BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 29435052)

  • 1. Simvastatin in combination with meclofenamic acid inhibits the proliferation and migration of human prostate cancer PC-3 cells via an AKR1C3 mechanism.
    Sekine Y; Nakayama H; Miyazawa Y; Kato H; Furuya Y; Arai S; Koike H; Matsui H; Shibata Y; Ito K; Suzuki K
    Oncol Lett; 2018 Mar; 15(3):3167-3172. PubMed ID: 29435052
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combination therapy with novel androgen receptor antagonists and statin for castration-resistant prostate cancer.
    Nakayama H; Sekine Y; Oka D; Miyazawa Y; Arai S; Koike H; Matsui H; Shibata Y; Suzuki K
    Prostate; 2022 Feb; 82(3):314-322. PubMed ID: 34843630
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Simvastatin Up-Regulates Annexin A10 That Can Inhibit the Proliferation, Migration, and Invasion in Androgen-Independent Human Prostate Cancer Cells.
    Miyazawa Y; Sekine Y; Kato H; Furuya Y; Koike H; Suzuki K
    Prostate; 2017 Mar; 77(4):337-349. PubMed ID: 27862098
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Low-density lipoprotein receptors play an important role in the inhibition of prostate cancer cell proliferation by statins.
    Furuya Y; Sekine Y; Kato H; Miyazawa Y; Koike H; Suzuki K
    Prostate Int; 2016 Jun; 4(2):56-60. PubMed ID: 27358845
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interleukin-6 regulates androgen synthesis in prostate cancer cells.
    Chun JY; Nadiminty N; Dutt S; Lou W; Yang JC; Kung HJ; Evans CP; Gao AC
    Clin Cancer Res; 2009 Aug; 15(15):4815-22. PubMed ID: 19638459
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Simvastatin Enhances the Radiosensitivity of Androgen-independent Prostate Cancer Cells
    Oka D; Sekine Y; Tsuji Y; Nakayama H; Miyazawa Y; Arai S; Koike H; Suzuki K
    Anticancer Res; 2024 Jan; 44(1):93-98. PubMed ID: 38159995
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Berberine inhibits androgen synthesis by interaction with aldo-keto reductase 1C3 in 22Rv1 prostate cancer cells.
    Tian Y; Zhao L; Wang Y; Zhang H; Xu D; Zhao X; Li Y; Li J
    Asian J Androl; 2016; 18(4):607-12. PubMed ID: 26698234
    [TBL] [Abstract][Full Text] [Related]  

  • 8. AKR1C3, a crucial androgenic enzyme in prostate cancer, promotes epithelial-mesenchymal transition and metastasis through activating ERK signaling.
    Wang B; Gu Y; Hui K; Huang J; Xu S; Wu S; Li L; Fan J; Wang X; Hsieh JT; He D; Wu K
    Urol Oncol; 2018 Oct; 36(10):472.e11-472.e20. PubMed ID: 30139661
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of simvastatin on castration-resistant prostate cancer cells.
    Kim JH; Cox ME; Wasan KM
    Lipids Health Dis; 2014 Mar; 13():56. PubMed ID: 24666612
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anticancer efficacy of simvastatin on prostate cancer cells and tumor xenografts is associated with inhibition of Akt and reduced prostate-specific antigen expression.
    Kochuparambil ST; Al-Husein B; Goc A; Soliman S; Somanath PR
    J Pharmacol Exp Ther; 2011 Feb; 336(2):496-505. PubMed ID: 21059805
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A 3-(4-nitronaphthen-1-yl) amino-benzoate analog as a bifunctional AKR1C3 inhibitor and AR antagonist: Head to head comparison with other advanced AKR1C3 targeted therapeutics.
    Wangtrakuldee P; Adeniji AO; Zang T; Duan L; Khatri B; Twenter BM; Estrada MA; Higgins TF; Winkler JD; Penning TM
    J Steroid Biochem Mol Biol; 2019 Sep; 192():105283. PubMed ID: 30641225
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Simvastatin Induces Autophagy and Inhibits Proliferation in Prostate Cancer Cells.
    Miyazawa Y; Sekine Y; Oka D; Nakazawa S; Tsuji Y; Nakayama H; Suzuki K
    Anticancer Res; 2023 Dec; 43(12):5377-5386. PubMed ID: 38030198
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Steroidogenic enzyme AKR1C3 is a novel androgen receptor-selective coactivator that promotes prostate cancer growth.
    Yepuru M; Wu Z; Kulkarni A; Yin F; Barrett CM; Kim J; Steiner MS; Miller DD; Dalton JT; Narayanan R
    Clin Cancer Res; 2013 Oct; 19(20):5613-25. PubMed ID: 23995860
    [TBL] [Abstract][Full Text] [Related]  

  • 14. AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells.
    Wang S; Yang Q; Fung KM; Lin HK
    Mol Cell Endocrinol; 2008 Jul; 289(1-2):60-6. PubMed ID: 18508192
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Simvastatin inhibits the proliferation of human prostate cancer PC-3 cells via down-regulation of the insulin-like growth factor 1 receptor.
    Sekine Y; Furuya Y; Nishii M; Koike H; Matsui H; Suzuki K
    Biochem Biophys Res Commun; 2008 Jul; 372(2):356-61. PubMed ID: 18489904
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transition from androgenic to neurosteroidal action of 5α-androstane-3α, 17β-diol through the type A γ-aminobutyric acid receptor in prostate cancer progression.
    Xia D; Lai DV; Wu W; Webb ZD; Yang Q; Zhao L; Yu Z; Thorpe JE; Disch BC; Ihnat MA; Jayaraman M; Dhanasekaran DN; Stratton KL; Cookson MS; Fung KM; Lin HK
    J Steroid Biochem Mol Biol; 2018 Apr; 178():89-98. PubMed ID: 29155210
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The DHEA-sulfate depot following P450c17 inhibition supports the case for AKR1C3 inhibition in high risk localized and advanced castration resistant prostate cancer.
    Tamae D; Mostaghel E; Montgomery B; Nelson PS; Balk SP; Kantoff PW; Taplin ME; Penning TM
    Chem Biol Interact; 2015 Jun; 234():332-8. PubMed ID: 25514466
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Establishing a Proteomics-Based Signature of AKR1C3-Related Genes for Predicting the Prognosis of Prostate Cancer.
    Cui X; Li C; Ding J; Yao Z; Zhao T; Guo J; Wang Y; Li J
    Int J Mol Sci; 2023 Feb; 24(5):. PubMed ID: 36901944
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Statin derivatives as therapeutic agents for castration-resistant prostate cancer.
    Ingersoll MA; Miller DR; Martinez O; Wakefield CB; Hsieh KC; Simha MV; Kao CL; Chen HT; Batra SK; Lin MF
    Cancer Lett; 2016 Dec; 383(1):94-105. PubMed ID: 27687622
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Overexpression of AKR1C3 significantly enhances human prostate cancer cells resistance to radiation.
    Sun SQ; Gu X; Gao XS; Li Y; Yu H; Xiong W; Yu H; Wang W; Li Y; Teng Y; Zhou D
    Oncotarget; 2016 Jul; 7(30):48050-48058. PubMed ID: 27385003
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.