BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 29427592)

  • 1. Establishment of engineered cell-based assays mediating LAG3 and PD1 immune suppression enables potency measurement of blocking antibodies and assessment of signal transduction.
    Bhagwat B; Cherwinski H; Sathe M; Seghezzi W; McClanahan TK; de Waal Malefyt R; Willingham A
    J Immunol Methods; 2018 May; 456():7-14. PubMed ID: 29427592
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Investigating combination benefit of PD1 and LAG3 co-blockade using an engineered cellular bioassay.
    Bhagwat B; de Waal Malefyt R; Willingham A
    Int Immunopharmacol; 2023 Jun; 119():109566. PubMed ID: 37044037
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LAG3 and PD1 Regulate CD8+ T Cell in Diffuse Large B-cell Lymphoma Patients.
    Liu Y; Guo X; Zhan L; Wang L; Wang X; Jiang M
    Comput Math Methods Med; 2021; 2021():4468140. PubMed ID: 34422089
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LAG3 (CD223) as a cancer immunotherapy target.
    Andrews LP; Marciscano AE; Drake CG; Vignali DA
    Immunol Rev; 2017 Mar; 276(1):80-96. PubMed ID: 28258692
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas.
    Zhou G; Sprengers D; Boor PPC; Doukas M; Schutz H; Mancham S; Pedroza-Gonzalez A; Polak WG; de Jonge J; Gaspersz M; Dong H; Thielemans K; Pan Q; IJzermans JNM; Bruno MJ; Kwekkeboom J
    Gastroenterology; 2017 Oct; 153(4):1107-1119.e10. PubMed ID: 28648905
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The multi-specific V
    Edwards CJ; Sette A; Cox C; Di Fiore B; Wyre C; Sydoruk D; Yadin D; Hayes P; Stelter S; Bartlett PD; Zuazo M; Garcia-Granda MJ; Benedetti G; Fiaska S; Birkett NR; Teng Y; Enever C; Arasanz H; Bocanegra A; Chocarro L; Fernandez G; Vera R; Archer B; Osuch I; Lewandowska M; Surani YM; Kochan G; Escors D; Legg J; Pierce AJ
    Br J Cancer; 2022 May; 126(8):1168-1177. PubMed ID: 34969998
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Association Between Expression Level of PD1 by Tumor-Infiltrating CD8
    Kim HD; Song GW; Park S; Jung MK; Kim MH; Kang HJ; Yoo C; Yi K; Kim KH; Eo S; Moon DB; Hong SM; Ju YS; Shin EC; Hwang S; Park SH
    Gastroenterology; 2018 Dec; 155(6):1936-1950.e17. PubMed ID: 30145359
    [TBL] [Abstract][Full Text] [Related]  

  • 8. LAG3 and PD1 co-inhibitory molecules collaborate to limit CD8+ T cell signaling and dampen antitumor immunity in a murine ovarian cancer model.
    Huang RY; Eppolito C; Lele S; Shrikant P; Matsuzaki J; Odunsi K
    Oncotarget; 2015 Sep; 6(29):27359-77. PubMed ID: 26318293
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lymphocyte activation gene 3: a novel therapeutic target in chronic lymphocytic leukemia.
    Shapiro M; Herishanu Y; Katz BZ; Dezorella N; Sun C; Kay S; Polliack A; Avivi I; Wiestner A; Perry C
    Haematologica; 2017 May; 102(5):874-882. PubMed ID: 28154084
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiplex Immuno-Liquid Chromatography-Mass Spectrometry-Parallel Reaction Monitoring (LC-MS-PRM) Quantitation of CD8A, CD4, LAG3, PD1, PD-L1, and PD-L2 in Frozen Human Tissues.
    Zhang Q; Salzler R; Dore A; Yang J; Ma D; Olson WC; Liu Y
    J Proteome Res; 2018 Nov; 17(11):3932-3940. PubMed ID: 30277784
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding.
    Andrews LP; Somasundaram A; Moskovitz JM; Szymczak-Workman AL; Liu C; Cillo AR; Lin H; Normolle DP; Moynihan KD; Taniuchi I; Irvine DJ; Kirkwood JM; Lipson EJ; Ferris RL; Bruno TC; Workman CJ; Vignali DAA
    Sci Immunol; 2020 Jul; 5(49):. PubMed ID: 32680952
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors.
    Natoli M; Hatje K; Gulati P; Junker F; Herzig P; Jiang Z; Davydov II; Germann M; Trüb M; Marbach D; Zwick A; Weber P; Seeber S; Wiese M; Lardinois D; Heinzelmann-Schwarz V; Rosenberg R; Tietze L; Mertz KD; Umaña P; Klein C; Codarri-Deak L; Kao H; Zippelius A
    J Immunother Cancer; 2022 Nov; 10(11):. PubMed ID: 36319064
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Roles, function and relevance of LAG3 in HIV infection.
    Graydon CG; Balasko AL; Fowke KR
    PLoS Pathog; 2019 Jan; 15(1):e1007429. PubMed ID: 30653605
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sym021, a promising anti-PD1 clinical candidate antibody derived from a new chicken antibody discovery platform.
    Gjetting T; Gad M; Fröhlich C; Lindsted T; Melander MC; Bhatia VK; Grandal MM; Dietrich N; Uhlenbrock F; Galler GR; Strandh M; Lantto J; Bouquin T; Horak ID; Kragh M; Pedersen MW; Koefoed K
    MAbs; 2019; 11(4):666-680. PubMed ID: 31046547
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular and Clinical Characterization of LAG3 in Breast Cancer Through 2994 Samples.
    Liu Q; Qi Y; Zhai J; Kong X; Wang X; Wang Z; Fang Y; Wang J
    Front Immunol; 2021; 12():599207. PubMed ID: 34267742
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The co-expression characteristics of LAG3 and PD-1 on the T cells of patients with breast cancer reveal a new therapeutic strategy.
    Du H; Yi Z; Wang L; Li Z; Niu B; Ren G
    Int Immunopharmacol; 2020 Jan; 78():106113. PubMed ID: 31841754
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lymphocyte-activation gene 3 (LAG3): The next immune checkpoint receptor.
    Ruffo E; Wu RC; Bruno TC; Workman CJ; Vignali DAA
    Semin Immunol; 2019 Apr; 42():101305. PubMed ID: 31604537
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Different Expression Characteristics of LAG3 and PD-1 in Sepsis and Their Synergistic Effect on T Cell Exhaustion: A New Strategy for Immune Checkpoint Blockade.
    Niu B; Zhou F; Su Y; Wang L; Xu Y; Yi Z; Wu Y; Du H; Ren G
    Front Immunol; 2019; 10():1888. PubMed ID: 31440257
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An optimized protocol for the in vitro generation and functional analysis of human PD1/PD-L1 signal.
    Khedri M; Abnous K; Rafatpanah H; Ramezani M
    J Recept Signal Transduct Res; 2018 Feb; 38(1):31-36. PubMed ID: 29252078
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular Pathways and Mechanisms of LAG3 in Cancer Therapy.
    Andrews LP; Cillo AR; Karapetyan L; Kirkwood JM; Workman CJ; Vignali DAA
    Clin Cancer Res; 2022 Dec; 28(23):5030-5039. PubMed ID: 35579997
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.