208 related articles for article (PubMed ID: 29445088)
1. Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations.
Yaglom JA; Wang Y; Li A; Li Z; Monti S; Alexandrov I; Lu X; Sherman MY
Sci Rep; 2018 Feb; 8(1):3010. PubMed ID: 29445088
[TBL] [Abstract][Full Text] [Related]
2. Pharmacological inhibition of BAG3-HSP70 with the proposed cancer therapeutic JG-98 is toxic for cardiomyocytes.
Martin TG; Delligatti CE; Muntu NA; Stachowski-Doll MJ; Kirk JA
J Cell Biochem; 2022 Jan; 123(1):128-141. PubMed ID: 34487557
[TBL] [Abstract][Full Text] [Related]
3. A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.
Massey AJ; Williamson DS; Browne H; Murray JB; Dokurno P; Shaw T; Macias AT; Daniels Z; Geoffroy S; Dopson M; Lavan P; Matassova N; Francis GL; Graham CJ; Parsons R; Wang Y; Padfield A; Comer M; Drysdale MJ; Wood M
Cancer Chemother Pharmacol; 2010 Aug; 66(3):535-45. PubMed ID: 20012863
[TBL] [Abstract][Full Text] [Related]
4. Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer.
Li X; Colvin T; Rauch JN; Acosta-Alvear D; Kampmann M; Dunyak B; Hann B; Aftab BT; Murnane M; Cho M; Walter P; Weissman JS; Sherman MY; Gestwicki JE
Mol Cancer Ther; 2015 Mar; 14(3):642-8. PubMed ID: 25564440
[TBL] [Abstract][Full Text] [Related]
5. Sensitization of multidrug-resistant human cancer cells to Hsp90 inhibitors by down-regulation of SIRT1.
Kim HB; Lee SH; Um JH; Oh WK; Kim DW; Kang CD; Kim SH
Oncotarget; 2015 Nov; 6(34):36202-18. PubMed ID: 26416354
[TBL] [Abstract][Full Text] [Related]
6. The Hsp70 inhibiting peptide aptamer A17 potentiates radiosensitization of tumor cells by Hsp90 inhibition.
Schilling D; Garrido C; Combs SE; Multhoff G
Cancer Lett; 2017 Apr; 390():146-152. PubMed ID: 28108313
[TBL] [Abstract][Full Text] [Related]
7. CPUY201112, a novel synthetic small-molecule compound and inhibitor of heat shock protein Hsp90, induces p53-mediated apoptosis in MCF-7 cells.
Xu XL; Bao QC; Jia JM; Liu F; Guo XK; Zhang MY; Wei JL; Lu MC; Xu LL; Zhang XJ; You QD; Sun HP
Sci Rep; 2016 Jan; 6():19004. PubMed ID: 26743233
[TBL] [Abstract][Full Text] [Related]
8. The HSP90 inhibitor NVP-AUY922-AG inhibits the PI3K and IKK signalling pathways and synergizes with cytarabine in acute myeloid leukaemia cells.
Walsby EJ; Lazenby M; Pepper CJ; Knapper S; Burnett AK
Br J Haematol; 2013 Apr; 161(1):57-67. PubMed ID: 23356405
[TBL] [Abstract][Full Text] [Related]
9. Comparison of the activity of three different HSP70 inhibitors on apoptosis, cell cycle arrest, autophagy inhibition, and HSP90 inhibition.
Budina-Kolomets A; Balaburski GM; Bondar A; Beeharry N; Yen T; Murphy ME
Cancer Biol Ther; 2014 Feb; 15(2):194-9. PubMed ID: 24100579
[TBL] [Abstract][Full Text] [Related]
10. Development of Novel Rhodacyanine-Based Heat Shock Protein 70 Inhibitors.
Chang CS; Kumar V; Lee DY; Chen Y; Wu YC; Gao JY; Chu PC
Curr Med Chem; 2021; 28(26):5431-5446. PubMed ID: 33538660
[TBL] [Abstract][Full Text] [Related]
11. Heat shock proteins and cancer: The FoxM1 connection.
Alimardan Z; Abbasi M; Hasanzadeh F; Aghaei M; Khodarahmi G; Kashfi K
Biochem Pharmacol; 2023 May; 211():115505. PubMed ID: 36931349
[TBL] [Abstract][Full Text] [Related]
12. Combined inhibition of heat shock proteins 90 and 70 leads to simultaneous degradation of the oncogenic signaling proteins involved in muscle invasive bladder cancer.
Cavanaugh A; Juengst B; Sheridan K; Danella JF; Williams H
Oncotarget; 2015 Nov; 6(37):39821-38. PubMed ID: 26556859
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of HSP70: a challenging anti-cancer strategy.
Goloudina AR; Demidov ON; Garrido C
Cancer Lett; 2012 Dec; 325(2):117-24. PubMed ID: 22750096
[TBL] [Abstract][Full Text] [Related]
14. Virtual screening based identification of miltefosine and octenidine as inhibitors of heat shock protein 90.
Li L; Yang M; Li C; Liu Y
Naunyn Schmiedebergs Arch Pharmacol; 2021 Nov; 394(11):2223-2232. PubMed ID: 34406420
[TBL] [Abstract][Full Text] [Related]
15. Chaperone substrate provides missing link for cancer drug discovery.
Byrd KM; Blagg BSJ
J Biol Chem; 2018 Feb; 293(7):2381-2382. PubMed ID: 29453286
[TBL] [Abstract][Full Text] [Related]
16. HSP90 and HSP70: Implication in Inflammation Processes and Therapeutic Approaches for Myeloproliferative Neoplasms.
Sevin M; Girodon F; Garrido C; de Thonel A
Mediators Inflamm; 2015; 2015():970242. PubMed ID: 26549943
[TBL] [Abstract][Full Text] [Related]
17. Synergism between arsenic trioxide and heat shock protein 90 inhibitors on signal transducer and activator of transcription protein 3 activity--pharmacodynamic drug-drug interaction modeling.
Wetzler M; Earp JC; Brady MT; Keng MK; Jusko WJ
Clin Cancer Res; 2007 Apr; 13(7):2261-70. PubMed ID: 17404111
[TBL] [Abstract][Full Text] [Related]
18. Induction of Hsp70 in tumor cells treated with inhibitors of the Hsp90 activity: A predictive marker and promising target for radiosensitization.
Kudryavtsev VA; Khokhlova AV; Mosina VA; Selivanova EI; Kabakov AE
PLoS One; 2017; 12(3):e0173640. PubMed ID: 28291803
[TBL] [Abstract][Full Text] [Related]
19. High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer.
Jansson KH; Tucker JB; Stahl LE; Simmons JK; Fuller C; Beshiri ML; Agarwal S; Fang L; Hynes PG; Alilin AN; Lake R; Abbey YC; Cawley J; Tice CM; Yin J; McKnight C; Klummp-Thomas C; Zhang X; Guha R; Hoover S; Simpson RM; Nguyen HM; Corey E; Thomas CJ; Proia DA; Kelly K
Sci Rep; 2018 Nov; 8(1):17239. PubMed ID: 30467317
[TBL] [Abstract][Full Text] [Related]
20. mTOR inhibition potentiates HSP90 inhibitor activity via cessation of HSP synthesis.
Acquaviva J; He S; Sang J; Smith DL; Sequeira M; Zhang C; Bates RC; Proia DA
Mol Cancer Res; 2014 May; 12(5):703-13. PubMed ID: 24554781
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
