130 related articles for article (PubMed ID: 29436427)
1. Pyruvate Dehydrogenase PDH-E1β Controls Tumor Progression by Altering the Metabolic Status of Cancer Cells.
Yonashiro R; Eguchi K; Wake M; Takeda N; Nakayama K
Cancer Res; 2018 Apr; 78(7):1592-1603. PubMed ID: 29436427
[TBL] [Abstract][Full Text] [Related]
2. Prolyl-hydroxylase PHD3 interacts with pyruvate dehydrogenase (PDH)-E1β and regulates the cellular PDH activity.
Kikuchi D; Minamishima YA; Nakayama K
Biochem Biophys Res Commun; 2014 Aug; 451(2):288-94. PubMed ID: 25088999
[TBL] [Abstract][Full Text] [Related]
3. Prolonged hypoxia decreases nuclear pyruvate dehydrogenase complex and regulates the gene expression.
Eguchi K; Nakayama K
Biochem Biophys Res Commun; 2019 Nov; 520(1):128-135. PubMed ID: 31582221
[TBL] [Abstract][Full Text] [Related]
4. Src drives the Warburg effect and therapy resistance by inactivating pyruvate dehydrogenase through tyrosine-289 phosphorylation.
Jin Y; Cai Q; Shenoy AK; Lim S; Zhang Y; Charles S; Tarrash M; Fu X; Kamarajugadda S; Trevino JG; Tan M; Lu J
Oncotarget; 2016 May; 7(18):25113-24. PubMed ID: 26848621
[TBL] [Abstract][Full Text] [Related]
5. Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect.
Fan J; Kang HB; Shan C; Elf S; Lin R; Xie J; Gu TL; Aguiar M; Lonning S; Chung TW; Arellano M; Khoury HJ; Shin DM; Khuri FR; Boggon TJ; Kang S; Chen J
J Biol Chem; 2014 Sep; 289(38):26533-26541. PubMed ID: 25104357
[TBL] [Abstract][Full Text] [Related]
6. Pyruvate dehydrogenase complex deficiency caused by ubiquitination and proteasome-mediated degradation of the E1 subunit.
Han Z; Zhong L; Srivastava A; Stacpoole PW
J Biol Chem; 2008 Jan; 283(1):237-243. PubMed ID: 17923481
[TBL] [Abstract][Full Text] [Related]
7. Pyruvate dehydrogenase and pyruvate dehydrogenase kinase expression in non small cell lung cancer and tumor-associated stroma.
Koukourakis MI; Giatromanolaki A; Sivridis E; Gatter KC; Harris AL;
Neoplasia; 2005 Jan; 7(1):1-6. PubMed ID: 15736311
[TBL] [Abstract][Full Text] [Related]
8. Differential expression of pyruvate dehydrogenase E1A and its inactive phosphorylated form among breast cancer subtypes.
Zaher DM; Talaat IM; Hussein A; Hachim MY; Omar HA
Life Sci; 2021 Nov; 284():119885. PubMed ID: 34384830
[TBL] [Abstract][Full Text] [Related]
9. Reprogramming of tumor metabolism by targeting mitochondria improves tumor response to irradiation.
Bol V; Bol A; Bouzin C; Labar D; Lee JA; Janssens G; Porporato PE; Sonveaux P; Feron O; Grégoire V
Acta Oncol; 2015 Feb; 54(2):266-74. PubMed ID: 25007226
[TBL] [Abstract][Full Text] [Related]
10. Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis.
Li X; Jiang Y; Meisenhelder J; Yang W; Hawke DH; Zheng Y; Xia Y; Aldape K; He J; Hunter T; Wang L; Lu Z
Mol Cell; 2016 Mar; 61(5):705-719. PubMed ID: 26942675
[TBL] [Abstract][Full Text] [Related]
11. Nutrient deprivation induces the Warburg effect through ROS/AMPK-dependent activation of pyruvate dehydrogenase kinase.
Wu CA; Chao Y; Shiah SG; Lin WW
Biochim Biophys Acta; 2013 May; 1833(5):1147-56. PubMed ID: 23376776
[TBL] [Abstract][Full Text] [Related]
12. Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect.
Zhang W; Zhang SL; Hu X; Tam KY
Eur J Pharm Sci; 2017 Dec; 110():93-100. PubMed ID: 28450154
[TBL] [Abstract][Full Text] [Related]
13. Ras-mediated modulation of pyruvate dehydrogenase activity regulates mitochondrial reserve capacity and contributes to glioblastoma tumorigenesis.
Prabhu A; Sarcar B; Miller CR; Kim SH; Nakano I; Forsyth P; Chinnaiyan P
Neuro Oncol; 2015 Sep; 17(9):1220-30. PubMed ID: 25712957
[TBL] [Abstract][Full Text] [Related]
14. ROS production induced by BRAF inhibitor treatment rewires metabolic processes affecting cell growth of melanoma cells.
Cesi G; Walbrecq G; Zimmer A; Kreis S; Haan C
Mol Cancer; 2017 Jun; 16(1):102. PubMed ID: 28595656
[TBL] [Abstract][Full Text] [Related]
15. Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells.
Feron O
Radiother Oncol; 2009 Sep; 92(3):329-33. PubMed ID: 19604589
[TBL] [Abstract][Full Text] [Related]
16. Lactic acidosis caused by repressed lactate dehydrogenase subunit B expression down-regulates mitochondrial oxidative phosphorylation via the pyruvate dehydrogenase (PDH)-PDH kinase axis.
Hong SM; Lee YK; Park I; Kwon SM; Min S; Yoon G
J Biol Chem; 2019 May; 294(19):7810-7820. PubMed ID: 30923124
[TBL] [Abstract][Full Text] [Related]
17. Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex.
Fan J; Shan C; Kang HB; Elf S; Xie J; Tucker M; Gu TL; Aguiar M; Lonning S; Chen H; Mohammadi M; Britton LM; Garcia BA; Alečković M; Kang Y; Kaluz S; Devi N; Van Meir EG; Hitosugi T; Seo JH; Lonial S; Gaddh M; Arellano M; Khoury HJ; Khuri FR; Boggon TJ; Kang S; Chen J
Mol Cell; 2014 Feb; 53(4):534-48. PubMed ID: 24486017
[TBL] [Abstract][Full Text] [Related]
18. Tyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth.
Shan C; Kang HB; Elf S; Xie J; Gu TL; Aguiar M; Lonning S; Hitosugi T; Chung TW; Arellano M; Khoury HJ; Shin DM; Khuri FR; Boggon TJ; Fan J
J Biol Chem; 2014 Aug; 289(31):21413-22. PubMed ID: 24962578
[TBL] [Abstract][Full Text] [Related]
19. Mitochondrial dysfunction induces radioresistance in colorectal cancer by activating [Ca
Shi Y; Wang Y; Jiang H; Sun X; Xu H; Wei X; Wei Y; Xiao G; Song Z; Zhou F
Cell Death Dis; 2021 Sep; 12(9):837. PubMed ID: 34489398
[TBL] [Abstract][Full Text] [Related]
20. miR‑21‑5p targets PDHA1 to regulate glycolysis and cancer progression in gastric cancer.
Liu Z; Yu M; Fei B; Fang X; Ma T; Wang D
Oncol Rep; 2018 Nov; 40(5):2955-2963. PubMed ID: 30226598
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
