These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 29394115)

  • 1. Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.
    Li F; Xu D; Wang Y; Zhou Z; Liu J; Hu S; Gong Y; Yuan J; Pan L
    Autophagy; 2018; 14(1):66-79. PubMed ID: 29394115
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism.
    Shen WC; Li HY; Chen GC; Chern Y; Tu PH
    Autophagy; 2015 Apr; 11(4):685-700. PubMed ID: 25484089
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria.
    Richter B; Sliter DA; Herhaus L; Stolz A; Wang C; Beli P; Zaffagnini G; Wild P; Martens S; Wagner SA; Youle RJ; Dikic I
    Proc Natl Acad Sci U S A; 2016 Apr; 113(15):4039-44. PubMed ID: 27035970
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of a splice variant of optineurin which is defective in autophagy and phosphorylation.
    Moharir SC; Bansal M; Ramachandran G; Ramaswamy R; Rawat S; Raychaudhuri S; Swarup G
    Biochim Biophys Acta Mol Cell Res; 2018 Nov; 1865(11 Pt A):1526-1538. PubMed ID: 30327196
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin.
    Sirohi K; Kumari A; Radha V; Swarup G
    PLoS One; 2015; 10(9):e0138289. PubMed ID: 26376340
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.
    Nakazawa S; Oikawa D; Ishii R; Ayaki T; Takahashi H; Takeda H; Ishitani R; Kamei K; Takeyoshi I; Kawakami H; Iwai K; Hatada I; Sawasaki T; Ito H; Nureki O; Tokunaga F
    Nat Commun; 2016 Aug; 7():12547. PubMed ID: 27552911
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy.
    Moore AS; Holzbaur EL
    Proc Natl Acad Sci U S A; 2016 Jun; 113(24):E3349-58. PubMed ID: 27247382
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
    Li F; Xie X; Wang Y; Liu J; Cheng X; Guo Y; Gong Y; Hu S; Pan L
    Nat Commun; 2016 Sep; 7():12708. PubMed ID: 27620379
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional analysis of optineurin and some of its disease-associated mutants.
    Bansal M; Swarup G; Balasubramanian D
    IUBMB Life; 2015 Feb; 67(2):120-8. PubMed ID: 25855473
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altered Functions and Interactions of Glaucoma-Associated Mutants of Optineurin.
    Swarup G; Sayyad Z
    Front Immunol; 2018; 9():1287. PubMed ID: 29951055
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A glaucoma- and ALS-associated mutant of OPTN induces neuronal cell death dependent on Tbk1 activity, autophagy and ER stress.
    Medchalmi S; Tare P; Sayyad Z; Swarup G
    FEBS J; 2021 Aug; 288(15):4576-4595. PubMed ID: 33548116
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates.
    Korac J; Schaeffer V; Kovacevic I; Clement AM; Jungblut B; Behl C; Terzic J; Dikic I
    J Cell Sci; 2013 Jan; 126(Pt 2):580-92. PubMed ID: 23178947
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interaction between optineurin and Rab1a regulates autophagosome formation in neuroblastoma cells.
    Song GJ; Jeon H; Seo M; Jo M; Suk K
    J Neurosci Res; 2018 Mar; 96(3):407-415. PubMed ID: 28843006
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A critical role of Hrd1 in the regulation of optineurin degradation and aggresome formation.
    Mao J; Xia Q; Liu C; Ying Z; Wang H; Wang G
    Hum Mol Genet; 2017 May; 26(10):1877-1889. PubMed ID: 28334804
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Significance of optineurin mutations in glaucoma and other diseases.
    Minegishi Y; Nakayama M; Iejima D; Kawase K; Iwata T
    Prog Retin Eye Res; 2016 Nov; 55():149-181. PubMed ID: 27693724
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of Optineurin in the Mitochondrial Dysfunction: Potential Implications in Neurodegenerative Diseases and Cancer.
    Weil R; Laplantine E; Curic S; Génin P
    Front Immunol; 2018; 9():1243. PubMed ID: 29971063
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.
    Wong YC; Holzbaur EL
    Proc Natl Acad Sci U S A; 2014 Oct; 111(42):E4439-48. PubMed ID: 25294927
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Optineurin: The autophagy connection.
    Ying H; Yue BY
    Exp Eye Res; 2016 Mar; 144():73-80. PubMed ID: 26142952
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy.
    Heo JM; Ordureau A; Paulo JA; Rinehart J; Harper JW
    Mol Cell; 2015 Oct; 60(1):7-20. PubMed ID: 26365381
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dysfunction of Optineurin in Amyotrophic Lateral Sclerosis and Glaucoma.
    Toth RP; Atkin JD
    Front Immunol; 2018; 9():1017. PubMed ID: 29875767
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.