BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

820 related articles for article (PubMed ID: 29430620)

  • 1. Herp Promotes Degradation of Mutant Huntingtin: Involvement of the Proteasome and Molecular Chaperones.
    Luo H; Cao L; Liang X; Du A; Peng T; Li H
    Mol Neurobiol; 2018 Oct; 55(10):7652-7668. PubMed ID: 29430620
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Atypical ubiquitination by E3 ligase WWP1 inhibits the proteasome-mediated degradation of mutant huntingtin.
    Lin L; Jin Z; Tan H; Xu Q; Peng T; Li H
    Brain Res; 2016 Jul; 1643():103-12. PubMed ID: 27107943
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ubiquitin ligase Hrd1 enhances the degradation and suppresses the toxicity of polyglutamine-expanded huntingtin.
    Yang H; Zhong X; Ballar P; Luo S; Shen Y; Rubinsztein DC; Monteiro MJ; Fang S
    Exp Cell Res; 2007 Feb; 313(3):538-50. PubMed ID: 17141218
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of p38 Mitogen-Activated Protein Kinase Ameliorates HAP40 Depletion-Induced Toxicity and Proteasomal Defect in Huntington's Disease Model.
    Huang ZN; Chen JM; Huang LC; Fang YH; Her LS
    Mol Neurobiol; 2021 Jun; 58(6):2704-2723. PubMed ID: 33492644
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Homocysteine-induced endoplasmic reticulum protein (Herp) is up-regulated in sporadic inclusion-body myositis and in endoplasmic reticulum stress-induced cultured human muscle fibers.
    Nogalska A; Engel WK; McFerrin J; Kokame K; Komano H; Askanas V
    J Neurochem; 2006 Mar; 96(5):1491-9. PubMed ID: 16441512
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An E3 Ubiquitin Ligase, Synoviolin, Is Involved in the Degradation of Homocysteine-Inducible Endoplasmic Reticulum Protein.
    Maeda T; Fujita Y; Tanabe-Fujimura C; Zou K; Liu J; Liu S; Kikuchi K; Shen X; Nakajima T; Komano H
    Biol Pharm Bull; 2018; 41(6):915-919. PubMed ID: 29863080
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins.
    Reijonen S; Putkonen N; Nørremølle A; Lindholm D; Korhonen L
    Exp Cell Res; 2008 Mar; 314(5):950-60. PubMed ID: 18255062
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sigma-1 receptor is involved in degradation of intranuclear inclusions in a cellular model of Huntington's disease.
    Miki Y; Tanji K; Mori F; Wakabayashi K
    Neurobiol Dis; 2015 Feb; 74():25-31. PubMed ID: 25449906
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The dynamics of early-state transcriptional changes and aggregate formation in a Huntington's disease cell model.
    van Hagen M; Piebes DGE; de Leeuw WC; Vuist IM; van Roon-Mom WMC; Moerland PD; Verschure PJ
    BMC Genomics; 2017 May; 18(1):373. PubMed ID: 28499347
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Polyglutamine tracts regulate beclin 1-dependent autophagy.
    Ashkenazi A; Bento CF; Ricketts T; Vicinanza M; Siddiqi F; Pavel M; Squitieri F; Hardenberg MC; Imarisio S; Menzies FM; Rubinsztein DC
    Nature; 2017 May; 545(7652):108-111. PubMed ID: 28445460
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects.
    Hakim-Eshed V; Boulos A; Cohen-Rosenzweig C; Yu-Taeger L; Ziv T; Kwon YT; Riess O; Phuc Nguyen HH; Ziv NE; Ciechanover A
    Proc Natl Acad Sci U S A; 2020 Aug; 117(31):18661-18669. PubMed ID: 32675242
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ENC1 Modulates the Aggregation and Neurotoxicity of Mutant Huntingtin Through p62 Under ER Stress.
    Lee H; Ahn HH; Lee W; Oh Y; Choi H; Shim SM; Shin J; Jung YK
    Mol Neurobiol; 2016 Dec; 53(10):6620-6634. PubMed ID: 26637326
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1α.
    Hyrskyluoto A; Bruelle C; Lundh SH; Do HT; Kivinen J; Rappou E; Reijonen S; Waltimo T; Petersén Å; Lindholm D; Korhonen L
    Hum Mol Genet; 2014 Nov; 23(22):5928-39. PubMed ID: 24951540
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteostasis of Huntingtin in Health and Disease.
    Koyuncu S; Fatima A; Gutierrez-Garcia R; Vilchez D
    Int J Mol Sci; 2017 Jul; 18(7):. PubMed ID: 28753941
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MnFe
    Zhang L; Wei PF; Song YH; Dong L; Wu YD; Hao ZY; Fan S; Tai S; Meng JL; Lu Y; Xue J; Liang CZ; Wen LP
    Biomaterials; 2019 Sep; 216():119248. PubMed ID: 31226569
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NAD(P)H quinone oxidoreductase 1 inhibits the proteasomal degradation of homocysteine-induced endoplasmic reticulum protein.
    Maeda T; Tanabe-Fujimura C; Fujita Y; Abe C; Nanakida Y; Zou K; Liu J; Liu S; Nakajima T; Komano H
    Biochem Biophys Res Commun; 2016 May; 473(4):1276-1280. PubMed ID: 27084451
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal Processes.
    Zhao T; Hong Y; Li S; Li XJ
    J Neurosci; 2016 Aug; 36(32):8317-28. PubMed ID: 27511006
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Degradation of mutant huntingtin via the ubiquitin/proteasome system is modulated by FE65.
    Chow WN; Luk HW; Chan HY; Lau KF
    Biochem J; 2012 May; 443(3):681-9. PubMed ID: 22352297
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Cytotoxicity and Clearance of Mutant Huntingtin and Other Misfolded Proteins.
    Folger A; Wang Y
    Cells; 2021 Oct; 10(11):. PubMed ID: 34831058
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
    Yue HW; Hong JY; Zhang SX; Jiang LL; Hu HY
    Sci Rep; 2021 Apr; 11(1):7815. PubMed ID: 33837238
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.