27813185
[TBL] [Abstract][Full Text] [Related]
9. Anti-cancer efficacy of SREBP inhibitor, alone or in combination with docetaxel, in prostate cancer harboring p53 mutations.
Li X; Wu JB; Chung LW; Huang WC
Oncotarget; 2015 Dec; 6(38):41018-32. PubMed ID: 26512780
[TBL] [Abstract][Full Text] [Related]
10. Curcumin β-D-glucuronide exhibits anti-tumor effects on oxaliplatin-resistant colon cancer with less toxicity in vivo.
Ozawa-Umeta H; Kishimoto A; Imaizumi A; Hashimoto T; Asakura T; Kakeya H; Kanai M
Cancer Sci; 2020 May; 111(5):1785-1793. PubMed ID: 32163218
[TBL] [Abstract][Full Text] [Related]
11. The MDM2 Inhibitor AMG 232 Demonstrates Robust Antitumor Efficacy and Potentiates the Activity of p53-Inducing Cytotoxic Agents.
Canon J; Osgood T; Olson SH; Saiki AY; Robertson R; Yu D; Eksterowicz J; Ye Q; Jin L; Chen A; Zhou J; Cordover D; Kaufman S; Kendall R; Oliner JD; Coxon A; Radinsky R
Mol Cancer Ther; 2015 Mar; 14(3):649-58. PubMed ID: 25567130
[TBL] [Abstract][Full Text] [Related]
12. Allele-specific p53 mutant reactivation.
Yu X; Vazquez A; Levine AJ; Carpizo DR
Cancer Cell; 2012 May; 21(5):614-625. PubMed ID: 22624712
[TBL] [Abstract][Full Text] [Related]
13. The Curcumin Analog CH-5 Exerts Anticancer Effects in Human Osteosarcoma Cells via Modulation of Transcription Factors p53/Sp1.
Lima FT; Seba V; Silva G; Torrezan GS; Polaquini CR; Pinhanelli VC; Baek SJ; Fachin AL; Regasini LO; Marins M
Int J Mol Sci; 2018 Jun; 19(7):. PubMed ID: 29966255
[TBL] [Abstract][Full Text] [Related]
14. Antiproliferative Effect of a Novel 4,4'-Disulfonyldiarylidenyl Piperidone in Human Colon Cancer Cells.
Prabhat AM; Kuppusamy ML; Bognár B; Kálai T; Hideg K; Kuppusamy P
Cell Biochem Biophys; 2019 Mar; 77(1):61-67. PubMed ID: 30552554
[TBL] [Abstract][Full Text] [Related]
15. Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs.
Puca R; Nardinocchi L; Porru M; Simon AJ; Rechavi G; Leonetti C; Givol D; D'Orazi G
Cell Cycle; 2011 May; 10(10):1679-89. PubMed ID: 21508668
[TBL] [Abstract][Full Text] [Related]
16. Anti-Lung Cancer Activity of the Curcumin Analog JZ534 In Vitro.
Wu J; Cai Z; Wei X; Chen M; Ying S; Shi L; Xu RA; He F; Liang G; Zhang X
Biomed Res Int; 2015; 2015():504529. PubMed ID: 25977922
[TBL] [Abstract][Full Text] [Related]
17. p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition.
Aggarwal M; Saxena R; Asif N; Sinclair E; Tan J; Cruz I; Berry D; Kallakury B; Pham Q; Wang TTY; Chung FL
J Exp Clin Cancer Res; 2019 Jul; 38(1):307. PubMed ID: 31307507
[TBL] [Abstract][Full Text] [Related]
18. Curcumin causes superoxide anion production and p53-independent apoptosis in human colon cancer cells.
Watson JL; Hill R; Yaffe PB; Greenshields A; Walsh M; Lee PW; Giacomantonio CA; Hoskin DW
Cancer Lett; 2010 Nov; 297(1):1-8. PubMed ID: 20472336
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of a novel anticancer agent CBISC that induces DNA damage response and diminishes levels of mutant-p53.
Ronayne CT; Jonnalagadda SK; Jonnalagadda S; Nelson GL; Solano LN; Palle H; Mani C; Rumbley J; Holy J; Mereddy VR
Biochem Biophys Res Commun; 2021 Jul; 562():127-132. PubMed ID: 34051576
[TBL] [Abstract][Full Text] [Related]
20. Cellular uptake, retention and bioabsorption of HO-3867, a fluorinated curcumin analog with potential antitumor properties.
Dayton A; Selvendiran K; Kuppusamy ML; Rivera BK; Meduru S; Kálai T; Hideg K; Kuppusamy P
Cancer Biol Ther; 2010 Nov; 10(10):1027-32. PubMed ID: 20798598
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
