BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

289 related articles for article (PubMed ID: 29386106)

  • 1. Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.
    Shimada IS; Hwang SH; Somatilaka BN; Wang X; Skowron P; Kim J; Kim M; Shelton JM; Rajaram V; Xuan Z; Taylor MD; Mukhopadhyay S
    Cell Rep; 2018 Jan; 22(5):1169-1184. PubMed ID: 29386106
    [TBL] [Abstract][Full Text] [Related]  

  • 2. G-protein-coupled receptors and localized signaling in the primary cilium during ventral neural tube patterning.
    Hwang SH; Mukhopadhyay S
    Birth Defects Res A Clin Mol Teratol; 2015 Jan; 103(1):12-9. PubMed ID: 24917297
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hedgehog pathway permissive conditions allow generation of immortal cell lines from granule cells derived from cancerous and non-cancerous cerebellum.
    Heil C
    Open Biol; 2019 Jan; 9(1):180145. PubMed ID: 30958113
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Multifaceted Functions of Rab23 on Primary Cilium-Mediated and Hedgehog Signaling-Mediated Cerebellar Granule Cell Proliferation.
    Hor CHH; Lo JCW; Cham ALS; Leong WY; Goh ELK
    J Neurosci; 2021 Aug; 41(32):6850-6863. PubMed ID: 34210780
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hedgehog-mediated regulation of PPARγ controls metabolic patterns in neural precursors and shh-driven medulloblastoma.
    Bhatia B; Potts CR; Guldal C; Choi S; Korshunov A; Pfister S; Kenney AM; Nahlé ZA
    Acta Neuropathol; 2012 Apr; 123(4):587-600. PubMed ID: 22407012
    [TBL] [Abstract][Full Text] [Related]  

  • 6. YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells.
    Dey A; Robitaille M; Remke M; Maier C; Malhotra A; Gregorieff A; Wrana JL; Taylor MD; Angers S; Kenney AM
    Oncogene; 2016 Aug; 35(32):4256-68. PubMed ID: 26725322
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of Sonic hedgehog during cell proliferation in the human cerebellum.
    Haldipur P; Bharti U; Govindan S; Sarkar C; Iyengar S; Gressens P; Mani S
    Stem Cells Dev; 2012 May; 21(7):1059-68. PubMed ID: 21732818
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.
    Mukhopadhyay S; Wen X; Ratti N; Loktev A; Rangell L; Scales SJ; Jackson PK
    Cell; 2013 Jan; 152(1-2):210-23. PubMed ID: 23332756
    [TBL] [Abstract][Full Text] [Related]  

  • 9. WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation.
    Anne SL; Govek EE; Ayrault O; Kim JH; Zhu X; Murphy DA; Van Aelst L; Roussel MF; Hatten ME
    PLoS One; 2013; 8(11):e81769. PubMed ID: 24303070
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth.
    Binning MJ; Niazi T; Pedone CA; Lal B; Eberhart CG; Kim KJ; Laterra J; Fults DW
    Cancer Res; 2008 Oct; 68(19):7838-45. PubMed ID: 18829539
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The developmental stage of the medulloblastoma cell-of-origin restricts Sonic hedgehog pathway usage and drug sensitivity.
    Smit MJ; Martini TEI; Armandari I; Bočkaj I; Zomerman WW; de Camargo Magalhães ES; Siragna Z; Meeuwsen TGJ; Scherpen FJG; Schoots MH; Ritsema M; den Dunnen WFA; Hoving EW; Paridaen JTML; de Haan G; Guryev V; Bruggeman SWM
    J Cell Sci; 2022 Jun; 135(11):. PubMed ID: 35535520
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sox2 requirement in sonic hedgehog-associated medulloblastoma.
    Ahlfeld J; Favaro R; Pagella P; Kretzschmar HA; Nicolis S; Schüller U
    Cancer Res; 2013 Jun; 73(12):3796-807. PubMed ID: 23596255
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.
    Conduit SE; Ramaswamy V; Remke M; Watkins DN; Wainwright BJ; Taylor MD; Mitchell CA; Dyson JM
    Oncogene; 2017 Oct; 36(43):5969-5984. PubMed ID: 28650469
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Primary Cilia in the Murine Cerebellum and in Mutant Models of Medulloblastoma.
    Di Pietro C; Marazziti D; La Sala G; Abbaszadeh Z; Golini E; Matteoni R; Tocchini-Valentini GP
    Cell Mol Neurobiol; 2017 Jan; 37(1):145-154. PubMed ID: 26935062
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Disruption of the ciliary GTPase Arl13b suppresses Sonic hedgehog overactivation and inhibits medulloblastoma formation.
    Bay SN; Long AB; Caspary T
    Proc Natl Acad Sci U S A; 2018 Feb; 115(7):1570-1575. PubMed ID: 29378965
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Shh receptor Boc promotes progression of early medulloblastoma to advanced tumors.
    Mille F; Tamayo-Orrego L; Lévesque M; Remke M; Korshunov A; Cardin J; Bouchard N; Izzi L; Kool M; Northcott PA; Taylor MD; Pfister SM; Charron F
    Dev Cell; 2014 Oct; 31(1):34-47. PubMed ID: 25263791
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma.
    Bhatia B; Hsieh M; Kenney AM; Nahlé Z
    Oncogene; 2011 Jan; 30(4):410-22. PubMed ID: 20890301
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice.
    Rao G; Pedone CA; Del Valle L; Reiss K; Holland EC; Fults DW
    Oncogene; 2004 Aug; 23(36):6156-62. PubMed ID: 15195141
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression.
    Milla LA; Arros A; Espinoza N; Remke M; Kool M; Taylor MD; Pfister SM; Wainwright BJ; Palma V
    Int J Cancer; 2014 Jan; 134(1):21-31. PubMed ID: 23775842
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities.
    Shimada IS; Somatilaka BN; Hwang SH; Anderson AG; Shelton JM; Rajaram V; Konopka G; Mukhopadhyay S
    Dev Biol; 2019 Jun; 450(1):47-62. PubMed ID: 30914320
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.