These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

273 related articles for article (PubMed ID: 29396391)

  • 1. Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe.
    Pietrobono S; Santini R; Gagliardi S; Dapporto F; Colecchia D; Chiariello M; Leone C; Valoti M; Manetti F; Petricci E; Taddei M; Stecca B
    Cell Death Dis; 2018 Feb; 9(2):142. PubMed ID: 29396391
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma.
    Pietrobono S; Gaudio E; Gagliardi S; Zitani M; Carrassa L; Migliorini F; Petricci E; Manetti F; Makukhin N; Bond AG; Paradise BD; Ciulli A; Fernandez-Zapico ME; Bertoni F; Stecca B
    Oncogene; 2021 Jun; 40(22):3799-3814. PubMed ID: 33958721
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance.
    Gruber W; Hutzinger M; Elmer DP; Parigger T; Sternberg C; Cegielkowski L; Zaja M; Leban J; Michel S; Hamm S; Vitt D; Aberger F
    Oncotarget; 2016 Feb; 7(6):7134-48. PubMed ID: 26784250
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype.
    Infante P; Alfonsi R; Ingallina C; Quaglio D; Ghirga F; D'Acquarica I; Bernardi F; Di Magno L; Canettieri G; Screpanti I; Gulino A; Botta B; Mori M; Di Marcotullio L
    Cell Death Dis; 2016 Sep; 7(9):e2376. PubMed ID: 27899820
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.
    Benvenuto M; Masuelli L; De Smaele E; Fantini M; Mattera R; Cucchi D; Bonanno E; Di Stefano E; Frajese GV; Orlandi A; Screpanti I; Gulino A; Modesti A; Bei R
    Oncotarget; 2016 Feb; 7(8):9250-70. PubMed ID: 26843616
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting class I histone deacetylases by the novel small molecule inhibitor 4SC-202 blocks oncogenic hedgehog-GLI signaling and overcomes smoothened inhibitor resistance.
    Gruber W; Peer E; Elmer DP; Sternberg C; Tesanovic S; Del Burgo P; Coni S; Canettieri G; Neureiter D; Bartz R; Kohlhof H; Vitt D; Aberger F
    Int J Cancer; 2018 Mar; 142(5):968-975. PubMed ID: 29055107
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cells.
    Santini R; Vinci MC; Pandolfi S; Penachioni JY; Montagnani V; Olivito B; Gattai R; Pimpinelli N; Gerlini G; Borgognoni L; Stecca B
    Stem Cells; 2012 Sep; 30(9):1808-18. PubMed ID: 22730244
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interference with SMO increases chemotherapy drug sensitivity of A2780/DDP cells by inhibiting the Hh/Gli signaling pathway.
    Ma S; Liu D; Tan W; Du B; Liu W; Li W; Jiao Y
    J Cell Biochem; 2020 Jun; 121(5-6):3256-3265. PubMed ID: 31904145
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Jervine exhibits anticancer effects on nasopharyngeal carcinoma through promoting autophagic apoptosis via the blockage of Hedgehog signaling.
    Chen J; Wen B; Wang Y; Wu S; Zhang X; Gu Y; Wang Z; Wang J; Zhang W; Yong J
    Biomed Pharmacother; 2020 Dec; 132():110898. PubMed ID: 33113432
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gli as a novel therapeutic target in malignant pleural mesothelioma.
    Li H; Lui N; Cheng T; Tseng HH; Yue D; Giroux-Leprieur E; Do HT; Sheng Q; Jin JQ; Luh TW; Jablons DM; He B
    PLoS One; 2013; 8(3):e57346. PubMed ID: 23483902
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo.
    Jalili A; Mertz KD; Romanov J; Wagner C; Kalthoff F; Stuetz A; Pathria G; Gschaider M; Stingl G; Wagner SN
    PLoS One; 2013; 8(7):e69064. PubMed ID: 23935925
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of inhibition of hedgehog signaling on cell growth and migration of uveal melanoma cells.
    Duan F; Lin M; Li C; Ding X; Qian G; Zhang H; Ge S; Fan X; Li J
    Cancer Biol Ther; 2014 May; 15(5):544-59. PubMed ID: 24553082
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, Synthesis and Biological Evaluation of novel Hedgehog Inhibitors for treating Pancreatic Cancer.
    Kumar V; Chaudhary AK; Dong Y; Zhong HA; Mondal G; Lin F; Kumar V; Mahato RI
    Sci Rep; 2017 May; 7(1):1665. PubMed ID: 28490735
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway.
    Chen J; Lv H; Hu J; Ji M; Xue N; Li C; Ma S; Zhou Q; Lin B; Li Y; Yu S; Chen X
    Cancer Lett; 2016 Oct; 381(2):391-403. PubMed ID: 27495899
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel smoothened antagonists as anti-neoplastic agents for the treatment of osteosarcoma.
    Bernardini G; Geminiani M; Gambassi S; Orlandini M; Petricci E; Marzocchi B; Laschi M; Taddei M; Manetti F; Santucci A
    J Cell Physiol; 2018 Jun; 233(6):4961-4971. PubMed ID: 29215700
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel-smoothened inhibitors for therapeutic targeting of naïve and drug-resistant hedgehog pathway-driven cancers.
    Li QR; Zhao H; Zhang XS; Lang H; Yu K
    Acta Pharmacol Sin; 2019 Feb; 40(2):257-267. PubMed ID: 29777201
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo.
    Wickström M; Dyberg C; Shimokawa T; Milosevic J; Baryawno N; Fuskevåg OM; Larsson R; Kogner P; Zaphiropoulos PG; Johnsen JI
    Int J Cancer; 2013 Apr; 132(7):1516-24. PubMed ID: 22949014
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LncRNA-cCSC1 modulates cancer stem cell properties in colorectal cancer via activation of the Hedgehog signaling pathway.
    Zhou H; Xiong Y; Peng L; Wang R; Zhang H; Fu Z
    J Cell Biochem; 2020 Mar; 121(3):2510-2524. PubMed ID: 31680315
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Hedgehog signalling pathway mediates drug response of MCF-7 mammosphere cells in breast cancer patients.
    He M; Fu Y; Yan Y; Xiao Q; Wu H; Yao W; Zhao H; Zhao L; Jiang Q; Yu Z; Jin F; Mi X; Wang E; Cui Z; Fu L; Chen J; Wei M
    Clin Sci (Lond); 2015 Nov; 129(9):809-22. PubMed ID: 26201092
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hedgehog Signaling and Truncated GLI1 in Cancer.
    Doheny D; Manore SG; Wong GL; Lo HW
    Cells; 2020 Sep; 9(9):. PubMed ID: 32957513
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.