These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 29410316)

  • 1. A Catalytically Disabled Double Mutant of Src Tyrosine Kinase Can Be Stabilized into an Active-Like Conformation.
    Meng Y; Ahuja LG; Kornev AP; Taylor SS; Roux B
    J Mol Biol; 2018 Mar; 430(6):881-889. PubMed ID: 29410316
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Computational study of the W260A activating mutant of Src tyrosine kinase.
    Meng Y; Roux B
    Protein Sci; 2016 Jan; 25(1):219-30. PubMed ID: 26106037
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tyrosine Kinase Activation and Conformational Flexibility: Lessons from Src-Family Tyrosine Kinases.
    Meng Y; Pond MP; Roux B
    Acc Chem Res; 2017 May; 50(5):1193-1201. PubMed ID: 28426203
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Locking the active conformation of c-Src kinase through the phosphorylation of the activation loop.
    Meng Y; Roux B
    J Mol Biol; 2014 Jan; 426(2):423-35. PubMed ID: 24103328
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hsp90 dependence of a kinase is determined by its conformational landscape.
    Luo Q; Boczek EE; Wang Q; Buchner J; Kaila VR
    Sci Rep; 2017 Mar; 7():43996. PubMed ID: 28290541
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conformational Transition of Key Structural Features Involved in Activation of ALK Induced by Two Neuroblastoma Mutations and ATP Binding: Insight from Accelerated Molecular Dynamics Simulations.
    He MY; Li WK; Zheng QC; Zhang HX
    ACS Chem Neurosci; 2018 Jul; 9(7):1783-1792. PubMed ID: 29638111
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conformation-selective inhibitors reveal differences in the activation and phosphate-binding loops of the tyrosine kinases Abl and Src.
    Hari SB; Perera BG; Ranjitkar P; Seeliger MA; Maly DJ
    ACS Chem Biol; 2013 Dec; 8(12):2734-43. PubMed ID: 24106839
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Network approach of the conformational change of c-Src, a tyrosine kinase, by molecular dynamics simulation.
    Yoon HJ; Lee S; Park SJ; Wu S
    Sci Rep; 2018 Apr; 8(1):5673. PubMed ID: 29618744
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mapping the conformational transition in Src activation by cumulating the information from multiple molecular dynamics trajectories.
    Yang S; Banavali NK; Roux B
    Proc Natl Acad Sci U S A; 2009 Mar; 106(10):3776-81. PubMed ID: 19225111
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An Allosteric Cross-Talk Between the Activation Loop and the ATP Binding Site Regulates the Activation of Src Kinase.
    Pucheta-Martínez E; Saladino G; Morando MA; Martinez-Torrecuadrada J; Lelli M; Sutto L; D'Amelio N; Gervasio FL
    Sci Rep; 2016 Apr; 6():24235. PubMed ID: 27063862
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A switch in nucleotide affinity governs activation of the Src and Tec family kinases.
    von Raußendorf F; de Ruiter A; Leonard TA
    Sci Rep; 2017 Dec; 7(1):17405. PubMed ID: 29234112
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-based network analysis of activation mechanisms in the ErbB family of receptor tyrosine kinases: the regulatory spine residues are global mediators of structural stability and allosteric interactions.
    James KA; Verkhivker GM
    PLoS One; 2014; 9(11):e113488. PubMed ID: 25427151
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Computational study of the "DFG-flip" conformational transition in c-Abl and c-Src tyrosine kinases.
    Meng Y; Lin YL; Roux B
    J Phys Chem B; 2015 Jan; 119(4):1443-56. PubMed ID: 25548962
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The αC-β4 loop controls the allosteric cooperativity between nucleotide and substrate in the catalytic subunit of protein kinase A.
    Olivieri C; Wang Y; Walker C; Subrahmanian MV; Ha KN; Bernlohr D; Gao J; Camilloni C; Vendruscolo M; Taylor SS; Veglia G
    Elife; 2024 Jun; 12():. PubMed ID: 38913408
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Activation of c-Src Tyrosine Kinase: Conformational Transition Pathway and Free Energy Landscape.
    Fajer M; Meng Y; Roux B
    J Phys Chem B; 2017 Apr; 121(15):3352-3363. PubMed ID: 27715044
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A dynamically coupled allosteric network underlies binding cooperativity in Src kinase.
    Foda ZH; Shan Y; Kim ET; Shaw DE; Seeliger MA
    Nat Commun; 2015 Jan; 6():5939. PubMed ID: 25600932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinase regulation by hydrophobic spine assembly in cancer.
    Hu J; Ahuja LG; Meharena HS; Kannan N; Kornev AP; Taylor SS; Shaw AS
    Mol Cell Biol; 2015 Jan; 35(1):264-76. PubMed ID: 25348715
    [TBL] [Abstract][Full Text] [Related]  

  • 18. How ATP-Competitive Inhibitors Allosterically Modulate Tyrosine Kinases That Contain a Src-like Regulatory Architecture.
    Fang L; Vilas-Boas J; Chakraborty S; Potter ZE; Register AC; Seeliger MA; Maly DJ
    ACS Chem Biol; 2020 Jul; 15(7):2005-2016. PubMed ID: 32479050
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Allosteric Modulation of Src Family Kinases with ATP-Competitive Inhibitors.
    Register AC; Chakraborty S; Maly DJ
    Methods Mol Biol; 2017; 1636():79-89. PubMed ID: 28730474
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Substrate-specific reorganization of the conformational ensemble of CSK implicates novel modes of kinase function.
    Jamros MA; Oliveira LC; Whitford PC; Onuchic JN; Adams JA; Jennings PA
    PLoS Comput Biol; 2012; 8(9):e1002695. PubMed ID: 23028292
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.