BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 29449434)

  • 1. MSH6 haploinsufficiency at relapse contributes to the development of thiopurine resistance in pediatric B-lymphoblastic leukemia.
    Evensen NA; Madhusoodhan PP; Meyer J; Saliba J; Chowdhury A; Araten DJ; Nersting J; Bhatla T; Vincent TL; Teachey D; Hunger SP; Yang J; Schmiegelow K; Carroll WL
    Haematologica; 2018 May; 103(5):830-839. PubMed ID: 29449434
    [TBL] [Abstract][Full Text] [Related]  

  • 2.
    Xu H; Zhao X; Bhojwani D; E S; Goodings C; Zhang H; Seibel NL; Yang W; Li C; Carroll WL; Evans WE; Yang JJ
    Clin Cancer Res; 2020 Jan; 26(1):256-264. PubMed ID: 31573954
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial.
    Nielsen SN; Grell K; Nersting J; Abrahamsson J; Lund B; Kanerva J; Jónsson ÓG; Vaitkeviciene G; Pruunsild K; Hjalgrim LL; Schmiegelow K
    Lancet Oncol; 2017 Apr; 18(4):515-524. PubMed ID: 28258828
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The NSD2 p.E1099K Mutation Is Enriched at Relapse and Confers Drug Resistance in a Cell Context-Dependent Manner in Pediatric Acute Lymphoblastic Leukemia.
    Pierro J; Saliba J; Narang S; Sethia G; Saint Fleur-Lominy S; Chowdhury A; Qualls A; Fay H; Kilberg HL; Moriyama T; Fuller TJ; Teachey DT; Schmiegelow K; Yang JJ; Loh ML; Brown PA; Zhang J; Ma X; Tsirigos A; Evensen NA; Carroll WL
    Mol Cancer Res; 2020 Aug; 18(8):1153-1165. PubMed ID: 32332049
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of DNA mismatch repair proteins in acute lymphoblastic leukaemia and normal bone marrow.
    Matheson EC; Hall AG
    Adv Exp Med Biol; 1999; 457():579-83. PubMed ID: 10500837
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment.
    Coulthard SA; Matheson EC; Hall AG; Hogarth LA
    Nucleosides Nucleotides Nucleic Acids; 2004 Oct; 23(8-9):1385-91. PubMed ID: 15571264
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Drug-resistance Profile in Multiple-relapsed Childhood Acute Lymphoblastic Leukemia.
    Pogorzala M; Kubicka M; Rafinska B; Wysocki M; Styczynski J
    Anticancer Res; 2015 Oct; 35(10):5667-70. PubMed ID: 26408741
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance.
    Nowak D; Liem NL; Mossner M; Klaumünzer M; Papa RA; Nowak V; Jann JC; Akagi T; Kawamata N; Okamoto R; Thoennissen NH; Kato M; Sanada M; Hofmann WK; Ogawa S; Marshall GM; Lock RB; Koeffler HP
    Exp Hematol; 2015 Jan; 43(1):32-43.e1-35. PubMed ID: 25450514
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia.
    Li B; Brady SW; Ma X; Shen S; Zhang Y; Li Y; Szlachta K; Dong L; Liu Y; Yang F; Wang N; Flasch DA; Myers MA; Mulder HL; Ding L; Liu Y; Tian L; Hagiwara K; Xu K; Zhou X; Sioson E; Wang T; Yang L; Zhao J; Zhang H; Shao Y; Sun H; Sun L; Cai J; Sun HY; Lin TN; Du L; Li H; Rusch M; Edmonson MN; Easton J; Zhu X; Zhang J; Cheng C; Raphael BJ; Tang J; Downing JR; Alexandrov LB; Zhou BS; Pui CH; Yang JJ; Zhang J
    Blood; 2020 Jan; 135(1):41-55. PubMed ID: 31697823
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Increments in DNA-thioguanine level during thiopurine-enhanced maintenance therapy of acute lymphoblastic leukemia.
    Larsen RH; Utke Rank C; Grell K; Nørgaard Møller L; Malthe Overgaard U; Kampmann P; Nersting J; Degn M; Nygaard Nielsen S; Holst H; Klug Albertsen B; Skov Wehner P; Thude Callesen M; Kanerva J; Leth Frandsen T; Als-Nielsen B; Lyngsie Hjalgrim L; Schmiegelow K
    Haematologica; 2021 Nov; 106(11):2824-2833. PubMed ID: 34047177
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thiopurine Resistance in Childhood ALL Is Mediated by PRPS1 Mutations.
    Cancer Discov; 2015 Jul; 5(7):693. PubMed ID: 25998402
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Resistance to 6-thioguanine in mismatch repair-deficient human cancer cell lines correlates with an increase in induced mutations at the HPRT locus.
    Glaab WE; Risinger JI; Umar A; Barrett JC; Kunkel TA; Tindall KR
    Carcinogenesis; 1998 Nov; 19(11):1931-7. PubMed ID: 9855005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential role of thiopurine methyltransferase in the cytotoxic effects of 6-mercaptopurine and 6-thioguanine on human leukemia cells.
    Karim H; Ghalali A; Lafolie P; Vitols S; Fotoohi AK
    Biochem Biophys Res Commun; 2013 Jul; 437(2):280-6. PubMed ID: 23811272
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia.
    Tulstrup M; Grosjean M; Nielsen SN; Grell K; Wolthers BO; Wegener PS; Jonsson OG; Lund B; Harila-Saari A; Abrahamsson J; Vaitkeviciene G; Pruunsild K; Toft N; Holm M; Hulegårdh E; Liestøl S; Griskevicius L; Punab M; Wang J; Carroll WL; Zhang Z; Dalgaard MD; Gupta R; Nersting J; Schmiegelow K
    Leukemia; 2018 Dec; 32(12):2527-2535. PubMed ID: 30201983
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy.
    Sengupta TK; Leclerc GM; Hsieh-Kinser TT; Leclerc GJ; Singh I; Barredo JC
    Mol Cancer; 2007 Jul; 6():46. PubMed ID: 17623090
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 6-Thioguanine-induced growth arrest in 6-mercaptopurine-resistant human leukemia cells.
    Morgan CJ; Chawdry RN; Smith AR; Siravo-Sagraves G; Trewyn RW
    Cancer Res; 1994 Oct; 54(20):5387-93. PubMed ID: 7923170
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel protein complex distinct from mismatch repair binds thioguanylated DNA.
    Krynetski EY; Krynetskaia NF; Gallo AE; Murti KG; Evans WE
    Mol Pharmacol; 2001 Feb; 59(2):367-74. PubMed ID: 11160874
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacokinetics of 6-Thioguanine and 6-Mercaptopurine Combination Maintenance Therapy of Childhood ALL: Hypothesis and Case Report.
    Nielsen SN; Frandsen TL; Nersting J; Hjalgrim LL; Schmiegelow K
    J Pediatr Hematol Oncol; 2015 Apr; 37(3):e206-9. PubMed ID: 25171455
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis.
    Kuraguchi M; Yang K; Wong E; Avdievich E; Fan K; Kolodner RD; Lipkin M; Brown AM; Kucherlapati R; Edelmann W
    Cancer Res; 2001 Nov; 61(21):7934-42. PubMed ID: 11691815
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA-thioguanine concentration and relapse risk in children and young adults with acute lymphoblastic leukemia: an IPD meta-analysis.
    Toksvang LN; Grell K; Nersting J; Degn M; Nielsen SN; Abrahamsson J; Lund B; Kanerva J; Jónsson ÓG; Lepik K; Vaitkevičienė G; Griškevičius L; Quist-Paulsen P; Vora A; Moorman AV; Murdy D; Zimmermann M; Möricke A; Bostrom B; Joshi J; Hjalgrim LL; Dalhoff KP; Als-Nielsen B; Schmiegelow K
    Leukemia; 2022 Jan; 36(1):33-41. PubMed ID: 34175901
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.