BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 29421568)

  • 21. 1-(2-((Z)-6-(2-(Trifluoromethyl)phenyl)hexa-3-en-1,5-diynyl)phenyl)piperidin-2-one as a new potent apoptosis agent.
    Tu YS; Duh TH; Tseng CY; Lin YT; Lo YH; Hu YL; Chen CH; Chien CM; Yang SH; Lin SR; Yang SC; Wu MJ
    Bioorg Med Chem; 2009 Nov; 17(21):7412-7. PubMed ID: 19818634
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Biological evaluation of 2-arylidene-4, 7-dimethyl indan-1-one (FXY-1): a novel Akt inhibitor with potent activity in lung cancer.
    Rajagopalan P; Alahmari KA; Elbessoumy AA; Balasubramaniam M; Suresh R; Shariff ME; Chandramoorthy HC
    Cancer Chemother Pharmacol; 2016 Feb; 77(2):393-404. PubMed ID: 26781309
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis, anticancer, and antibacterial activities of piplartine derivatives on cell cycle regulation and growth inhibition.
    Kumar JU; Shankaraiah G; Kumar RS; Pitke VV; Rao GT; Poornima B; Babu KS; Sreedhar AS
    J Asian Nat Prod Res; 2013; 15(6):658-69. PubMed ID: 23668860
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis, in vitro and in vivo evaluation of novel substituted N-(4-(2-(4-benzylpiperazin-1-yl)ethoxy)phenyl)-N-methyl-quinazolin-4-amines as potent antitumor agents.
    Cao D; Wang X; Lei L; Ma L; Wang F; Wang C; Tang M; Xiang W; Wang T; Li H; Chen L
    Bioorg Med Chem Lett; 2016 Apr; 26(8):1931-5. PubMed ID: 26979159
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Novel benzothiazine-piperazine derivatives by peptide-coupling as potential anti-proliferative agents.
    Venkatesh R; Kasaboina S; Bidayat D; Nikhil Kumar U; Jain N; Tangeda SJ; Bantu R; Janardhan S; Nagarapu L
    Bioorg Med Chem Lett; 2017 Jan; 27(2):354-359. PubMed ID: 27964883
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structure-cytotoxicity relationship in a series of N-phosphorus substituted E,E-3,5-bis(3-pyridinylmethylene)- and E,E-3,5-bis(4-pyridinylmethylene)piperid-4-ones.
    Leonova ES; Makarov MV; Rybalkina EY; Nayani SL; Tongwa P; Fonari A; Timofeeva TV; Odinets IL
    Eur J Med Chem; 2010 Dec; 45(12):5926-34. PubMed ID: 21035234
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis, crystal structures and anti-inflammatory activity of four 3,5-bis(arylidene)-N-benzenesulfonyl-4-piperidone derivatives.
    Li N; Bai X; Zhang L; Hou Y
    Acta Crystallogr C Struct Chem; 2018 Oct; 74(Pt 10):1171-1179. PubMed ID: 30284984
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis and biological evaluation of certain alpha,beta-unsaturated ketones and their corresponding fused pyridines as antiviral and cytotoxic agents.
    El-Subbagh HI; Abu-Zaid SM; Mahran MA; Badria FA; Al-Obaid AM
    J Med Chem; 2000 Jul; 43(15):2915-21. PubMed ID: 10956199
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis and biological evaluation of novel pyranochalcone derivatives as a new class of microtubule stabilizing agents.
    Cao D; Han X; Wang G; Yang Z; Peng F; Ma L; Zhang R; Ye H; Tang M; Wu W; Lei K; Wen J; Chen J; Qiu J; Liang X; Ran Y; Sang Y; Xiang M; Peng A; Chen L
    Eur J Med Chem; 2013 Apr; 62():579-89. PubMed ID: 23425970
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Evaluation of some N-acyl analogues of 3,5-bis(arylidene)-4-piperidones for cytotoxic activity.
    Dimmock JR; Arora VK; Duffy MJ; Reid RS; Allen TM; Kao GY
    Drug Des Discov; 1992 Jul; 8(4):291-9. PubMed ID: 1445994
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Synthesis, in vitro and in vivo evaluation of new hybrids of millepachine and phenstatin as potent tubulin polymerization inhibitors.
    An B; Zhang S; Yan J; Huang L; Li X
    Org Biomol Chem; 2017 Jan; 15(4):852-862. PubMed ID: 28009925
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design, synthesis, and biological evaluation of novel
    Xie X; Tu J; You H; Hu B
    Drug Des Devel Ther; 2017; 11():1439-1451. PubMed ID: 28553074
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Development of novel bis-pyrazole derivatives as antitumor agents with potent apoptosis induction effects and DNA damage.
    Dai H; Ge S; Guo J; Chen S; Huang M; Yang J; Sun S; Ling Y; Shi Y
    Eur J Med Chem; 2018 Jan; 143():1066-1076. PubMed ID: 29232583
    [TBL] [Abstract][Full Text] [Related]  

  • 34. 1-Phenyl-1H-indole derivatives as a new class of Bcl-2/Mcl-1 dual inhibitors: Design, synthesis, and preliminary biological evaluation.
    Xu G; Liu T; Zhou Y; Yang X; Fang H
    Bioorg Med Chem; 2017 Oct; 25(20):5548-5556. PubMed ID: 28866374
    [TBL] [Abstract][Full Text] [Related]  

  • 35. [Effects of CPUY013, a novel Topo I inhibitor, on human gastric adenocarcinoma BGC823 cells in vitro and in vivo].
    Ji YB; Zhou JH; Zuo MX; You QD
    Yao Xue Xue Bao; 2008 Aug; 43(8):811-8. PubMed ID: 18956773
    [TBL] [Abstract][Full Text] [Related]  

  • 36. [Effect of ZGDHu-1 on proliferation and apoptosis of A549 cells in vitro and antitumor activity in vivo].
    Zhou YL; Hu WX; Lü YP; Qiu LN; Wang WS; Yang ZY; Liu JD; Rao GW
    Yao Xue Xue Bao; 2007 Jan; 42(1):26-34. PubMed ID: 17520803
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A multi-scale systems pharmacology approach uncovers the anti-cancer molecular mechanism of Ixabepilone.
    Cao DS; Jiang SL; Guan YD; Chen XS; Zhang LX; Zhang Y; Chen AF; Yang JM; Cheng Y
    Eur J Med Chem; 2020 Aug; 199():112421. PubMed ID: 32428794
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis and anti-tumor activity of EF24 analogues as IKKβ inhibitors.
    Jin R; Chen Q; Yao S; Bai E; Fu W; Wang L; Wang J; Du X; Wei T; Xu H; Jiang C; Qiu P; Wu J; Li W; Liang G
    Eur J Med Chem; 2018 Jan; 144():218-228. PubMed ID: 29351887
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Synthesis and bioevaluation and doking study of 1H-pyrrolo[2,3-b]pyridine derivatives bearing aromatic hydrazone moiety as c-Met inhibitors.
    Wang W; Xu S; Duan Y; Liu X; Li X; Wang C; Zhao B; Zheng P; Zhu W
    Eur J Med Chem; 2018 Feb; 145():315-327. PubMed ID: 29331754
    [TBL] [Abstract][Full Text] [Related]  

  • 40. RL66 a second-generation curcumin analog has potent in vivo and in vitro anticancer activity in ER‑negative breast cancer models.
    Yadav B; Taurin S; Larsen L; Rosengren RJ
    Int J Oncol; 2012 Nov; 41(5):1723-32. PubMed ID: 22971638
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.