BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

100 related articles for article (PubMed ID: 29428525)

  • 1. Synthesis and activity evaluation of a series of cholanamides as modulators of the liver X receptors.
    Martínez MD; Ghini AA; Dansey MV; Veleiro AS; Pecci A; Alvarez LD; Burton G
    Bioorg Med Chem; 2018 Mar; 26(5):1092-1101. PubMed ID: 29428525
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In search for novel liver X receptors modulators by extending the structure-activity relationships of cholenamide derivatives.
    Pontini L; Palazzoli P; Maggioni D; Damiano G; Giorgi G; Russo V; Marinozzi M
    Chem Phys Lipids; 2021 Nov; 241():105151. PubMed ID: 34673009
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fluorinated oxysterol analogues: Synthesis, molecular modelling and LXRβ activity.
    Rodriguez CR; Alvarez LD; Dansey MV; Paolo LS; Veleiro AS; Pecci A; Burton G
    J Steroid Biochem Mol Biol; 2017 Jan; 165(Pt B):268-276. PubMed ID: 27452335
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthetic LXR agonist suppresses endogenous cholesterol biosynthesis and efficiently lowers plasma cholesterol.
    Pfeifer T; Buchebner M; Chandak PG; Patankar J; Kratzer A; Obrowsky S; Rechberger GN; Kadam RS; Kompella UB; Kostner GM; Kratky D; Levak-Frank S
    Curr Pharm Biotechnol; 2011 Feb; 12(2):285-92. PubMed ID: 21190543
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selective LXR agonist DMHCA corrects retinal and bone marrow dysfunction in type 2 diabetes.
    Vieira CP; Fortmann SD; Hossain M; Longhini AL; Hammer SS; Asare-Bediako B; Crossman DK; Sielski MS; Adu-Agyeiwaah Y; Dupont M; Floyd JL; Li Calzi S; Lydic T; Welner RS; Blanchard GJ; Busik JV; Grant MB
    JCI Insight; 2020 Jul; 5(13):. PubMed ID: 32641586
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype.
    Lund EG; Peterson LB; Adams AD; Lam MH; Burton CA; Chin J; Guo Q; Huang S; Latham M; Lopez JC; Menke JG; Milot DP; Mitnaul LJ; Rex-Rabe SE; Rosa RL; Tian JY; Wright SD; Sparrow CP
    Biochem Pharmacol; 2006 Feb; 71(4):453-63. PubMed ID: 16325781
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of Tetrachlorophthalimides as Liver X Receptor β (LXRβ)-Selective Agonists.
    Nomura S; Endo-Umeda K; Makishima M; Hashimoto Y; Ishikawa M
    ChemMedChem; 2016 Oct; 11(20):2347-2360. PubMed ID: 27690261
    [TBL] [Abstract][Full Text] [Related]  

  • 8. C24-hydroxylated stigmastane derivatives as Liver X Receptor agonists.
    Castro Navas FF; Giorgi G; Maggioni D; Pacciarini M; Russo V; Marinozzi M
    Chem Phys Lipids; 2018 May; 212():44-50. PubMed ID: 29352964
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cholestenoic acid analogues as inverse agonists of the liver X receptors.
    Alvarez LD; Dansey MV; Ogara MF; Peña CI; Houtman R; Veleiro AS; Pecci A; Burton G
    J Steroid Biochem Mol Biol; 2020 May; 199():105585. PubMed ID: 31931135
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structurally Selective Mechanism of Liver X Receptor Ligand:
    Ding P; Chen Z; Chen H; Zhang Z; Liu Z; Yan X; Zhou H; Gu Q; Li C; Xu J
    J Chem Inf Model; 2019 Jul; 59(7):3277-3290. PubMed ID: 31192592
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting.
    Quinet EM; Savio DA; Halpern AR; Chen L; Schuster GU; Gustafsson JA; Basso MD; Nambi P
    Mol Pharmacol; 2006 Oct; 70(4):1340-9. PubMed ID: 16825483
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-based virtual screening for identification of potential non-steroidal LXR modulators against neurodegenerative conditions.
    Deshwal S; Baidya AT; Kumar R; Sandhir R
    J Steroid Biochem Mol Biol; 2022 Oct; 223():106150. PubMed ID: 35787453
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Liver X Receptors and their Agonists: Targeting for Cholesterol Homeostasis and Cardiovascular Diseases.
    Ma Z; Deng C; Hu W; Zhou J; Fan C; Di S; Liu D; Yang Y; Wang D
    Curr Issues Mol Biol; 2017; 22():41-64. PubMed ID: 27669666
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Liver X receptors interact with corepressors to regulate gene expression.
    Hu X; Li S; Wu J; Xia C; Lala DS
    Mol Endocrinol; 2003 Jun; 17(6):1019-26. PubMed ID: 12663743
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyanidin, a natural flavonoid, is an agonistic ligand for liver X receptor alpha and beta and reduces cellular lipid accumulation in macrophages and hepatocytes.
    Jia Y; Hoang MH; Jun HJ; Lee JH; Lee SJ
    Bioorg Med Chem Lett; 2013 Jul; 23(14):4185-90. PubMed ID: 23769638
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identfication of Potent LXRβ-Selective Agonists without LXRα Activation by In Silico Approaches.
    Chen M; Yang F; Kang J; Gan H; Yang X; Lai X; Gao Y
    Molecules; 2018 Jun; 23(6):. PubMed ID: 29867043
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Destabilization of the torsioned conformation of a ligand side chain inverts the LXRβ activity.
    Álvarez LD; Dansey MV; Grinman DY; Navalesi D; Samaja GA; Del Fueyo MC; Bastiaensen N; Houtman R; Estrin DA; Veleiro AS; Pecci A; Burton G
    Biochim Biophys Acta; 2015 Dec; 1851(12):1577-86. PubMed ID: 26434697
    [TBL] [Abstract][Full Text] [Related]  

  • 18.
    El-Darzi N; Astafev A; Mast N; Saadane A; Lam M; Pikuleva IA
    Front Pharmacol; 2018; 9():827. PubMed ID: 30090064
    [No Abstract]   [Full Text] [Related]  

  • 19. Recent Advances in the Medicinal Chemistry of Liver X Receptors.
    El-Gendy BEM; Goher SS; Hegazy LS; Arief MMH; Burris TP
    J Med Chem; 2018 Dec; 61(24):10935-10956. PubMed ID: 30004226
    [TBL] [Abstract][Full Text] [Related]  

  • 20. LXRβ activation increases intestinal cholesterol absorption, leading to an atherogenic lipoprotein profile.
    Hu X; Steffensen KR; Jiang ZY; Parini P; Gustafsson JÅ; Gåfvels M; Eggertsen G
    J Intern Med; 2012 Nov; 272(5):452-64. PubMed ID: 22329358
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.