BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 29414793)

  • 1. High-throughput screen for inhibitors of protein-protein interactions in a reconstituted heat shock protein 70 (Hsp70) complex.
    Taylor IR; Dunyak BM; Komiyama T; Shao H; Ran X; Assimon VA; Kalyanaraman C; Rauch JN; Jacobson MP; Zuiderweg ERP; Gestwicki JE
    J Biol Chem; 2018 Mar; 293(11):4014-4025. PubMed ID: 29414793
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitors of difficult protein-protein interactions identified by high-throughput screening of multiprotein complexes.
    Cesa LC; Patury S; Komiyama T; Ahmad A; Zuiderweg ERP; Gestwicki JE
    ACS Chem Biol; 2013 Sep; 8(9):1988-1997. PubMed ID: 23819499
    [TBL] [Abstract][Full Text] [Related]  

  • 3. High-throughput screen for Escherichia coli heat shock protein 70 (Hsp70/DnaK): ATPase assay in low volume by exploiting energy transfer.
    Miyata Y; Chang L; Bainor A; McQuade TJ; Walczak CP; Zhang Y; Larsen MJ; Kirchhoff P; Gestwicki JE
    J Biomol Screen; 2010 Dec; 15(10):1211-9. PubMed ID: 20926844
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro.
    Rauch JN; Gestwicki JE
    J Biol Chem; 2014 Jan; 289(3):1402-14. PubMed ID: 24318877
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibitors and chemical probes for molecular chaperone networks.
    Gestwicki JE; Shao H
    J Biol Chem; 2019 Feb; 294(6):2151-2161. PubMed ID: 30213856
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chemical screens against a reconstituted multiprotein complex: myricetin blocks DnaJ regulation of DnaK through an allosteric mechanism.
    Chang L; Miyata Y; Ung PM; Bertelsen EB; McQuade TJ; Carlson HA; Zuiderweg ER; Gestwicki JE
    Chem Biol; 2011 Feb; 18(2):210-21. PubMed ID: 21338918
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An RNA aptamer specific to Hsp70-ATP conformation inhibits its ATPase activity independent of Hsp40.
    Thirunavukarasu D; Shi H
    Nucleic Acid Ther; 2015 Apr; 25(2):103-12. PubMed ID: 25654640
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hsp70 protein complexes as drug targets.
    Assimon VA; Gillies AT; Rauch JN; Gestwicki JE
    Curr Pharm Des; 2013; 19(3):404-17. PubMed ID: 22920901
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting Allosteric Control Mechanisms in Heat Shock Protein 70 (Hsp70).
    Li X; Shao H; Taylor IR; Gestwicki JE
    Curr Top Med Chem; 2016; 16(25):2729-40. PubMed ID: 27072701
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity.
    Fewell SW; Smith CM; Lyon MA; Dumitrescu TP; Wipf P; Day BW; Brodsky JL
    J Biol Chem; 2004 Dec; 279(49):51131-40. PubMed ID: 15448148
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human Hsp70 molecular chaperone binds two calcium ions within the ATPase domain.
    Sriram M; Osipiuk J; Freeman B; Morimoto R; Joachimiak A
    Structure; 1997 Mar; 5(3):403-14. PubMed ID: 9083109
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel inhibitors of heat shock protein Hsp70-mediated luciferase refolding that bind to DnaJ.
    Cassel JA; Ilyin S; McDonnell ME; Reitz AB
    Bioorg Med Chem; 2012 Jun; 20(11):3609-14. PubMed ID: 22546203
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery and Characterization of a Cryptic Secondary Binding Site in the Molecular Chaperone HSP70.
    O'Connor S; Le Bihan YV; Westwood IM; Liu M; Mak OW; Zazeri G; Povinelli APR; Jones AM; van Montfort R; Reynisson J; Collins I
    Molecules; 2022 Jan; 27(3):. PubMed ID: 35164081
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery.
    Pratt WB; Toft DO
    Exp Biol Med (Maywood); 2003 Feb; 228(2):111-33. PubMed ID: 12563018
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The novolactone natural product disrupts the allosteric regulation of Hsp70.
    Hassan AQ; Kirby CA; Zhou W; Schuhmann T; Kityk R; Kipp DR; Baird J; Chen J; Chen Y; Chung F; Hoepfner D; Movva NR; Pagliarini R; Petersen F; Quinn C; Quinn D; Riedl R; Schmitt EK; Schitter A; Stams T; Studer C; Fortin PD; Mayer MP; Sadlish H
    Chem Biol; 2015 Jan; 22(1):87-97. PubMed ID: 25544045
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The heat shock-binding protein (HspBP1) protects cells against the cytotoxic action of the Tag7-Hsp70 complex.
    Yashin DV; Dukhanina EA; Kabanova OD; Romanova EA; Lukyanova TI; Tonevitskii AG; Raynes DA; Gnuchev NV; Guerriero V; Georgiev GP; Sashchenko LP
    J Biol Chem; 2011 Mar; 286(12):10258-64. PubMed ID: 21247889
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Screening strategies to identify HSP70 modulators to treat Alzheimer's disease.
    Repalli J; Meruelo D
    Drug Des Devel Ther; 2015; 9():321-31. PubMed ID: 25609918
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthetic Small Molecule Modulators of Hsp70 and Hsp40 Chaperones as Promising Anticancer Agents.
    Nitzsche B; Höpfner M; Biersack B
    Int J Mol Sci; 2023 Feb; 24(4):. PubMed ID: 36835501
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of ATPase and chaperone cycle of DnaK from Thermus thermophilus by the nucleotide exchange factor GrpE.
    Groemping Y; Klostermeier D; Herrmann C; Veit T; Seidel R; Reinstein J
    J Mol Biol; 2001 Feb; 305(5):1173-83. PubMed ID: 11162122
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Trypanosoma cruzi heat shock protein 40 is able to stimulate the adenosine triphosphate hydrolysis activity of heat shock protein 70 and can substitute for a yeast heat shock protein 40.
    Edkins AL; Ludewig MH; Blatch GL
    Int J Biochem Cell Biol; 2004 Aug; 36(8):1585-98. PubMed ID: 15147737
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.