264 related articles for article (PubMed ID: 29394289)
1. Lapachol inhibits glycolysis in cancer cells by targeting pyruvate kinase M2.
Shankar Babu M; Mahanta S; Lakhter AJ; Hato T; Paul S; Naidu SR
PLoS One; 2018; 13(2):e0191419. PubMed ID: 29394289
[TBL] [Abstract][Full Text] [Related]
2. Shikonin Inhibits Tumor Growth in Mice by Suppressing Pyruvate Kinase M2-mediated Aerobic Glycolysis.
Zhao X; Zhu Y; Hu J; Jiang L; Li L; Jia S; Zen K
Sci Rep; 2018 Sep; 8(1):14517. PubMed ID: 30266938
[TBL] [Abstract][Full Text] [Related]
3. Ferroxitosis: a cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma.
Lakhter AJ; Hamilton J; Dagher PC; Mukkamala S; Hato T; Dong XC; Mayo LD; Harris RA; Shekhar A; Ivan M; Brustovetsky N; Naidu SR
Oncotarget; 2014 Dec; 5(24):12694-703. PubMed ID: 25587028
[TBL] [Abstract][Full Text] [Related]
4. Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2.
Chen J; Xie J; Jiang Z; Wang B; Wang Y; Hu X
Oncogene; 2011 Oct; 30(42):4297-306. PubMed ID: 21516121
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and antitumor activity of novel 2, 3-didithiocarbamate substituted naphthoquinones as inhibitors of pyruvate kinase M2 isoform.
Ning X; Qi H; Li R; Jin Y; McNutt MA; Yin Y
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):126-129. PubMed ID: 29185365
[TBL] [Abstract][Full Text] [Related]
6. Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line.
Yang W; Liu J; Hou L; Chen Q; Liu Y
Life Sci; 2021 Jan; 265():118796. PubMed ID: 33220292
[TBL] [Abstract][Full Text] [Related]
7. Pyruvate kinase M2 is a poor prognostic marker of and a therapeutic target in ovarian cancer.
Chao TK; Huang TS; Liao YP; Huang RL; Su PH; Shen HY; Lai HC; Wang YC
PLoS One; 2017; 12(7):e0182166. PubMed ID: 28753677
[TBL] [Abstract][Full Text] [Related]
8. PKM2 inhibitor shikonin suppresses TPA-induced mitochondrial malfunction and proliferation of skin epidermal JB6 cells.
Li W; Liu J; Zhao Y
Mol Carcinog; 2014 May; 53(5):403-12. PubMed ID: 23255458
[TBL] [Abstract][Full Text] [Related]
9. Shikonin inhibited glycolysis and sensitized cisplatin treatment in non-small cell lung cancer cells via the exosomal pyruvate kinase M2 pathway.
Dai Y; Liu Y; Li J; Jin M; Yang H; Huang G
Bioengineered; 2022 May; 13(5):13906-13918. PubMed ID: 35706397
[TBL] [Abstract][Full Text] [Related]
10. Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.
Zhang H; Wang D; Li M; Plecitá-Hlavatá L; D'Alessandro A; Tauber J; Riddle S; Kumar S; Flockton A; McKeon BA; Frid MG; Reisz JA; Caruso P; El Kasmi KC; Ježek P; Morrell NW; Hu CJ; Stenmark KR
Circulation; 2017 Dec; 136(25):2468-2485. PubMed ID: 28972001
[TBL] [Abstract][Full Text] [Related]
11. Benserazide is a novel inhibitor targeting PKM2 for melanoma treatment.
Zhou Y; Huang Z; Su J; Li J; Zhao S; Wu L; Zhang J; He Y; Zhang G; Tao J; Zhou J; Chen X; Peng C
Int J Cancer; 2020 Jul; 147(1):139-151. PubMed ID: 31652354
[TBL] [Abstract][Full Text] [Related]
12. Tumor M2-PK: A novel urine marker of bladder cancer.
Liu W; Woolbright BL; Pirani K; Didde R; Abbott E; Kaushik G; Martin P; Hamilton-Reeves J; Taylor JA; Holzbeierlein JM; Anant S; Lee EK
PLoS One; 2019; 14(6):e0218737. PubMed ID: 31246990
[TBL] [Abstract][Full Text] [Related]
13. Identification of small molecule inhibitors of pyruvate kinase M2.
Vander Heiden MG; Christofk HR; Schuman E; Subtelny AO; Sharfi H; Harlow EE; Xian J; Cantley LC
Biochem Pharmacol; 2010 Apr; 79(8):1118-24. PubMed ID: 20005212
[TBL] [Abstract][Full Text] [Related]
14. Apigenin Restrains Colon Cancer Cell Proliferation via Targeted Blocking of Pyruvate Kinase M2-Dependent Glycolysis.
Shan S; Shi J; Yang P; Jia B; Wu H; Zhang X; Li Z
J Agric Food Chem; 2017 Sep; 65(37):8136-8144. PubMed ID: 28829588
[TBL] [Abstract][Full Text] [Related]
15. Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells.
Wang CC; Chiang YM; Sung SC; Hsu YL; Chang JK; Kuo PL
Cancer Lett; 2008 Jan; 259(1):82-98. PubMed ID: 18023967
[TBL] [Abstract][Full Text] [Related]
16. Discovery of novel naphthoquinone derivatives as inhibitors of the tumor cell specific M2 isoform of pyruvate kinase.
Ning X; Qi H; Li R; Li Y; Jin Y; McNutt MA; Liu J; Yin Y
Eur J Med Chem; 2017 Sep; 138():343-352. PubMed ID: 28688274
[TBL] [Abstract][Full Text] [Related]
17. Identification of Gliotoxin isolated from marine fungus as a new pyruvate kinase M2 inhibitor.
Tang W; Liu ZL; Mai XY; Qi X; Li DH; Gu QQ; Li J
Biochem Biophys Res Commun; 2020 Jul; 528(3):594-600. PubMed ID: 32507600
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of Pyruvate Kinase M2 Markedly Reduces Chemoresistance of Advanced Bladder Cancer to Cisplatin.
Wang X; Zhang F; Wu XR
Sci Rep; 2017 Apr; 7():45983. PubMed ID: 28378811
[TBL] [Abstract][Full Text] [Related]
19. Pyruvate kinase M2: multiple faces for conferring benefits on cancer cells.
Tamada M; Suematsu M; Saya H
Clin Cancer Res; 2012 Oct; 18(20):5554-61. PubMed ID: 23071357
[TBL] [Abstract][Full Text] [Related]
20. Specific Pyruvate Kinase M2 Inhibitor, Compound 3K, Induces Autophagic Cell Death through Disruption of the Glycolysis Pathway in Ovarian Cancer Cells.
Park JH; Kundu A; Lee SH; Jiang C; Lee SH; Kim YS; Kyung SY; Park SH; Kim HS
Int J Biol Sci; 2021; 17(8):1895-1908. PubMed ID: 34131394
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
