229 related articles for article (PubMed ID: 29425815)
1. Computer-aided insights into receptor-ligand interaction for novel 5-arylhydantoin derivatives as serotonin 5-HT
Kucwaj-Brysz K; Kurczab R; Jastrzębska-Więsek M; Żesławska E; Satała G; Nitek W; Partyka A; Siwek A; Jankowska A; Wesołowska A; Kieć-Kononowicz K; Handzlik J
Eur J Med Chem; 2018 Mar; 147():102-114. PubMed ID: 29425815
[TBL] [Abstract][Full Text] [Related]
2. Rational design in search for 5-phenylhydantoin selective 5-HT7R antagonists. Molecular modeling, synthesis and biological evaluation.
Kucwaj-Brysz K; Warszycki D; Podlewska S; Witek J; Witek K; González Izquierdo A; Satała G; Loza MI; Lubelska A; Latacz G; Bojarski AJ; Castro M; Kieć-Kononowicz K; Handzlik J
Eur J Med Chem; 2016 Apr; 112():258-269. PubMed ID: 26900658
[TBL] [Abstract][Full Text] [Related]
3. In the search for a lead structure among series of potent and selective hydantoin 5-HT
Latacz G; Lubelska A; Jastrzębska-Więsek M; Partyka A; Sobiło A; Olejarz A; Kucwaj-Brysz K; Satała G; Bojarski AJ; Wesołowska A; Kieć-Kononowicz K; Handzlik J
Chem Biol Drug Des; 2017 Dec; 90(6):1295-1306. PubMed ID: 28886235
[TBL] [Abstract][Full Text] [Related]
4. MF-8, a novel promising arylpiperazine-hydantoin based 5-HT
Latacz G; Lubelska A; Jastrzębska-Więsek M; Partyka A; Kucwaj-Brysz K; Wesołowska A; Kieć-Kononowicz K; Handzlik J
Bioorg Med Chem Lett; 2018 Mar; 28(5):878-883. PubMed ID: 29439902
[TBL] [Abstract][Full Text] [Related]
5. SAR-studies on the importance of aromatic ring topologies in search for selective 5-HT(7) receptor ligands among phenylpiperazine hydantoin derivatives.
Handzlik J; Bojarski AJ; Satała G; Kubacka M; Sadek B; Ashoor A; Siwek A; Więcek M; Kucwaj K; Filipek B; Kieć-Kononowicz K
Eur J Med Chem; 2014 May; 78():324-39. PubMed ID: 24691057
[TBL] [Abstract][Full Text] [Related]
6. Towards new 5-HT7 antagonists among arylsulfonamide derivatives of (aryloxy)ethyl-alkyl amines: Multiobjective based design, synthesis, and antidepressant and anxiolytic properties.
Canale V; Kurczab R; Partyka A; Satała G; Lenda T; Jastrzębska-Więsek M; Wesołowska A; Bojarski AJ; Zajdel P
Eur J Med Chem; 2016 Jan; 108():334-346. PubMed ID: 26698537
[TBL] [Abstract][Full Text] [Related]
7. Novel mannich bases, 5-arylimidazolidine-2,4-dione derivatives with dual 5-HT(1A) receptor and serotonin transporter affinity.
Czopek A; Kołaczkowski M; Bucki A; Byrtus H; Pawłowski M; Siwek A; Bojarski AJ; Bednarski M; Wróbel D; Wesołowska A
Arch Pharm (Weinheim); 2013 Feb; 346(2):98-109. PubMed ID: 23288448
[TBL] [Abstract][Full Text] [Related]
8. The computer-aided discovery of novel family of the 5-HT
Łażewska D; Kurczab R; Więcek M; Kamińska K; Satała G; Jastrzębska-Więsek M; Partyka A; Bojarski AJ; Wesołowska A; Kieć-Kononowicz K; Handzlik J
Eur J Med Chem; 2017 Jul; 135():117-124. PubMed ID: 28441580
[TBL] [Abstract][Full Text] [Related]
9. Novel N-acyl-carbazole derivatives as 5-HT7R antagonists.
Kim Y; Yeom M; Tae J; Rhim H; Choo H
Eur J Med Chem; 2016 Mar; 110():302-10. PubMed ID: 26852005
[TBL] [Abstract][Full Text] [Related]
10. The role of aryl-topology in balancing between selective and dual 5-HT
Kucwaj-Brysz K; Kurczab R; Żesławska E; Lubelska A; Marć MA; Latacz G; Satała G; Nitek W; Kieć-Kononowicz K; Handzlik J
Medchemcomm; 2018 Jun; 9(6):1033-1044. PubMed ID: 30108992
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and computer-aided SAR studies for derivatives of phenoxyalkyl-1,3,5-triazine as the new potent ligands for serotonin receptors 5-HT
Ali W; Więcek M; Łażewska D; Kurczab R; Jastrzębska-Więsek M; Satała G; Kucwaj-Brysz K; Lubelska A; Głuch-Lutwin M; Mordyl B; Siwek A; Nasim MJ; Partyka A; Sudoł S; Latacz G; Wesołowska A; Kieć-Kononowicz K; Handzlik J
Eur J Med Chem; 2019 Sep; 178():740-751. PubMed ID: 31229876
[TBL] [Abstract][Full Text] [Related]
12. New 8-aminoalkyl derivatives of purine-2,6-dione with arylalkyl, allyl or propynyl substituents in position 7, their 5-HT1A, 5-HT2A, and 5-HT7 receptor affinity and pharmacological evaluation.
Chłoń-Rzepa G; Zmudzki P; Satała G; Duszyńska B; Partyka A; Wróbel D; Jastrzębska-Więsek M; Wesołowska A; Bojarski AJ; Pawłowski M; Zajdel P
Pharmacol Rep; 2013; 65(1):15-29. PubMed ID: 23563020
[TBL] [Abstract][Full Text] [Related]
13. Computer-Aided Studies for Novel Arylhydantoin 1,3,5-Triazine Derivatives as 5-HT₆ Serotonin Receptor Ligands with Antidepressive-Like, Anxiolytic and Antiobesity Action In Vivo.
Kurczab R; Ali W; Łażewska D; Kotańska M; Jastrzębska-Więsek M; Satała G; Więcek M; Lubelska A; Latacz G; Partyka A; Starek M; Dąbrowska M; Wesołowska A; Jacob C; Kieć-Kononowicz K; Handzlik J
Molecules; 2018 Oct; 23(10):. PubMed ID: 30282913
[TBL] [Abstract][Full Text] [Related]
14. The extracellular entrance provides selectivity to serotonin 5-HT7 receptor antagonists with antidepressant-like behavior in vivo.
Medina RA; Vázquez-Villa H; Gómez-Tamayo JC; Benhamú B; Martín-Fontecha M; de la Fuente T; Caltabiano G; Hedlund PB; Pardo L; López-Rodríguez ML
J Med Chem; 2014 Aug; 57(15):6879-84. PubMed ID: 25073094
[TBL] [Abstract][Full Text] [Related]
15. The relationship between stereochemical and both, pharmacological and ADME-Tox, properties of the potent hydantoin 5-HT
Kucwaj-Brysz K; Latacz G; Podlewska S; Żesławska E; Handzlik J; Lubelska A; Satała G; Nitek W; Handzlik J
Bioorg Chem; 2021 Jan; 106():104466. PubMed ID: 33246603
[TBL] [Abstract][Full Text] [Related]
16. New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263.
Ofori E; Onyameh EK; Gonela UM; Voshavar C; Bricker B; Swanson TL; Eshleman AJ; Schmachtenberg JL; Bloom SH; Janowsky AJ; Ablordeppey SY
Eur J Med Chem; 2021 Mar; 214():113243. PubMed ID: 33582388
[TBL] [Abstract][Full Text] [Related]
17. Pharmacophore models based studies on the affinity and selectivity toward 5-HT1A with reference to α1-adrenergic receptors among arylpiperazine derivatives of phenytoin.
Handzlik J; Szymańska E; Nędza K; Kubacka M; Siwek A; Mogilski S; Handzlik J; Filipek B; Kieć-Kononowicz K
Bioorg Med Chem; 2011 Feb; 19(3):1349-60. PubMed ID: 21232965
[TBL] [Abstract][Full Text] [Related]
18. Design and synthesis of new homo and hetero bis-piperazinyl-1-propanone derivatives as 5-HT7R selective ligands over 5-HT1AR.
Intagliata S; Modica MN; Pittalà V; Salerno L; Siracusa MA; Cagnotto A; Salmona M; Romeo G
Bioorg Med Chem Lett; 2016 Aug; 26(16):4052-6. PubMed ID: 27396505
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of 2-fluoro and 3-trifluoromethyl-phenyl-piperazinylalkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione as potential antidepressant agents.
Zagórska A; Bucki A; Kołaczkowski M; Siwek A; Głuch-Lutwin M; Starowicz G; Kazek G; Partyka A; Wesołowska A; Słoczyńska K; Pękala E; Pawłowski M
J Enzyme Inhib Med Chem; 2016; 31(sup3):10-24. PubMed ID: 27353547
[TBL] [Abstract][Full Text] [Related]
20. NEW SPIROHYDANTOIN DERIVATIVES - SYNTHESIS, PHARMACOLOGICAL EVALUATION, AND MOLECULAR MODELING STUDY.
Czopek A; Zagorska A; Kolaczkowski M; Bucki A; Gryzlo B; Rychtyk J; Pawlowsk M; Siwek A; Satala G; Bojarski A; Kubacka M; Filipek B
Acta Pol Pharm; 2016 Nov; 73(6):1545-1554. PubMed ID: 29634109
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
