BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 29400267)

  • 1. Trypanosoma cruzi: death phenotypes induced by ortho-naphthoquinone substrates of the aldo-keto reductase (TcAKR). Role of this enzyme in the mechanism of action of β-lapachone.
    Garavaglia PA; Rubio MF; Laverrière M; Tasso LM; Fichera LE; Cannata JJB; García GA
    Parasitology; 2018 Aug; 145(9):1251-1259. PubMed ID: 29400267
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Putative Role of the Aldo-Keto Reductase from Trypanosoma cruzi in Benznidazole Metabolism.
    Garavaglia PA; Laverrière M; Cannata JJ; García GA
    Antimicrob Agents Chemother; 2016 May; 60(5):2664-70. PubMed ID: 26856844
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification, cloning and characterization of an aldo-keto reductase from Trypanosoma cruzi with quinone oxido-reductase activity.
    Garavaglia PA; Cannata JJ; Ruiz AM; Maugeri D; Duran R; Galleano M; García GA
    Mol Biochem Parasitol; 2010 Oct; 173(2):132-41. PubMed ID: 20595031
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Trypanosoma cruzi: insights into naphthoquinone effects on growth and proteinase activity.
    Bourguignon SC; Cavalcanti DF; de Souza AM; Castro HC; Rodrigues CR; Albuquerque MG; Santos DO; da Silva GG; da Silva FC; Ferreira VF; de Pinho RT; Alves CR
    Exp Parasitol; 2011 Jan; 127(1):160-6. PubMed ID: 20647011
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial disfunction and ROS production are essential for anti-Trypanosoma cruzi activity of β-lapachone-derived naphthoimidazoles.
    Bombaça ACS; Viana PG; Santos ACC; Silva TL; Rodrigues ABM; Guimarães ACR; Goulart MOF; da Silva Júnior EN; Menna-Barreto RFS
    Free Radic Biol Med; 2019 Jan; 130():408-418. PubMed ID: 30445126
    [TBL] [Abstract][Full Text] [Related]  

  • 6. New Insights into the Role of the
    Díaz-Viraqué F; Chiribao ML; Paes-Vieira L; Machado MR; Faral-Tello P; Tomasina R; Trochine A; Robello C
    Pathogens; 2023 Jan; 12(1):. PubMed ID: 36678433
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Trypanosoma cruzi mitochondrial swelling and membrane potential collapse as primary evidence of the mode of action of naphthoquinone analogues.
    Salomão K; De Santana NA; Molina MT; De Castro SL; Menna-Barreto RF
    BMC Microbiol; 2013 Sep; 13():196. PubMed ID: 24004461
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel N,N-di-alkylnaphthoimidazolium derivative of β-lapachone impaired Trypanosoma cruzi mitochondrial electron transport system.
    Bombaça ACS; Silva LA; Chaves OA; da Silva LS; Barbosa JMC; da Silva AM; Ferreira ABB; Menna-Barreto RFS
    Biomed Pharmacother; 2021 Mar; 135():111186. PubMed ID: 33395606
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Trypanosoma cruzi: in vitro activity of Epoxy-alpha-Lap, a derivative of alpha-lapachone, on trypomastigote and amastigote forms.
    Bourguignon SC; Castro HC; Santos DO; Alves CR; Ferreira VF; Gama IL; Silva FC; Seguins WS; Pinho RT
    Exp Parasitol; 2009 Jun; 122(2):91-6. PubMed ID: 19285074
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A role for trypanosomatid aldo-keto reductases in methylglyoxal, prostaglandin and isoprostane metabolism.
    Roberts AJ; Dunne J; Scullion P; Norval S; Fairlamb AH
    Biochem J; 2018 Aug; 475(16):2593-2610. PubMed ID: 30045874
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound.
    Lara LS; Moreira CS; Calvet CM; Lechuga GC; Souza RS; Bourguignon SC; Ferreira VF; Rocha D; Pereira MCS
    Eur J Med Chem; 2018 Jan; 144():572-581. PubMed ID: 29289882
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of a novel β-lapachone derivative on Trypanosoma cruzi: Parasite death involving apoptosis, autophagy and necrosis.
    Dos Anjos DO; Sobral Alves ES; Gonçalves VT; Fontes SS; Nogueira ML; Suarez-Fontes AM; Neves da Costa JB; Rios-Santos F; Vannier-Santos MA
    Int J Parasitol Drugs Drug Resist; 2016 Dec; 6(3):207-219. PubMed ID: 27770751
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural analysis and molecular docking of trypanocidal aryloxy-quinones in trypanothione and glutathione reductases: a comparison with biochemical data.
    Vera B; Vázquez K; Mascayano C; Tapia RA; Espinosa V; Soto-Delgado J; Salas CO; Paulino M
    J Biomol Struct Dyn; 2017 Jun; 35(8):1785-1803. PubMed ID: 27232454
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aldo-keto reductase and alcohol dehydrogenase contribute to benznidazole natural resistance in Trypanosoma cruzi.
    González L; García-Huertas P; Triana-Chávez O; García GA; Murta SMF; Mejía-Jaramillo AM
    Mol Microbiol; 2017 Dec; 106(5):704-718. PubMed ID: 28884498
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization and trypanocidal activity of a β-lapachone-containing drug carrier.
    Barbosa JMC; Nicoletti CD; da Silva PB; Melo TG; Futuro DO; Ferreira VF; Salomão K
    PLoS One; 2021; 16(3):e0246811. PubMed ID: 33661933
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oxyrane derivative of alpha-lapachone is potent growth inhibitor of Trypanosoma cruzi epimastigote forms.
    Jorqueira A; Gouvêa RM; Ferreira VF; da Silva MN; de Souza MC; Zuma AA; Cavalcanti DF; Araújo HP; Santos DO; Bourguignon SC
    Parasitol Res; 2006 Sep; 99(4):429-33. PubMed ID: 16596415
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of the effect of methyl 2-acetamide-3-methylquinoxaline-7-carboxylate 1,4-di-N-oxide on the relative expression of the trypanothione reductase gene in Trypanosoma cruzi epimastigotes.
    Vazquez-Jimenez LKK; Hernandez-Posada MI; Paz-Gonzalez AD; Nogueda-Torres B; Martinez-Vazquez AV; Herrera-Mayorga V; Bocanegra-Garcia V; Rivera GR
    Pak J Pharm Sci; 2019 May; 32(3 Special):1447-1452. PubMed ID: 31551230
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal violet structural analogues identified by in silico drug repositioning present anti-Trypanosoma cruzi activity through inhibition of proline transporter TcAAAP069.
    Sayé M; Gauna L; Valera-Vera E; Reigada C; Miranda MR; Pereira CA
    PLoS Negl Trop Dis; 2020 Jan; 14(1):e0007481. PubMed ID: 31961864
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Introduction of changes in the DNA of Trypanosoma cruzi by trypanocidal agents].
    Goijman SG; Frasch AC; Stoppani AO
    Rev Argent Microbiol; 1984; 16(2):75-86. PubMed ID: 6400724
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Coumarins isolated from Calophyllum brasiliense produce ultrastructural alterations and affect in vitro infectivity of Trypanosoma cruzi.
    Rodríguez-Hernández KD; Martínez I; Agredano-Moreno LT; Jiménez-García LF; Reyes-Chilpa R; Espinoza B
    Phytomedicine; 2019 Aug; 61():152827. PubMed ID: 31039535
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.