BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 29433143)

  • 21. 1,3-Thiazole Derivatives as a Promising Scaffold in Medicinal Chemistry: A Recent Overview.
    Kushwaha P; Pandey S
    Antiinflamm Antiallergy Agents Med Chem; 2023; 22(3):133-163. PubMed ID: 37997807
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.
    Musumeci F; Sanna M; Greco C; Giacchello I; Fallacara AL; Amato R; Schenone S
    Expert Opin Ther Pat; 2017 Dec; 27(12):1305-1318. PubMed ID: 28705083
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Pyrrolopyrimidine derivatives and purine analogs as novel activators of Multidrug Resistance-associated Protein 1 (MRP1, ABCC1).
    Schmitt SM; Stefan K; Wiese M
    Biochim Biophys Acta Biomembr; 2017 Jan; 1859(1):69-79. PubMed ID: 27810353
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Identification of 5,6-substituted 4-aminothieno[2,3-d]pyrimidines as LIMK1 inhibitors.
    Sleebs BE; Nikolakopoulos G; Street IP; Falk H; Baell JB
    Bioorg Med Chem Lett; 2011 Oct; 21(19):5992-4. PubMed ID: 21852129
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and Evaluation of Cytotoxic Activity of Some Pyrroles and Fused Pyrroles.
    Fatahala SS; Mohamed MS; Youns M; Abd-El Hameed RH
    Anticancer Agents Med Chem; 2017; 17(7):1014-1025. PubMed ID: 28042776
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Effects of pyrrolopyrimidine derivatives on cancer cells cultured in vitro and potential mechanism.
    Kilic-Kurt Z; Celik A; Bakar-Ates F
    Naunyn Schmiedebergs Arch Pharmacol; 2024 May; 397(5):3169-3177. PubMed ID: 37891256
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The discovery of 2,5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 2 (JAK2) inhibitors versus JAK1 and JAK3.
    Lee SM; Yoon KB; Lee HJ; Kim J; Chung YK; Cho WJ; Mukai C; Choi S; Kang KW; Han SY; Ko H; Kim YC
    Bioorg Med Chem; 2016 Nov; 24(21):5036-5046. PubMed ID: 27555284
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Design, Synthesis, and Biological Evaluation of Substituted Pyrimidines as Potential Phosphatidylinositol 3-Kinase (PI3K) Inhibitors.
    Zhang JQ; Luo YJ; Xiong YS; Yu Y; Tu ZC; Long ZJ; Lai XJ; Chen HX; Luo Y; Weng J; Lu G
    J Med Chem; 2016 Aug; 59(15):7268-74. PubMed ID: 27427973
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Design, synthesis and evaluation of novel diaryl pyrrolopyrimidine and pyrrolothiazine derivatives as inhibitors of tumor necrosis factor stimulated gene-14 (TSG-14) production.
    Hilmy KM; Soliman DH; Shahin EB; El-Deeb HS; El-Kousy SM
    Eur J Med Chem; 2014 May; 78():419-24. PubMed ID: 24704614
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Pyrrolopyrimidine-inhibitors with hydantoin moiety as spacer can explore P4/S4 interaction on plasmin.
    Teno N; Gohda K; Wanaka K; Tsuda Y; Sueda T; Yamashita Y; Otsubo T
    Bioorg Med Chem; 2014 Apr; 22(7):2339-52. PubMed ID: 24613052
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Pyrrole-3-carboxamides as potent and selective JAK2 inhibitors.
    Brasca MG; Nesi M; Avanzi N; Ballinari D; Bandiera T; Bertrand J; Bindi S; Canevari G; Carenzi D; Casero D; Ceriani L; Ciomei M; Cirla A; Colombo M; Cribioli S; Cristiani C; Della Vedova F; Fachin G; Fasolini M; Felder ER; Galvani A; Isacchi A; Mirizzi D; Motto I; Panzeri A; Pesenti E; Vianello P; Gnocchi P; Donati D
    Bioorg Med Chem; 2014 Sep; 22(17):4998-5012. PubMed ID: 25009002
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Synthesis, and docking studies of phenylpyrimidine-carboxamide derivatives bearing 1H-pyrrolo[2,3-b]pyridine moiety as c-Met inhibitors.
    Zhu W; Wang W; Xu S; Wang J; Tang Q; Wu C; Zhao Y; Zheng P
    Bioorg Med Chem; 2016 Apr; 24(8):1749-56. PubMed ID: 26964675
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Novel antiviral compounds against gastroenteric viral infections.
    Mohamed MS; Abd El-Hameed RH; Sayed AI; Soror SH
    Arch Pharm (Weinheim); 2015 Mar; 348(3):194-205. PubMed ID: 25704120
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design and synthesis of thienopyrimidine urea derivatives with potential cytotoxic and pro-apoptotic activity against breast cancer cell line MCF-7.
    Abdelhaleem EF; Abdelhameid MK; Kassab AE; Kandeel MM
    Eur J Med Chem; 2018 Jan; 143():1807-1825. PubMed ID: 29133058
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Pyrrolizines: Promising scaffolds for anticancer drugs.
    Belal A; El-Gendy Bel-D
    Bioorg Med Chem; 2014 Jan; 22(1):46-53. PubMed ID: 24331756
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Discovery of 4-(Piperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine Derivatives as Akt Inhibitors.
    Liu Y; Yin Y; Zhang J; Nomie K; Zhang L; Yang D; Wang ML; Zhao G
    Arch Pharm (Weinheim); 2016 May; 349(5):356-62. PubMed ID: 26991997
    [TBL] [Abstract][Full Text] [Related]  

  • 37. In vitro baselining of new pyrrolopyrimidine EGFR-TK inhibitors with Erlotinib.
    Sundby E; Han J; Kaspersen SJ; Hoff BH
    Eur J Pharm Sci; 2015 Dec; 80():56-65. PubMed ID: 26296860
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Novel dual Src/Abl inhibitors for hematologic and solid malignancies.
    Schenone S; Brullo C; Musumeci F; Botta M
    Expert Opin Investig Drugs; 2010 Aug; 19(8):931-45. PubMed ID: 20557276
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.
    Tari LW; Trzoss M; Bensen DC; Li X; Chen Z; Lam T; Zhang J; Creighton CJ; Cunningham ML; Kwan B; Stidham M; Shaw KJ; Lightstone FC; Wong SE; Nguyen TB; Nix J; Finn J
    Bioorg Med Chem Lett; 2013 Mar; 23(5):1529-36. PubMed ID: 23352267
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors.
    Zhao Y; Zhang J; Zhuang R; He R; Xi J; Pan X; Shao Y; Pan J; Sun J; Cai Z; Liu S; Huang W; Lv X
    Bioorg Med Chem; 2017 Jun; 25(12):3195-3205. PubMed ID: 28412159
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.