These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 29436980)

  • 1. Virtual screening of natural inhibitors targeting ornithine decarboxylase with pharmacophore scaffolding of DFMO and validation by molecular dynamics simulation studies.
    Sivashanmugam M; K N S; V U
    J Biomol Struct Dyn; 2019 Feb; 37(3):766-780. PubMed ID: 29436980
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure based design of inhibitory peptides targeting ornithine decarboxylase dimeric interface and
    Muthukumaran S; Sulochana KN; Umashankar V
    J Biomol Struct Dyn; 2021 Sep; 39(14):5261-5275. PubMed ID: 32597331
    [TBL] [Abstract][Full Text] [Related]  

  • 3. X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine.
    Grishin NV; Osterman AL; Brooks HB; Phillips MA; Goldsmith EJ
    Biochemistry; 1999 Nov; 38(46):15174-84. PubMed ID: 10563800
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine.
    Qu N; Ignatenko NA; Yamauchi P; Stringer DE; Levenson C; Shannon P; Perrin S; Gerner EW
    Biochem J; 2003 Oct; 375(Pt 2):465-70. PubMed ID: 12859253
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular Modeling and Virtual Screening Approach to Discover Potential Antileishmanial Inhibitors Against Ornithine Decarboxylase.
    Pandey RK; Prajapati P; Goyal S; Grover A; Prajapati VK
    Comb Chem High Throughput Screen; 2016; 19(10):813-823. PubMed ID: 27604958
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Drug repositioning to discover novel ornithine decarboxylase inhibitors against visceral leishmaniasis.
    Sheikh SY; Ansari WA; Hassan F; Faruqui T; Khan MF; Akhter Y; Khan AR; Siddiqui MA; Al-Khedhairy AA; Nasibullah M
    J Mol Recognit; 2023 Jul; 36(7):e3021. PubMed ID: 37092713
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural insight into DFMO resistant ornithine decarboxylase from Entamoeba histolytica: an inkling to adaptive evolution.
    Preeti ; Tapas S; Kumar P; Madhubala R; Tomar S
    PLoS One; 2013; 8(1):e53397. PubMed ID: 23326423
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting ornithine decarboxylase reverses the LIN28/Let-7 axis and inhibits glycolytic metabolism in neuroblastoma.
    Lozier AM; Rich ME; Grawe AP; Peck AS; Zhao P; Chang AT; Bond JP; Sholler GS
    Oncotarget; 2015 Jan; 6(1):196-206. PubMed ID: 25415050
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Purification and Characterization of Ornithine Decarboxylase from
    El-Sayed ASA; George NM; Yassin MA; Alaidaroos BA; Bolbol AA; Mohamed MS; Rady AM; Aziz SW; Zayed RA; Sitohy MZ
    Molecules; 2019 Jul; 24(15):. PubMed ID: 31362455
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Eflornithine (DFMO) prevents progression of pancreatic cancer by modulating ornithine decarboxylase signaling.
    Mohammed A; Janakiram NB; Madka V; Ritchie RL; Brewer M; Biddick L; Patlolla JM; Sadeghi M; Lightfoot S; Steele VE; Rao CV
    Cancer Prev Res (Phila); 2014 Dec; 7(12):1198-209. PubMed ID: 25248858
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy.
    Geck RC; Foley JR; Murray Stewart T; Asara JM; Casero RA; Toker A
    J Biol Chem; 2020 May; 295(19):6263-6277. PubMed ID: 32139506
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport.
    Samal K; Zhao P; Kendzicky A; Yco LP; McClung H; Gerner E; Burns M; Bachmann AS; Sholler G
    Int J Cancer; 2013 Sep; 133(6):1323-33. PubMed ID: 23457004
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity.
    Kim DJ; Roh E; Lee MH; Oi N; Lim DY; Kim MO; Cho YY; Pugliese A; Shim JH; Chen H; Cho EJ; Kim JE; Kang SC; Paul S; Kang HE; Jung JW; Lee SY; Kim SH; Reddy K; Yeom YI; Bode AM; Dong Z
    Cancer Res; 2016 Mar; 76(5):1146-1157. PubMed ID: 26676750
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Phase I Trial of DFMO Targeting Polyamine Addiction in Patients with Relapsed/Refractory Neuroblastoma.
    Saulnier Sholler GL; Gerner EW; Bergendahl G; MacArthur RB; VanderWerff A; Ashikaga T; Bond JP; Ferguson W; Roberts W; Wada RK; Eslin D; Kraveka JM; Kaplan J; Mitchell D; Parikh NS; Neville K; Sender L; Higgins T; Kawakita M; Hiramatsu K; Moriya SS; Bachmann AS
    PLoS One; 2015; 10(5):e0127246. PubMed ID: 26018967
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Alpha-difluoromethylornithine resistance in Leishmania donovani is associated with increased ornithine decarboxylase activity.
    Coons T; Hanson S; Bitonti AJ; McCann PP; Ullman B
    Mol Biochem Parasitol; 1990 Feb; 39(1):77-89. PubMed ID: 2154691
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ornithine decarboxylase over-expression stimulates mitogen-activated protein kinase and anchorage-independent growth of human breast epithelial cells.
    Manni A; Wechter R; Gilmour S; Verderame MF; Mauger D; Demers LM
    Int J Cancer; 1997 Jan; 70(2):175-82. PubMed ID: 9009157
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biochemical changes associated with alpha-difluoromethylornithine uptake and resistance in Trypanosoma brucei.
    Bellofatto V; Fairlamb AH; Henderson GB; Cross GA
    Mol Biochem Parasitol; 1987 Oct; 25(3):227-38. PubMed ID: 3122042
    [TBL] [Abstract][Full Text] [Related]  

  • 18. On the translational control of ornithine decarboxylase expression by polyamines.
    Stjernborg L; Heby O; Holm I; Persson L
    Biochim Biophys Acta; 1991 Oct; 1090(2):188-94. PubMed ID: 1932110
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The rational discovery of multipurpose inhibitors of the ornithine decarboxylase.
    Chai X; Zhan J; Pan J; He M; Li B; Wang J; Ma H; Wang Y; Liu S
    FASEB J; 2020 Sep; 34(9):10907-12921. PubMed ID: 32767470
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Trypanosoma cruzi as a model system to study the expression of exogenous genes coding for polyamine biosynthetic enzymes. Induction of DFMO resistance in transgenic parasites.
    Carrillo C; González NS; Algranati ID
    Biochim Biophys Acta; 2007 Dec; 1770(12):1605-11. PubMed ID: 17920200
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.