These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
177 related articles for article (PubMed ID: 29397068)
1. A mechanism for agonist activation of the glucagon-like peptide-1 (GLP-1) receptor through modelling & molecular dynamics. Gómez Santiago C; Paci E; Donnelly D Biochem Biophys Res Commun; 2018 Mar; 498(2):359-365. PubMed ID: 29397068 [TBL] [Abstract][Full Text] [Related]
2. Investigation of ECD conformational transition mechanism of GLP-1R by molecular dynamics simulations and Markov state model. Zhang J; Bai Q; Pérez-Sánchez H; Shang S; An X; Yao X Phys Chem Chem Phys; 2019 Apr; 21(16):8470-8481. PubMed ID: 30957116 [TBL] [Abstract][Full Text] [Related]
3. Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein. Zhang Y; Sun B; Feng D; Hu H; Chu M; Qu Q; Tarrasch JT; Li S; Sun Kobilka T; Kobilka BK; Skiniotis G Nature; 2017 Jun; 546(7657):248-253. PubMed ID: 28538729 [TBL] [Abstract][Full Text] [Related]
4. Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R). Yang D; de Graaf C; Yang L; Song G; Dai A; Cai X; Feng Y; Reedtz-Runge S; Hanson MA; Yang H; Jiang H; Stevens RC; Wang MW J Biol Chem; 2016 Jun; 291(25):12991-3004. PubMed ID: 27059958 [TBL] [Abstract][Full Text] [Related]
5. Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex. Liang YL; Khoshouei M; Glukhova A; Furness SGB; Zhao P; Clydesdale L; Koole C; Truong TT; Thal DM; Lei S; Radjainia M; Danev R; Baumeister W; Wang MW; Miller LJ; Christopoulos A; Sexton PM; Wootten D Nature; 2018 Mar; 555(7694):121-125. PubMed ID: 29466332 [TBL] [Abstract][Full Text] [Related]
6. Cryo-EM structure of the dual incretin receptor agonist, peptide-19, in complex with the glucagon-like peptide-1 receptor. Johnson RM; Zhang X; Piper SJ; Nettleton TJ; Vandekolk TH; Langmead CJ; Danev R; Sexton PM; Wootten D Biochem Biophys Res Commun; 2021 Nov; 578():84-90. PubMed ID: 34547628 [TBL] [Abstract][Full Text] [Related]
7. Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide. Chang R; Zhang X; Qiao A; Dai A; Belousoff MJ; Tan Q; Shao L; Zhong L; Lin G; Liang YL; Ma L; Han S; Yang D; Danev R; Wang MW; Wootten D; Wu B; Sexton PM J Biol Chem; 2020 Jul; 295(28):9313-9325. PubMed ID: 32371397 [TBL] [Abstract][Full Text] [Related]
8. The peptide agonist-binding site of the glucagon-like peptide-1 (GLP-1) receptor based on site-directed mutagenesis and knowledge-based modelling. Dods RL; Donnelly D Biosci Rep; 2015 Nov; 36(1):e00285. PubMed ID: 26598711 [TBL] [Abstract][Full Text] [Related]
9. α-Helix or β-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4. Oddo A; Mortensen S; Thøgersen H; De Maria L; Hennen S; McGuire JN; Kofoed J; Linderoth L; Reedtz-Runge S Biochemistry; 2018 Jul; 57(28):4148-4154. PubMed ID: 29877701 [TBL] [Abstract][Full Text] [Related]
10. The G Protein-First Mechanism for Activation of the Class B Glucagon-like Peptide 1 Receptor Coupled to N-Terminal Domain-Mediated Conformational Progression. Li B; Yang MY; Kim SK; Goddard WA J Am Chem Soc; 2024 Sep; 146(38):26251-26260. PubMed ID: 39266057 [TBL] [Abstract][Full Text] [Related]
11. Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism. Lei S; Clydesdale L; Dai A; Cai X; Feng Y; Yang D; Liang YL; Koole C; Zhao P; Coudrat T; Christopoulos A; Wang MW; Wootten D; Sexton PM J Biol Chem; 2018 Jun; 293(24):9370-9387. PubMed ID: 29717000 [TBL] [Abstract][Full Text] [Related]
12. Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation. Deganutti G; Liang YL; Zhang X; Khoshouei M; Clydesdale L; Belousoff MJ; Venugopal H; Truong TT; Glukhova A; Keller AN; Gregory KJ; Leach K; Christopoulos A; Danev R; Reynolds CA; Zhao P; Sexton PM; Wootten D Nat Commun; 2022 Jan; 13(1):92. PubMed ID: 35013280 [TBL] [Abstract][Full Text] [Related]
13. Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Song G; Yang D; Wang Y; de Graaf C; Zhou Q; Jiang S; Liu K; Cai X; Dai A; Lin G; Liu D; Wu F; Wu Y; Zhao S; Ye L; Han GW; Lau J; Wu B; Hanson MA; Liu ZJ; Wang MW; Stevens RC Nature; 2017 Jun; 546(7657):312-315. PubMed ID: 28514449 [TBL] [Abstract][Full Text] [Related]
14. Crystal structure of the GLP-1 receptor bound to a peptide agonist. Jazayeri A; Rappas M; Brown AJH; Kean J; Errey JC; Robertson NJ; Fiez-Vandal C; Andrews SP; Congreve M; Bortolato A; Mason JS; Baig AH; Teobald I; Doré AS; Weir M; Cooke RM; Marshall FH Nature; 2017 Jun; 546(7657):254-258. PubMed ID: 28562585 [TBL] [Abstract][Full Text] [Related]
15. Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes. Zhang X; Belousoff MJ; Liang YL; Danev R; Sexton PM; Wootten D Cell Rep; 2021 Jul; 36(2):109374. PubMed ID: 34260945 [TBL] [Abstract][Full Text] [Related]
16. Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Zhang X; Belousoff MJ; Zhao P; Kooistra AJ; Truong TT; Ang SY; Underwood CR; Egebjerg T; Šenel P; Stewart GD; Liang YL; Glukhova A; Venugopal H; Christopoulos A; Furness SGB; Miller LJ; Reedtz-Runge S; Langmead CJ; Gloriam DE; Danev R; Sexton PM; Wootten D Mol Cell; 2020 Nov; 80(3):485-500.e7. PubMed ID: 33027691 [TBL] [Abstract][Full Text] [Related]