These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 29425683)

  • 1. Cynanbungeigenin C and D, a pair of novel epimers from Cynanchum bungei, suppress hedgehog pathway-dependent medulloblastoma by blocking signaling at the level of Gli.
    Li XY; Zhou LF; Gao LJ; Wei Y; Xu SF; Chen FY; Huang WJ; Tan WF; Ye YP
    Cancer Lett; 2018 Apr; 420():195-207. PubMed ID: 29425683
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of pseudolaric acid B as a novel Hedgehog pathway inhibitor in medulloblastoma.
    Wei SF; He DH; Zhang SB; Lu Y; Ye X; Fan XZ; Wang H; Wang Q; Liu YQ
    Biochem Pharmacol; 2021 Aug; 190():114593. PubMed ID: 33964282
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway.
    Chen J; Lv H; Hu J; Ji M; Xue N; Li C; Ma S; Zhou Q; Lin B; Li Y; Yu S; Chen X
    Cancer Lett; 2016 Oct; 381(2):391-403. PubMed ID: 27495899
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synergism between Hedgehog-GLI and EGFR signaling in Hedgehog-responsive human medulloblastoma cells induces downregulation of canonical Hedgehog-target genes and stabilized expression of GLI1.
    Götschel F; Berg D; Gruber W; Bender C; Eberl M; Friedel M; Sonntag J; Rüngeler E; Hache H; Wierling C; Nietfeld W; Lehrach H; Frischauf A; Schwartz-Albiez R; Aberger F; Korf U
    PLoS One; 2013; 8(6):e65403. PubMed ID: 23762360
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold.
    Berardozzi S; Bernardi F; Infante P; Ingallina C; Toscano S; De Paolis E; Alfonsi R; Caimano M; Botta B; Mori M; Di Marcotullio L; Ghirga F
    Eur J Med Chem; 2018 Aug; 156():554-562. PubMed ID: 30025349
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells.
    Scheidt T; Alka O; Gonczarowska-Jorge H; Gruber W; Rathje F; Dell'Aica M; Rurik M; Kohlbacher O; Zahedi RP; Aberger F; Huber CG
    Cell Commun Signal; 2020 Jun; 18(1):99. PubMed ID: 32576205
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via JNK-dependent but p53-independent mechanism.
    Azatyan A; Gallo-Oller G; Diao Y; Selivanova G; Johnsen JI; Zaphiropoulos PG
    Cancer Lett; 2019 Feb; 442():341-350. PubMed ID: 30447254
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system.
    Han Y; Xiong Y; Shi X; Wu J; Zhao Y; Jiang J
    PLoS Biol; 2017 Aug; 15(8):e2002063. PubMed ID: 28777795
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ABT-737 suppresses aberrant Hedgehog pathway and overcomes resistance to smoothened antagonists by blocking Gli.
    Huang W; Liu H; Tan W; Wang J
    Med Oncol; 2022 Sep; 39(12):188. PubMed ID: 36071246
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function.
    Lu J; Liu L; Zheng M; Li X; Wu A; Wu Q; Liao C; Zou J; Song H
    Oncogene; 2018 Jul; 37(28):3864-3878. PubMed ID: 29662197
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AT-101 inhibits hedgehog pathway activity and cancer growth.
    Wang J; Peng Y; Liu Y; Yang J; Huang M; Tan W
    Cancer Chemother Pharmacol; 2015 Sep; 76(3):461-9. PubMed ID: 26113054
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CBC-1 as a Cynanbungeigenin C derivative inhibits the growth of colorectal cancer through targeting Hedgehog pathway component GLI 1.
    Chen J; Chen W; Li X; Ye Y; Huang W; Gao L; Zhang M
    Steroids; 2024 Jun; 206():109421. PubMed ID: 38614233
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pyrvinium attenuates Hedgehog signaling downstream of smoothened.
    Li B; Fei DL; Flaveny CA; Dahmane N; Baubet V; Wang Z; Bai F; Pei XH; Rodriguez-Blanco J; Hang B; Orton D; Han L; Wang B; Capobianco AJ; Lee E; Robbins DJ
    Cancer Res; 2014 Sep; 74(17):4811-21. PubMed ID: 24994715
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MK-4101, a Potent Inhibitor of the Hedgehog Pathway, Is Highly Active against Medulloblastoma and Basal Cell Carcinoma.
    Filocamo G; Brunetti M; Colaceci F; Sasso R; Tanori M; Pasquali E; Alfonsi R; Mancuso M; Saran A; Lahm A; Di Marcotullio L; Steinkühler C; Pazzaglia S
    Mol Cancer Ther; 2016 Jun; 15(6):1177-89. PubMed ID: 26960983
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prostaglandin E1 Inhibits
    Wu F; Zhang C; Zhao C; Wu H; Teng Z; Jiang T; Wang Y
    Cancer Res; 2020 Jul; 80(13):2818-2832. PubMed ID: 32371475
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway.
    Beauchamp EM; Ringer L; Bulut G; Sajwan KP; Hall MD; Lee YC; Peaceman D; Ozdemirli M; Rodriguez O; Macdonald TJ; Albanese C; Toretsky JA; Uren A
    J Clin Invest; 2011 Jan; 121(1):148-60. PubMed ID: 21183792
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Saikosaponin B1 and Saikosaponin D inhibit tumor growth in medulloblastoma allograft mice via inhibiting the Hedgehog signaling pathway.
    Luo J; Wang J; Yang J; Huang W; Liu J; Tan W; Xin H
    J Nat Med; 2022 Jun; 76(3):584-593. PubMed ID: 35171398
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Statins Synergize with Hedgehog Pathway Inhibitors for Treatment of Medulloblastoma.
    Gordon RE; Zhang L; Peri S; Kuo YM; Du F; Egleston BL; Ng JMY; Andrews AJ; Astsaturov I; Curran T; Yang ZJ
    Clin Cancer Res; 2018 Mar; 24(6):1375-1388. PubMed ID: 29437795
    [No Abstract]   [Full Text] [Related]  

  • 19. Discovery of Novel Macrocyclic Hedgehog Pathway Inhibitors Acting by Suppressing the Gli-Mediated Transcription.
    Liu G; Huang W; Wang J; Liu X; Yang J; Zhang Y; Geng Y; Tan W; Zhang A
    J Med Chem; 2017 Oct; 60(19):8218-8245. PubMed ID: 28873303
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel-smoothened inhibitors for therapeutic targeting of naïve and drug-resistant hedgehog pathway-driven cancers.
    Li QR; Zhao H; Zhang XS; Lang H; Yu K
    Acta Pharmacol Sin; 2019 Feb; 40(2):257-267. PubMed ID: 29777201
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.