BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 29449607)

  • 1. 6-Thioguanine is a noncompetitive and slow binding inhibitor of human deubiquitinating protease USP2.
    Chuang SJ; Cheng SC; Tang HC; Sun CY; Chou CY
    Sci Rep; 2018 Feb; 8(1):3102. PubMed ID: 29449607
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis of ubiquitin recognition by the deubiquitinating protease USP2.
    Renatus M; Parrado SG; D'Arcy A; Eidhoff U; Gerhartz B; Hassiepen U; Pierrat B; Riedl R; Vinzenz D; Worpenberg S; Kroemer M
    Structure; 2006 Aug; 14(8):1293-302. PubMed ID: 16905103
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models.
    Davis MI; Pragani R; Fox JT; Shen M; Parmar K; Gaudiano EF; Liu L; Tanega C; McGee L; Hall MD; McKnight C; Shinn P; Nelson H; Chattopadhyay D; D'Andrea AD; Auld DS; DeLucas LJ; Li Z; Boxer MB; Simeonov A
    J Biol Chem; 2016 Nov; 291(47):24628-24640. PubMed ID: 27681596
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Yeast Two-Hybrid Analysis for Ubiquitin Variant Inhibitors of Human Deubiquitinases.
    Pascoe N; Seetharaman A; Teyra J; Manczyk N; Satori MA; Tjandra D; Makhnevych T; Schwerdtfeger C; Brasher BB; Moffat J; Costanzo M; Boone C; Sicheri F; Sidhu SS
    J Mol Biol; 2019 Mar; 431(6):1160-1171. PubMed ID: 30763569
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deubiquitinating enzymes in skeletal muscle atrophy-An essential role for USP19.
    Wing SS
    Int J Biochem Cell Biol; 2016 Oct; 79():462-468. PubMed ID: 27475983
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disulfiram and 6-Thioguanine synergistically inhibit the enzymatic activities of USP2 and USP21.
    Lin HC; Kuan Y; Chu HF; Cheng SC; Pan HC; Chen WY; Sun CY; Lin TH
    Int J Biol Macromol; 2021 Apr; 176():490-497. PubMed ID: 33582217
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ribonucleotide reductase holoenzyme inhibitor COH29 interacts with deubiquitinase ubiquitin-specific protease 2 and downregulates its substrate protein cyclin D1.
    Zhu M; Wang H; Ding Y; Yang Y; Xu Z; Shi L; Zhang N
    FASEB J; 2022 May; 36(5):e22329. PubMed ID: 35476303
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Validation of catalytic site residues of Ubiquitin Specific Protease 2 (USP2) by molecular dynamic simulation and novel kinetics assay for rational drug design.
    Ullah S; Junaid M; Liu Y; Chen S; Zhao Y; Wadood A
    Mol Divers; 2023 Jun; 27(3):1323-1332. PubMed ID: 35932436
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of a highly reliable assay for ubiquitin-specific protease 2 inhibitors.
    Wang Z; Xie W; Zhu M; Zhou H
    Bioorg Med Chem Lett; 2017 Sep; 27(17):4015-4018. PubMed ID: 28778469
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Deubiquitylase USP2 Regulates the LDLR Pathway by Counteracting the E3-Ubiquitin Ligase IDOL.
    Nelson JK; Sorrentino V; Avagliano Trezza R; Heride C; Urbe S; Distel B; Zelcer N
    Circ Res; 2016 Feb; 118(3):410-9. PubMed ID: 26666640
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased acid ceramidase expression depends on upregulation of androgen-dependent deubiquitinases, USP2, in a human prostate cancer cell line, LNCaP.
    Mizutani N; Inoue M; Omori Y; Ito H; Tamiya-Koizumi K; Takagi A; Kojima T; Nakamura M; Iwaki S; Nakatochi M; Suzuki M; Nozawa Y; Murate T
    J Biochem; 2015 Oct; 158(4):309-19. PubMed ID: 25888580
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels.
    Krzystanek K; Rasmussen HB; Grunnet M; Staub O; Olesen SP; Abriel H; Jespersen T
    Heart Rhythm; 2012 Mar; 9(3):440-8. PubMed ID: 22024150
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Deubiquitinating enzymes as cancer biomarkers: new therapeutic opportunities?
    Poondla N; Chandrasekaran AP; Kim KS; Ramakrishna S
    BMB Rep; 2019 Mar; 52(3):181-189. PubMed ID: 30760385
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting the deubiquitinase
    Zhang S; Guo Y; Zhang S; Wang Z; Zhang Y; Zuo S
    Oncol Rep; 2023 Oct; 50(4):. PubMed ID: 37594087
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deubiquitinase USP35 as a novel mitotic regulator via maintenance of Aurora B stability.
    Park J; Song EJ
    BMB Rep; 2018 Jun; 51(6):261-262. PubMed ID: 29764563
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ubiquitin-specific protease 2-45 (Usp2-45) binds to epithelial Na+ channel (ENaC)-ubiquitylating enzyme Nedd4-2.
    Oberfeld B; Ruffieux-Daidié D; Vitagliano JJ; Pos KM; Verrey F; Staub O
    Am J Physiol Renal Physiol; 2011 Jul; 301(1):F189-96. PubMed ID: 21478478
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Control of AIF-mediated cell death by antagonistic functions of CHIP ubiquitin E3 ligase and USP2 deubiquitinating enzyme.
    Oh KH; Yang SW; Park JM; Seol JH; Iemura S; Natsume T; Murata S; Tanaka K; Jeon YJ; Chung CH
    Cell Death Differ; 2011 Aug; 18(8):1326-36. PubMed ID: 21293491
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gene structure, alternate splicing, tissue distribution, cellular localization, and developmental expression pattern of mouse deubiquitinating enzyme isoforms Usp2-45 and Usp2-69.
    Gousseva N; Baker RT
    Gene Expr; 2003; 11(3-4):163-79. PubMed ID: 14686789
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Effects of ubiquitin-specific proteases 2-69 on proliferation of breast cancer cells].
    Liu JY; Zou LP; Wu HJ; Zhao ZH; Zhang ZG
    Zhonghua Bing Li Xue Za Zhi; 2018 Jun; 47(6):455-460. PubMed ID: 29886591
    [No Abstract]   [Full Text] [Related]  

  • 20. Transient kinetic analysis of USP2-catalyzed deubiquitination reveals a conformational rearrangement in the K48-linked diubiquitin substrate.
    Bozza WP; Liang Q; Gong P; Zhuang Z
    Biochemistry; 2012 Dec; 51(50):10075-86. PubMed ID: 23211065
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.