BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 29395969)

  • 1. Design, synthesis and biological evaluation of novel pyrazolo-oxothiazolidine derivatives as antiproliferative agents against human lung cancer cell line A549.
    Yakaiah S; Sagar Vijay Kumar P; Baby Rani P; Durga Prasad K; Aparna P
    Bioorg Med Chem Lett; 2018 Feb; 28(4):630-636. PubMed ID: 29395969
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and antitumor activity of Novel Sorafenib derivatives bearing pyrazole scaffold.
    Wang M; Xu S; Lei H; Wang C; Xiao Z; Jia S; Zhi J; Zheng P; Zhu W
    Bioorg Med Chem; 2017 Oct; 25(20):5754-5763. PubMed ID: 28927801
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, activity and docking studies of phenylpyrimidine-carboxamide Sorafenib derivatives.
    Wang W; Wu C; Wang J; Luo R; Wang C; Liu X; Li J; Zhu W; Zheng P
    Bioorg Med Chem; 2016 Dec; 24(23):6166-6173. PubMed ID: 28340913
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and anticancer evaluation of 1H-pyrazolo[3,4-d]pyrimidine derivatives as potent EGFR
    Gaber AA; Bayoumi AH; El-Morsy AM; Sherbiny FF; Mehany ABM; Eissa IH
    Bioorg Chem; 2018 Oct; 80():375-395. PubMed ID: 29986185
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives.
    Bakr RB; Mehany ABM; Abdellatif KRA
    Anticancer Agents Med Chem; 2017; 17(10):1389-1400. PubMed ID: 28270084
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of stable benzimidazole derivatives bearing pyrazole as anticancer and EGFR receptor inhibitors.
    Akhtar MJ; Khan AA; Ali Z; Dewangan RP; Rafi M; Hassan MQ; Akhtar MS; Siddiqui AA; Partap S; Pasha S; Yar MS
    Bioorg Chem; 2018 Aug; 78():158-169. PubMed ID: 29571113
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel 2-(5-Aryl-4,5-Dihydropyrazol-1-yl)thiazol-4-One as EGFR Inhibitors: Synthesis, Biological Assessment and Molecular Docking Insights.
    Al-Warhi T; El Kerdawy AM; Said MA; Albohy A; Elsayed ZM; Aljaeed N; Elkaeed EB; Eldehna WM; Abdel-Aziz HA; Abdelmoaz MA
    Drug Des Devel Ther; 2022; 16():1457-1471. PubMed ID: 35607598
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of diaryl urea derivatives designed as potential anticarcinoma agents using de novo structure-based lead optimization approach.
    Azimian F; Hamzeh-Mivehroud M; Shahbazi Mojarrad J; Hemmati S; Dastmalchi S
    Eur J Med Chem; 2020 Sep; 201():112461. PubMed ID: 32663641
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and biological evaluation of some new 1,3,4-thiadiazine-thiourea derivatives as potential antitumor agents against non-small cell lung cancer cells.
    Ragab FAF; Abdel-Aziz SA; Kamel M; Ouf AMA; Allam HA
    Bioorg Chem; 2019 Dec; 93():103323. PubMed ID: 31586713
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel piperazine-chalcone hybrids and related pyrazoline analogues targeting VEGFR-2 kinase; design, synthesis, molecular docking studies, and anticancer evaluation.
    Ahmed MF; Santali EY; El-Haggar R
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):307-318. PubMed ID: 33349069
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, Biological Evaluation and Docking Studies of Sorafenib Derivatives N-(3-fluoro-4-(pyridin-4-yloxy)phenyl)-4(5)-phenylpicolinamides.
    Wang M; Wu C; Xu S; Zhu Y; Li W; Zheng P; Zhu W
    Med Chem; 2017; 13(2):176-185. PubMed ID: 27855595
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, Synthesis, Activity and Docking Study of Sorafenib Analogs Bearing Sulfonylurea Unit.
    Wu C; Wang M; Tang Q; Luo R; Chen L; Zheng P; Zhu W
    Molecules; 2015 Oct; 20(10):19361-71. PubMed ID: 26512636
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biological Validation of Novel Polysubstituted Pyrazole Candidates with in Vitro Anticancer Activities.
    Fahmy HH; Khalifa NM; Ismail MM; El-Sahrawy HM; Nossier ES
    Molecules; 2016 Feb; 21(3):271. PubMed ID: 26927048
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and evaluation of novel 2-(1H-imidazol-2-yl) pyridine Sorafenib derivatives as potential BRAF inhibitors and anti-tumor agents.
    Jiao Y; Xin BT; Zhang Y; Wu J; Lu X; Zheng Y; Tang W; Zhou X
    Eur J Med Chem; 2015 Jan; 90():170-83. PubMed ID: 25461318
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanistic selectivity investigation and 2D-QSAR study of some new antiproliferative pyrazoles and pyrazolopyridines as potential CDK2 inhibitors.
    Hassan GS; Georgey HH; Mohammed EZ; George RF; Mahmoud WR; Omar FA
    Eur J Med Chem; 2021 Jun; 218():113389. PubMed ID: 33784602
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents.
    Abdelgawad MA; Bakr RB; Omar HA
    Bioorg Chem; 2017 Oct; 74():82-90. PubMed ID: 28772160
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, Synthesis and Biological Evaluation of Benzohydrazide Derivatives Containing Dihydropyrazoles as Potential EGFR Kinase Inhibitors.
    Wang HC; Yan XQ; Yan TL; Li HX; Wang ZC; Zhu HL
    Molecules; 2016 Aug; 21(8):. PubMed ID: 27527130
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and activity of novel sorafenib analogues bearing chalcone unit.
    Wang M; Xu S; Wu C; Liu X; Tao H; Huang Y; Liu Y; Zheng P; Zhu W
    Bioorg Med Chem Lett; 2016 Nov; 26(22):5450-5454. PubMed ID: 27777009
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, anticancer assessment on human breast, liver and colon carcinoma cell lines and molecular modeling study using novel pyrazolo[4,3-c]pyridine derivatives.
    Metwally NH; Deeb EA
    Bioorg Chem; 2018 Apr; 77():203-214. PubMed ID: 29367077
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Iodine mediated pyrazolo-quinoline derivatives as potent anti-proliferative agents.
    Kasaboina S; Ramineni V; Banu S; Bandi Y; Nagarapu L; Dumala N; Grover P
    Bioorg Med Chem Lett; 2018 Feb; 28(4):664-667. PubMed ID: 29409753
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.